| High-quality binary protein interaction map of the yeast interactome network H Yu, P Braun, MA Yıldırım, I Lemmens, K Venkatesan, J Sahalie, ... Science 322 (5898), 104-110, 2008 | 1681 | 2008 |
| First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement J Tabernero, GI Shapiro, PM LoRusso, A Cervantes, GK Schwartz, ... Cancer discovery 3 (4), 406-417, 2013 | 738 | 2013 |
| JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16 SW Oh, A Mukhopadhyay, N Svrzikapa, F Jiang, RJ Davis, ... Proceedings of the National Academy of Sciences 102 (12), 4494-4499, 2005 | 622 | 2005 |
| Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans D Dupuy, N Bertin, CA Hidalgo, K Venkatesan, D Tu, D Lee, J Rosenberg, ... Nature biotechnology 25 (6), 663-668, 2007 | 353 | 2007 |
| Next-generation sequencing to generate interactome datasets H Yu, L Tardivo, S Tam, E Weiner, F Gebreab, C Fan, N Svrzikapa, ... Nature methods 8 (6), 478-480, 2011 | 312 | 2011 |
| Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides N Iwamoto, DCD Butler, N Svrzikapa, S Mohapatra, I Zlatev, DWY Sah, ... Nature biotechnology 35 (9), 845-851, 2017 | 275 | 2017 |
| An antibiotic selection marker for nematode transgenesis R Giordano-Santini, S Milstein, N Svrzikapa, D Tu, R Johnsen, D Baillie, ... nature methods 7 (9), 721-723, 2010 | 87 | 2010 |
| 'Edgetic' perturbation of a C. elegans BCL2 ortholog M Dreze, B Charloteaux, S Milstein, PO Vidalain, MA Yildirim, Q Zhong, ... Nature methods 6 (11), 843-849, 2009 | 85 | 2009 |
| 'Edgetic' perturbation of a C. elegans BCL2 ortholog M Dreze, B Charloteaux, S Milstein, PO Vidalain, MA Yildirim, Q Zhong, ... Nature methods 6 (11), 843-849, 2009 | 85 | 2009 |
| Chiral control D Butler, N Iwamoto, N Svrzikapa, GL Verdine, I ZLATEV US Patent 9,982,257, 2018 | 78 | 2018 |
| In vivo quantification of formulated and chemically modified small interfering RNA by heating-in-Triton quantitative reverse transcription polymerase chain reaction … Y Landesman, N Svrzikapa, A Cognetta, X Zhang, BR Bettencourt, ... Silence 1, 1-14, 2010 | 56 | 2010 |
| Phase I dose-escalation study of ALN-VSP02, a novel RNAi therapeutic for solid tumors with liver involvement. A Cervantes, M Alsina, J Tabernero, JR Infante, P LoRusso, G Shapiro, ... Journal of Clinical Oncology 29 (15_suppl), 3025-3025, 2011 | 50 | 2011 |
| Meena; Standley, SM; Lu, G.; Apponi, LH; et al. Control of phosphorothioate stereochemistry substantially increases the efficacy of antisense oligonucleotides N Iwamoto, DCD Butler, N Svrzikapa, S Mohapatra, I Zlatev, DWY Sah Nat. Biotechnol 35 (9), 845-851, 2017 | 45 | 2017 |
| Meena, SM Standley, G. Lu, LH Apponi, M. Frank-Kamenetsky, JJ Zhang, C. Vargeese, GL Verdine, Control of phosphorothioate stereochemistry substantially increases the efficacy … N Iwamoto, DCD Butler, N Svrzikapa, S Mohapatra, I Zlatev, DWY Sah Nat. Biotechnol 35 (9), 2017 | 40 | 2017 |
| Bloom syndrome ortholog HIM-6 maintains genomic stability in C. elegans MM Grabowski, N Svrzikapa, HA Tissenbaum Mechanisms of ageing and development 126 (12), 1314-1321, 2005 | 36 | 2005 |
| Chiral control DCD Butler, N Iwamoto, N Svrzikapa, GL Verdine, I Zlatev US Patent 10,590,413, 2020 | 28 | 2020 |
| Chiral design D Butler, N Iwamoto, N Svrzikapa, GL Verdine, I Zlatev US Patent 10,160,969, 2018 | 26 | 2018 |
| Oligonucleotide compositions and methods thereof C Vargeese, N Svrzikapa, S Mohapatra, CJ Francis, GL Verdine, ... US Patent 10,479,995, 2019 | 23 | 2019 |
| First-in-humans trial of an RNA interference therapeutic targeting VEGF and KSP in cancer patients with liver involvement. Cancer Discov 3 (4): 406–417 J Tabernero, GI Shapiro, PM LoRusso, A Cervantes, GK Schwartz, ... CD-12-0429, 2013 | 23 | 2013 |
| Large-scale RACE approach for proactive experimental definition of C. elegans ORFeome K Salehi-Ashtiani, C Lin, T Hao, Y Shen, D Szeto, X Yang, L Ghamsari, ... Genome Research 19 (12), 2334-2342, 2009 | 19 | 2009 |
Gregory VerdineProfessor of Stem Cell and Regenerative Biology, Harvard UniversityVerified email at harvard.edu
