Plasma membrane calcium ATPase deficiency causes neuronal pathology in the spinal cord: a potential mechanism for neurodegeneration in multiple sclerosis and spinal cord injury MP Kurnellas, A Nicot, GE Shull, S Elkabes The FASEB journal: official publication of the Federation of American …, 2005 | 111 | 2005 |
Optimized proteomic analysis of a mouse model of cerebellar dysfunction using amine‐specific isobaric tags J Hu, J Qian, O Borisov, S Pan, Y Li, T Liu, L Deng, K Wannemacher, ... Proteomics 6 (15), 4321-4334, 2006 | 91 | 2006 |
Therapeutic effects of systemic administration of chaperone αB-crystallin associated with binding proinflammatory plasma proteins JB Rothbard, MP Kurnellas, S Brownell, CM Adams, L Su, RC Axtell, ... Journal of Biological Chemistry 287 (13), 9708-9721, 2012 | 89 | 2012 |
Identification of differentially expressed proteins in experimental autoimmune encephalomyelitis (EAE) by proteomic analysis of the spinal cord T Liu, KC Donahue, J Hu, MP Kurnellas, JE Grant, H Li, S Elkabes Journal of proteome research 6 (7), 2565-2575, 2007 | 73 | 2007 |
Amyloid fibrils composed of hexameric peptides attenuate neuroinflammation MP Kurnellas, CM Adams, RA Sobel, L Steinman, JB Rothbard Science translational medicine 5 (179), 179ra42-179ra42, 2013 | 71 | 2013 |
Chaperone activity of small heat shock proteins underlies therapeutic efficacy in experimental autoimmune encephalomyelitis MP Kurnellas, SE Brownell, L Su, AV Malkovskiy, J Rajadas, G Dolganov, ... Journal of Biological Chemistry 287 (43), 36423-36434, 2012 | 57 | 2012 |
Molecular alterations in the cerebellum of the plasma membrane calcium ATPase 2 (PMCA2)-null mouse indicate abnormalities in Purkinje neurons MP Kurnellas, AK Lee, H Li, L Deng, DJ Ehrlich, S Elkabes Molecular and Cellular Neuroscience 34 (2), 178-188, 2007 | 56 | 2007 |
Reduced expression of plasma membrane calcium ATPase 2 and collapsin response mediator protein 1 promotes death of spinal cord neurons MP Kurnellas, H Li, MR Jain, SN Giraud, AB Nicot, A Ratnayake, ... Cell Death & Differentiation 17 (9), 1501-1510, 2010 | 54 | 2010 |
Mechanisms of neuronal damage in multiple sclerosis and its animal models: role of calcium pumps and exchangers MP Kurnellas, KC Donahue, S Elkabes Biochemical Society Transactions 35 (5), 923-926, 2007 | 54 | 2007 |
Chaperone activity of α B-crystallin is responsible for its incorrect assignment as an autoantigen in multiple sclerosis JB Rothbard, X Zhao, O Sharpe, MJ Strohman, M Kurnellas, ED Mellins, ... The Journal of Immunology 186 (7), 4263-4268, 2011 | 42 | 2011 |
Temporal pattern of plasma membrane calcium ATPase 2 expression in the spinal cord correlates with the course of clinical symptoms in two rodent models of autoimmune … A Nicot, M Kurnellas, S Elkabes European Journal of Neuroscience 21 (10), 2660-2670, 2005 | 39 | 2005 |
Amyloid fibrils activate B-1a lymphocytes to ameliorate inflammatory brain disease MP Kurnellas, EEB Ghosn, JM Schartner, J Baker, JJ Rothbard, ... Proceedings of the National Academy of Sciences 112 (49), 15016-15023, 2015 | 26 | 2015 |
Calcium responses of chicken trigeminal ganglion neurons to methyl anthranilate and capsaicin ML Kirifides, MP Kurnellas, L Clark, BP Bryant Journal of experimental biology 207 (5), 715-722, 2004 | 22 | 2004 |
Reductions in motor unit number estimates (MUNE) precede motor neuron loss in the plasma membrane calcium ATPase 2 (PMCA2)-heterozygous mice N Souayah, A Sharovetskaya, MP Kurnellas, M Myerson, JS Deitch, ... Experimental neurology 214 (2), 341-346, 2008 | 21 | 2008 |
Mechanisms of action of therapeutic amyloidogenic hexapeptides in amelioration of inflammatory brain disease MP Kurnellas, JM Schartner, CG Fathman, A Jagger, L Steinman, ... Journal of Experimental Medicine 211 (9), 1847-1856, 2014 | 17 | 2014 |
Janus faces of amyloid proteins in neuroinflammation L Steinman, JB Rothbard, MP Kurnellas Journal of clinical immunology 34, 61-63, 2014 | 14 | 2014 |
Role of plasma membrane calcium ATPase isoform 2 in neuronal function in the cerebellum and spinal cord MP Kurnellas, AK Lee, K Szczepanowski, S Elkabes Annals of the New York Academy of Sciences 1099 (1), 287-291, 2007 | 12 | 2007 |
Piet Mondrian’s trees and the evolution in understanding multiple sclerosis, Charcot Prize Lecture 2011 L Steinman, RC Axtell, D Barbieri, R Bhat, SE Brownell, BA De Jong, ... Multiple Sclerosis Journal 19 (1), 5-14, 2013 | 10 | 2013 |
Small heat shock proteins, amyloid fibrils, and nicotine stimulate a common immune suppressive pathway with implications for future therapies JB Rothbard, MP Kurnellas, SS Ousman, S Brownell, JJ Rothbard, ... Cold Spring Harbor Perspectives in Medicine 9 (7), a034223, 2019 | 9 | 2019 |
Self-assembling peptides form immune suppressive amyloid fibrils effective in autoimmune encephalomyelitis MP Kurnellas, JB Rothbard, L Steinman Emerging and Evolving Topics in Multiple Sclerosis Pathogenesis and …, 2015 | 9 | 2015 |