Ian Simpson
Ian Simpson
Reader in Biological Informatics, School of Informatics, University of Edinburgh
Verified email at ed.ac.uk - Homepage
Cited by
Cited by
Pax6; a pleiotropic player in development
TI Simpson, DJ Price
Bioessays 24 (11), 1041-1051, 2002
Long-range downstream enhancers are essential for Pax6 expression
DA Kleinjan, A Seawright, S Mella, CB Carr, DA Tyas, TI Simpson, ...
Developmental biology 299 (2), 563-581, 2006
Neurons and neuronal activity control gene expression in astrocytes to regulate their development and metabolism
P Hasel, O Dando, Z Jiwaji, P Baxter, AC Todd, S Heron, NM Márkus, ...
Nature Communications 8, 15132, 2017
The motility of glioblastoma tumour cells is modulated by intracellular cofilin expression in a concentration‐dependent manner
CT Yap, TI Simpson, T Pratt, DJ Price, SK Maciver
Cell motility and the cytoskeleton 60 (3), 153-165, 2005
Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect …
M Manuel, PA Georgala, CB Carr, S Chanas, DA Kleinjan, B Martynoga, ...
Development 134 (3), 545-555, 2007
Consolidation and translation regulation
S Gal-Ben-Ari, JW Kenney, H Ounalla-Saad, E Taha, O David, D Levitan, ...
Learning & Memory 19 (9), 410-422, 2012
The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse
T Pratt, NMML Tian, TI Simpson, JO Mason, DJ Price
Development 131 (15), 3773-3784, 2004
Pax6 Exerts Regional Control of Cortical Progenitor Proliferation via Direct Repression of Cdk6 and Hypophosphorylation of pRb
D Mi, CB Carr, PA Georgala, YT Huang, MN Manuel, E Jeanes, E Niisato, ...
Neuron 78 (2), 269-284, 2013
Merged consensus clustering to assess and improve class discovery with microarray data
TI Simpson, JD Armstrong, A Jarman
BMC bioinformatics 11 (1), 590, 2010
The gene regulatory cascade linking proneural specification with differentiation in Drosophila sensory neurons
TI Simpson, S Cachero, PI Zur Lage, L Ma, FG Newton, EE Holohan, ...
PLoS biology 9 (1), e1000568, 2011
Disruption of early events in thalamocortical tract formation in mice lacking the transcription factors Pax6 or Foxg1
T Pratt, JC Quinn, TI Simpson, JD West, JO Mason, DJ Price
Journal of Neuroscience 22 (19), 8523-8531, 2002
Normal ventral telencephalic expression of Pax6 is required for normal development of thalamocortical axons in embryonic mice
TI Simpson, T Pratt, JO Mason, DJ Price
Neural Dev 4, 19, 2009
Regulation of the Pax6: Pax6 (5a) mRNA ratio in the developing mammalian brain
J Pinson, JO Mason, TI Simpson, DJ Price
BMC developmental biology 5 (1), 13, 2005
Positive autoregulation of the transcription factor Pax6 in response to increased levels of either of its major isoforms, Pax6 or Pax6 (5a), in cultured cells
J Pinson, TI Simpson, JO Mason, DJ Price
BMC developmental biology 6 (1), 25, 2006
Network Analyses Reveal Novel Aspects of ALS Pathogenesis
M Sanhueza, A Chai, C Smith, BA McCray, TI Simpson, JP Taylor, ...
PLoS genetics 11 (3), e1005107-e1005107, 2015
NMDA receptor-dependent regulation of miRNA expression and association with Argonaute during LTP in vivo
B Pai, T Siripornmongcolchai, B Berentsen, A Pakzad, C Vieuille, ...
Frontiers in cellular neuroscience 7, 2013
Functional conservation of Pax6 regulatory elements in humans and mice demonstrated with a novel transgenic reporter mouse
D Tyas, TI Simpson, C Carr, D Kleinjan, V van Heyningen, J Mason, ...
BMC developmental biology 6 (1), 21, 2006
Bio:: Homology:: InterologWalk-A Perl module to build putative protein-protein interaction networks through interolog mapping
G Gallone, TI Simpson, JD Armstrong, A Jarman
BMC bioinformatics 12 (1), 289, 2011
Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons
J Qiu, J McQueen, B Bilican, O Dando, D Magnani, K Punovuori, ...
eLife 5, e20337, 2016
Expression of mRNA Encoding Mcu and Other Mitochondrial Calcium Regulatory Genes Depends on Cell Type, Neuronal Subtype, and Ca2+ Signaling
NM Markus, P Hasel, J Qiu, KFS Bell, S Heron, PC Kind, O Dando, ...
PloS one 11 (2), e0148164, 2016
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