| Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase A Rossi, P Kapahi, G Natoli, T Takahashi, Y Chen, M Karin, MG Santoro Nature 403 (6765), 103-108, 2000 | 1635 | 2000 |
| Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway P Kapahi, BM Zid, T Harper, D Koslover, V Sapin, S Benzer Current biology 14 (10), 885-890, 2004 | 1565 | 2004 |
| MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation RM Laberge, YU Sun, AV Orjalo, CK Patil, A Freund, L Zhou, SC Curran, ... Nature cell biology 17 (8), 1049-1061, 2015 | 994 | 2015 |
| From discoveries in ageing research to therapeutics for healthy ageing J Campisi, P Kapahi, GJ Lithgow, S Melov, JC Newman, E Verdin Nature 571 (7764), 183-192, 2019 | 917 | 2019 |
| With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging P Kapahi, D Chen, AN Rogers, SD Katewa, PWL Li, EL Thomas, L Kockel Cell metabolism 11 (6), 453-465, 2010 | 780 | 2010 |
| 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila BM Zid, AN Rogers, SD Katewa, MA Vargas, MC Kolipinski, TA Lu, ... Cell 139 (1), 149-160, 2009 | 602 | 2009 |
| Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans KZ Pan, JE Palter, AN Rogers, A Olsen, D Chen, GJ Lithgow, P Kapahi Aging cell 6 (1), 111-119, 2007 | 565 | 2007 |
| Cellular senescence: a link between cancer and age-related degenerative disease? J Campisi, JK Andersen, P Kapahi, S Melov Seminars in cancer biology 21 (6), 354-359, 2011 | 497 | 2011 |
| The role of advanced glycation end products in aging and metabolic diseases: bridging association and causality J Chaudhuri, Y Bains, S Guha, A Kahn, D Hall, N Bose, A Gugliucci, ... Cell metabolism 28 (3), 337-352, 2018 | 462 | 2018 |
| Inhibition of NF-κB activation by arsenite through reaction with a critical cysteine in the activation loop of IκB kinase P Kapahi, T Takahashi, G Natoli, SR Adams, Y Chen, RY Tsien, M Karin Journal of Biological Chemistry 275 (46), 36062-36066, 2000 | 453 | 2000 |
| Positive correlation between mammalian life span and cellular resistance to stress P Kapahi, ME Boulton, TBL Kirkwood Free Radical Biology and Medicine 26 (5-6), 495-500, 1999 | 411 | 1999 |
| Dietary restriction and lifespan: Lessons from invertebrate models P Kapahi, M Kaeberlein, M Hansen Ageing research reviews 39, 3-14, 2017 | 315 | 2017 |
| Late‐life rapamycin treatment reverses age‐related heart dysfunction JM Flynn, MN O'Leary, CA Zambataro, EC Academia, MP Presley, ... Aging cell 12 (5), 851-862, 2013 | 314 | 2013 |
| Allocrine modulation of feeding behavior by the sex peptide of Drosophila GB Carvalho, P Kapahi, DJ Anderson, S Benzer Current Biology 16 (7), 692-696, 2006 | 301 | 2006 |
| HIF-1 Modulates Dietary Restriction-Mediated Lifespan Extension via IRE-1 in Caenorhabditis elegans D Chen, EL Thomas, P Kapahi PLoS genetics 5 (5), e1000486, 2009 | 300 | 2009 |
| Skyline for small molecules: a unifying software package for quantitative metabolomics KJ Adams, B Pratt, N Bose, LG Dubois, L St. John-Williams, KM Perrott, ... Journal of proteome research 19 (4), 1447-1458, 2020 | 285 | 2020 |
| SIRT7 represses Myc activity to suppress ER stress and prevent fatty liver disease J Shin, M He, Y Liu, S Paredes, L Villanova, K Brown, X Qiu, N Nabavi, ... Cell reports 5 (3), 654-665, 2013 | 277 | 2013 |
| Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype RM Laberge, L Zhou, MR Sarantos, F Rodier, A Freund, PLJ de Keizer, ... Aging cell 11 (4), 569-578, 2012 | 236 | 2012 |
| Detection of a circulating form of vascular cell adhesion molecule-1: raised levels in rheumatoid arthritis and systemic lupus erythematosus SM Wellicome, P Kapahi, JC Mason, Y Lebranchu, H Yarwood, ... Clinical & Experimental Immunology 92 (3), 412-418, 1993 | 204 | 1993 |
| Oxidative stress and gene expression: the AP-1 and NF-kappaB connections M Karin, T Takahashi, P Kapahi, M Delhase, Y Chen, C Makris, V Baud, ... BIOFACTORS-OXFORD THEN AMSTERDAM- 15 (2/4), 87-90, 2001 | 196 | 2001 |
Gordon LithgowVerified email at buckinstitute.org
