Shawn C. Little
Shawn C. Little
Assistant Professor, Univ. Pennsylvania
Verified email at
Cited by
Cited by
Precise developmental gene expression arises from globally stochastic transcriptional activity
SC Little, M Tikhonov, T Gregor
Cell 154 (4), 789-800, 2013
Bone morphogenetic protein heterodimers assemble heteromeric type I receptor complexes to pattern the dorsoventral axis
SC Little, MC Mullins
Nature cell biology 11 (5), 637-643, 2009
The fibrodysplasia ossificans progressiva R206H ACVR1 mutation activates BMP-independent chondrogenesis and zebrafish embryo ventralization
Q Shen, SC Little, M Xu, J Haupt, C Ast, T Katagiri, S Mundlos, ...
The Journal of clinical investigation 119 (11), 3462-3472, 2009
Analysis of the properties of spores of Bacillus subtilis prepared at different temperatures
E Melly, PC Genest, ME Gilmore, S Little, DL Popham, A Driks, P Setlow
Journal of applied microbiology 92 (6), 1105-1115, 2002
The formation of the Bicoid morphogen gradient requires protein movement from anteriorly localized mRNA
SC Little, G Tkačik, TB Kneeland, EF Wieschaus, T Gregor
PLoS Biol 9 (3), e1000596, 2011
Extracellular modulation of BMP activity in patterning the dorsoventral axis
SC Little, MC Mullins
Birth Defects Research Part C: Embryo Today: Reviews 78 (3), 224-242, 2006
Independent and coordinate trafficking of single Drosophila germ plasm mRNAs
SC Little, KS Sinsimer, JJ Lee, EF Wieschaus, ER Gavis
Nature cell biology 17 (5), 558-568, 2015
The pro-BMP activity of Twisted gastrulation is independent of BMP binding
M Oelgeschläger, B Reversade, J Larraín, S Little, MC Mullins, ...
Development 130 (17), 4047-4056, 2003
Functional analysis of the Bacillus subtilis morphogenetic spore coat protein CotE
S Little, A Driks
Molecular microbiology 42 (4), 1107-1120, 2001
Twisted gastrulation promotes BMP signaling in zebrafish dorsal-ventral axial patterning
SC Little, MC Mullins
Development 131 (23), 5825-5835, 2004
Functional regions of the Bacillus subtilis spore coat morphogenetic protein CotE
T Bauer, S Little, AG Stöver, A Driks
Journal of bacteriology 181 (22), 7043-7051, 1999
Diverse spatial expression patterns emerge from unified kinetics of transcriptional bursting
B Zoller, SC Little, T Gregor
Cell 175 (3), 835-847. e25, 2018
The embryo as a laboratory: quantifying transcription in Drosophila
T Gregor, HG Garcia, SC Little
Trends in Genetics 30 (8), 364-375, 2014
Maternal origins of developmental reproducibility
MD Petkova, SC Little, F Liu, T Gregor
Current Biology 24 (11), 1283-1288, 2014
Oncogenic Notch promotes long-range regulatory interactions within hyperconnected 3D cliques
J Petrovic, Y Zhou, M Fasolino, N Goldman, GW Schwartz, MR Mumbach, ...
Molecular cell 73 (6), 1174-1190. e12, 2019
Only accessible information is useful: insights from gradient-mediated patterning
M Tikhonov, SC Little, T Gregor
Royal Society open science 2 (11), 150486, 2015
Chromatin targeting of nuclear pore proteins induces chromatin decondensation
TM Kuhn, P Pascual-Garcia, A Gozalo, SC Little, M Capelson
Journal of Cell Biology 218 (9), 2945-2961, 2019
Genetic variation in type 1 diabetes reconfigures the 3D chromatin organization of T cells and alters gene expression
M Fasolino, N Goldman, W Wang, B Cattau, Y Zhou, J Petrovic, VM Link, ...
Immunity 52 (2), 257-274. e11, 2020
Spatiotemporal patterning of zygotic genome activation in a model vertebrate embryo
H Chen, LC Einstein, SC Little, MC Good
Developmental cell 49 (6), 852-866. e7, 2019
Shifting patterns: merging molecules, morphogens, motility, and methodology
SC Little, EF Wieschaus
Developmental cell 21 (1), 2-4, 2011
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