Rapid discovery of potent siRNA-containing lipid nanoparticles enabled by controlled microfluidic formulation D Chen, KT Love, Y Chen, AA Eltoukhy, C Kastrup, G Sahay, A Jeon, ... Journal of the American Chemical Society 134 (16), 6948-6951, 2012 | 540 | 2012 |
Self-propelled particles that transport cargo through flowing blood and halt hemorrhage JR Baylis, JH Yeon, MH Thomson, A Kazerooni, X Wang, AE St. John, ... Science advances 1 (9), e1500379, 2015 | 216 | 2015 |
Threshold response of initiation of blood coagulation by tissue factor in patterned microfluidic capillaries is controlled by shear rate F Shen, CJ Kastrup, Y Liu, RF Ismagilov Arteriosclerosis, thrombosis, and vascular biology 28 (11), 2035-2041, 2008 | 153 | 2008 |
Nanoparticulate cellular patches for cell-mediated tumoritropic delivery H Cheng, CJ Kastrup, R Ramanathan, DJ Siegwart, M Ma, SR Bogatyrev, ... ACS nano 4 (2), 625-631, 2010 | 152 | 2010 |
Painting blood vessels and atherosclerotic plaques with an adhesive drug depot CJ Kastrup, M Nahrendorf, JL Figueiredo, H Lee, ... Proceedings of the National Academy of Sciences 109 (52), 21444-21449, 2012 | 140 | 2012 |
Remotely activated protein-producing nanoparticles A Schroeder, MS Goldberg, C Kastrup, Y Wang, S Jiang, BJ Joseph, ... Nano letters 12 (6), 2685-2689, 2012 | 133 | 2012 |
Spatial localization of bacteria controls coagulation of human blood by'quorum acting' CJ Kastrup, JQ Boedicker, AP Pomerantsev, M Moayeri, Y Bian, ... Nature chemical biology 4 (12), 742-750, 2008 | 121 | 2008 |
Stem cell membrane engineering for cell rolling using peptide conjugation and tuning of cell–selectin interaction kinetics H Cheng, M Byrska-Bishop, CT Zhang, CJ Kastrup, NS Hwang, AK Tai, ... Biomaterials 33 (20), 5004-5012, 2012 | 113 | 2012 |
Fibrin is a critical regulator of neutrophil effector function at the oral mucosal barrier LM Silva, AD Doyle, T Greenwell-Wild, N Dutzan, CL Tran, L Abusleme, ... Science 374 (6575), eabl5450, 2021 | 110 | 2021 |
Modular chemical mechanism predicts spatiotemporal dynamics of initiation in the complex network of hemostasis CJ Kastrup, MK Runyon, F Shen, RF Ismagilov Proceedings of the National Academy of Sciences 103 (43), 15747-15752, 2006 | 97 | 2006 |
Effects of shear rate on propagation of blood clotting determined using microfluidics and numerical simulations MK Runyon, CJ Kastrup, BL Johnson-Kerner, TG Van Ha, RF Ismagilov Journal of the American Chemical Society 130 (11), 3458-3464, 2008 | 79 | 2008 |
Diatom frustule silica exhibits superhydrophilicity and superhemophilicity J Lee, HA Lee, M Shin, LJ Juang, CJ Kastrup, GM Go, H Lee ACS nano 14 (4), 4755-4766, 2020 | 65 | 2020 |
Defects in phosphate acquisition and storage influence virulence of Cryptococcus neoformans M Kretschmer, E Reiner, G Hu, N Tam, DL Oliveira, M Caza, JH Yeon, ... Infection and immunity 82 (7), 2697-2712, 2014 | 59 | 2014 |
Characterization of the threshold response of initiation of blood clotting to stimulus patch size CJ Kastrup, F Shen, MK Runyon, RF Ismagilov Biophysical journal 93 (8), 2969-2977, 2007 | 57 | 2007 |
Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage G Bao, Q Gao, M Cau, N Ali-Mohamad, M Strong, S Jiang, Z Yang, ... Nature Communications 13 (1), 5035, 2022 | 53 | 2022 |
Propagation of blood clotting in the complex biochemical network of hemostasis is described by a simple mechanism MK Runyon, BL Johnson-Kerner, CJ Kastrup, TG Van Ha, RF Ismagilov Journal of the American Chemical Society 129 (22), 7014-7015, 2007 | 53 | 2007 |
Coagulation factor XIIIa is inactivated by plasmin WS Hur, N Mazinani, XJD Lu, HM Britton, JR Byrnes, AS Wolberg, ... Blood, The Journal of the American Society of Hematology 126 (20), 2329-2337, 2015 | 51 | 2015 |
Comparison of DLin-MC3-DMA and ALC-0315 for siRNA delivery to hepatocytes and hepatic stellate cells F Ferraresso, AW Strilchuk, LJ Juang, LG Poole, JP Luyendyk, CJ Kastrup Molecular pharmaceutics 19 (7), 2175-2182, 2022 | 48 | 2022 |
Rivaroxaban and apixaban induce clotting factor Xa fibrinolytic activity RLR Carter, K Talbot, WS Hur, SC Meixner, JG Van Der Gugten, ... Journal of Thrombosis and Haemostasis 16 (11), 2276-2288, 2018 | 47 | 2018 |
The evolution of factor XI and the kallikrein-kinin system MB Ponczek, A Shamanaev, A LaPlace, SK Dickeson, P Srivastava, ... Blood advances 4 (24), 6135-6147, 2020 | 41 | 2020 |