| Cerebral cavernous malformations arise from endothelial gain of MEKK3–KLF2/4 signalling Z Zhou, AT Tang, WY Wong, S Bamezai, LM Goddard, R Shenkar, S Zhou, ... Nature 532 (7597), 122-126, 2016 | 284 | 2016 |
| Endothelial TLR4 and the microbiome drive cerebral cavernous malformations AT Tang, JP Choi, JJ Kotzin, Y Yang, CC Hong, N Hobson, R Girard, ... Nature 545 (7654), 305-310, 2017 | 282 | 2017 |
| PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism AA Ren, DA Snellings, YS Su, CC Hong, M Castro, AT Tang, MR Detter, ... Nature 594 (7862), 271-276, 2021 | 120 | 2021 |
| Familial cerebral cavernous malformations A Zafar, SA Quadri, M Farooqui, A Ikram, M Robinson, BL Hart, ... Stroke 50 (5), 1294-1301, 2019 | 109 | 2019 |
| Distinct cellular roles for PDCD10 define a gut-brain axis in cerebral cavernous malformation AT Tang, KR Sullivan, CC Hong, LM Goddard, A Mahadevan, A Ren, ... Science translational medicine 11 (520), eaaw3521, 2019 | 62 | 2019 |
| Vascular anomalies caused by abnormal signaling within endothelial cells: targets for novel therapies HL Nguyen, LM Boon, M Vikkula Seminars in interventional radiology 34 (03), 233-238, 2017 | 58 | 2017 |
| Inhibition of carcinoma cell motility by epoxyeicosatrienoic acid (EET) antagonists K Nithipatikom, DM Brody, AT Tang, VL Manthati, JR Falck, CL Williams, ... Cancer science 101 (12), 2629-2636, 2010 | 54 | 2010 |
| Comprehensive transcriptome analysis of cerebral cavernous malformation across multiple species and genotypes J Koskimäki, R Girard, Y Li, L Saadat, HA Zeineddine, R Lightle, T Moore, ... JCI insight 4 (3), 2019 | 44 | 2019 |
| ROCK1 feedback regulation of the upstream small GTPase RhoA AT Tang, WB Campbell, K Nithipatikom Cellular signalling 24 (7), 1375-1380, 2012 | 43 | 2012 |
| Cannabinoid receptor type 1 (CB1) activation inhibits small GTPase RhoA activity and regulates motility of prostate carcinoma cells K Nithipatikom, AD Gomez-Granados, AT Tang, AW Pfeiffer, CL Williams, ... Endocrinology 153 (1), 29-41, 2012 | 43 | 2012 |
| Genetic blockade of lymphangiogenesis does not impair cardiac function after myocardial infarction TCS Keller, L Lim, SV Shewale, K McDaid, Í Martí-Pàmies, AT Tang, ... The Journal of Clinical Investigation 131 (20), 2021 | 35 | 2021 |
| Cerebral cavernous malformations are driven by ADAMTS5 proteolysis of versican CC Hong, AT Tang, MR Detter, JP Choi, R Wang, X Yang, AA Guerrero, ... Journal of Experimental Medicine 217 (10), e20200140, 2020 | 31 | 2020 |
| Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma SP Polster, A Sharma, C Tanes, AT Tang, P Mericko, Y Cao, ... Nature communications 11 (1), 2659, 2020 | 30 | 2020 |
| Micro-computed tomography in murine models of cerebral cavernous malformations as a paradigm for brain disease R Girard, HA Zeineddine, C Orsbon, H Tan, T Moore, N Hobson, ... Journal of neuroscience methods 271, 14-24, 2016 | 29 | 2016 |
| Transcriptome clarifies mechanisms of lesion genesis versus progression in models of Ccm3 cerebral cavernous malformations J Koskimäki, D Zhang, Y Li, L Saadat, T Moore, R Lightle, SP Polster, ... Acta Neuropathologica Communications 7, 1-15, 2019 | 28 | 2019 |
| Phenotypic characterization of murine models of cerebral cavernous malformations HA Zeineddine, R Girard, L Saadat, L Shen, R Lightle, T Moore, Y Cao, ... Laboratory Investigation 99 (3), 319-330, 2019 | 24 | 2019 |
| Cerebral cavernous malformations arise independent of the heart of glass receptor X Zheng, F Riant, F Bergametti, CD Myers, AT Tang, B Kleaveland, W Pan, ... Stroke 45 (5), 1505-1509, 2014 | 22 | 2014 |
| RGS10 shapes the hemostatic response to injury through its differential effects on intracellular signaling by platelet agonists P Ma, S Gupta, S Sampietro, D DeHelian, V Tutwiler, A Tang, TJ Stalker, ... Blood Advances 2 (16), 2145-2155, 2018 | 19 | 2018 |
| Mouse placenta fetal macrophages arise from endothelial cells outside the placenta X Chen, AT Tang, J Tober, J Yang, NA Leu, S Sterling, M Chen, Y Yang, ... Developmental cell 57 (23), 2652-2660. e3, 2022 | 6 | 2022 |
| SARS-CoV-2 infection of olfactory epithelial cells and neurons drives acute lung injury and lethal COVID-19 in mice AT Tang, DW Buchholz, KM Szigety, B Imbhiaka, S Gao, M Frankfurter, ... bioRxiv, 2021.12. 04.471245, 2021 | 6 | 2021 |
