Matthew David Berg
Matthew David Berg
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Pathways to disease from natural variations in human cytoplasmic tRNAs
JT Lant, MD Berg, IU Heinemann, CJ Brandl, P O’Donoghue
Journal of Biological Chemistry 294 (14), 5294-5308, 2019
Genetic selection for mistranslation rescues a defective co-chaperone in yeast
KS Hoffman, MD Berg, BH Shilton, CJ Brandl, P O'Donoghue
Nucleic acids research 45 (6), 3407-3421, 2017
Visualizing tRNA-dependent mistranslation in human cells
JT Lant, MD Berg, DHW Sze, KS Hoffman, IC Akinpelu, MA Turk, ...
RNA biology 15 (4-5), 567-575, 2018
Transfer RNAs: diversity in form and function
MD Berg, CJ Brandl
RNA biology 18 (3), 316-339, 2021
Evolving Mistranslating tRNAs Through a Phenotypically Ambivalent Intermediate in Saccharomyces cerevisiae
MD Berg, KS Hoffman, J Genereaux, S Mian, RS Trussler, DB Haniford, ...
Genetics 206 (4), 1865-1879, 2017
Modulating Mistranslation Potential of tRNASer in Saccharomyces cerevisiae
MD Berg, Y Zhu, J Genereaux, BY Ruiz, RA Rodriguez-Mias, T Allan, ...
Genetics 213 (3), 849-863, 2019
The Pseudokinase Domain of Saccharomyces cerevisiae Tra1 Is Required for Nuclear Localization and Incorporation into the SAGA and NuA4 Complexes
MD Berg, J Genereaux, J Karagiannis, CJ Brandl
G3: Genes, Genomes, Genetics 8 (6), 1943-1957, 2018
Targeted sequencing reveals expanded genetic diversity of human transfer RNAs
MD Berg, DJ Giguere, JS Dron, JT Lant, J Genereaux, C Liao, J Wang, ...
RNA biology 16 (11), 1574-1585, 2019
Acceptor stem differences contribute to species-specific use of yeast and human tRNA-Ser
MD Berg, J Genereaux, Y Zhu, S Mian, GB Gloor, CJ Brandl
Genes 9 (12), 612, 2018
The amino acid substitution affects cellular response to mistranslation
MD Berg, Y Zhu, BY Ruiz, R Loll-Krippleber, J Isaacson, BJ San Luis, ...
G3: Genes, Genomes, Genetics 11 (10), jkab218, 2021
Mistranslating tRNA identifies a deleterious S213P mutation in the Saccharomyces cerevisiae eco1-1 allele
Y Zhu, MD Berg, P Yang, R Loll-Krippleber, GW Brown, CJ Brandl
Biochemistry and Cell Biology 98 (5), 624-630, 2020
Sfp1 links TORC1 and cell growth regulation to the yeast SAGA‐complex component Tra1 in response to polyQ proteotoxicity
Y Jiang, MD Berg, J Genereaux, K Ahmed, ML Duennwald, CJ Brandl, ...
Traffic 20 (4), 267-283, 2019
Regulating expression of mistranslating tRNAs by readthrough RNA polymerase II transcription
MD Berg, JR Isaacson, E Cozma, J Genereaux, P Lajoie, J Villén, ...
ACS Synthetic Biology 10 (11), 3177-3189, 2021
Chemical-Genetic Interactions with the Proline Analog L-Azetidine-2-Carboxylic Acid in Saccharomyces cerevisiae
MD Berg, Y Zhu, J Isaacson, J Genereaux, R Loll-Krippleber, GW Brown, ...
G3: Genes, Genomes, Genetics 10 (12), 4335-4345, 2020
A novel mistranslating tRNA model in Drosophila melanogaster has diverse, sexually dimorphic effects
JR Isaacson, MD Berg, B Charles, J Jagiello, J Villén, CJ Brandl, ...
G3: Genes, Genomes, Genetics 12 (5), jkac035, 2022
The SAGA and NuA4 component Tra1 regulates Candida albicans drug resistance and pathogenesis
I Razzaq, MD Berg, Y Jiang, J Genereaux, D Uthayakumar, GH Kim, ...
Genetics 219 (2), iyab131, 2021
Genetic background and mistranslation frequency determine the impact of mistranslating tRNA-Ser(UGG)
MD Berg, Y Zhu, R Loll-Krippleber, BJ San Luis, J Genereaux, C Boone, ...
G3: Genes, Genomes, Genetics, 2022
Tra1 controls the transcriptional landscape of the aging cell
KA Bari, MD Berg, J Genereaux, CJ Brandl, P Lajoie
bioRxiv, 2022
Implications and Applications of Transfer RNA Variants that Mistranslate the Genetic Code
MD Berg
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