Michael Costanzo
Michael Costanzo
Verified email at utoronto.ca
TitleCited byYear
The genetic landscape of a cell
M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ...
science 327 (5964), 425-431, 2010
19082010
CDK activity antagonizes Whi5, an inhibitor of G1/S transcription in yeast
M Costanzo, JL Nishikawa, X Tang, JS Millman, O Schub, K Breitkreuz, ...
Cell 117 (7), 899-913, 2004
4212004
A global genetic interaction network maps a wiring diagram of cellular function
M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ...
Science 353 (6306), aaf1420, 2016
4022016
Dissecting DNA damage response pathways by analysing protein localization and abundance changes during DNA replication stress
JM Tkach, A Yimit, AY Lee, M Riffle, M Costanzo, D Jaschob, JA Hendry, ...
Nature cell biology 14 (9), 966, 2012
3072012
The Shwachman-Bodian-Diamond syndrome protein mediates translational activation of ribosomes in yeast
TF Menne, B Goyenechea, N Sánchez-Puig, CC Wong, LM Tonkin, ...
Nature genetics 39 (4), 486, 2007
2842007
Quantitative analysis of fitness and genetic interactions in yeast on a genome scale
A Baryshnikova, M Costanzo, Y Kim, H Ding, J Koh, K Toufighi, JY Youn, ...
Nature methods 7 (12), 1017, 2010
2782010
Systematic mapping of genetic interaction networks
SJ Dixon, M Costanzo, A Baryshnikova, B Andrews, C Boone
Annual review of genetics 43, 601-625, 2009
2712009
Systematic exploration of essential yeast gene function with temperature-sensitive mutants
Z Li, FJ Vizeacoumar, S Bahr, J Li, J Warringer, FS Vizeacoumar, R Min, ...
Nature biotechnology 29 (4), 361, 2011
2602011
Widespread expansion of protein interaction capabilities by alternative splicing
X Yang, J Coulombe-Huntington, S Kang, GM Sheynkman, T Hao, ...
Cell 164 (4), 805-817, 2016
2072016
Ubiquitin-related modifier Urm1 acts as a sulphur carrier in thiolation of eukaryotic transfer RNA
S Leidel, PGA Pedrioli, T Bucher, R Brost, M Costanzo, A Schmidt, ...
Nature 458 (7235), 228, 2009
2062009
Systematic exploration of synergistic drug pairs
M Cokol, HN Chua, M Tasan, B Mutlu, ZB Weinstein, Y Suzuki, ME Nergiz, ...
Molecular systems biology 7 (1), 2011
1952011
Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes Shwachman-Diamond syndrome
AJ Finch, C Hilcenko, N Basse, LF Drynan, B Goyenechea, TF Menne, ...
Genes & development 25 (9), 917-929, 2011
1932011
An integrated approach to characterize genetic interaction networks in yeast metabolism
B Szappanos, K Kovács, B Szamecz, F Honti, M Costanzo, ...
Nature genetics 43 (7), 656, 2011
1772011
The interaction network of the chaperonin CCT
C Dekker, PC Stirling, EA McCormack, H Filmore, A Paul, RL Brost, ...
The EMBO journal 27 (13), 1827-1839, 2008
1762008
Global gene deletion analysis exploring yeast filamentous growth
O Ryan, RS Shapiro, CF Kurat, D Mayhew, A Baryshnikova, B Chin, ...
Science 337 (6100), 1353-1356, 2012
1622012
Molecular chaperone Hsp90 stabilizes Pih1/Nop17 to maintain R2TP complex activity that regulates snoRNA accumulation
R Zhao, Y Kakihara, A Gribun, J Huen, G Yang, M Khanna, M Costanzo, ...
J Cell Biol 180 (3), 563-578, 2008
1602008
Synthetic genetic array (SGA) analysis in Saccharomyces cerevisiae and Schizosaccharomyces pombe
A Baryshnikova, M Costanzo, S Dixon, FJ Vizeacoumar, CL Myers, ...
Methods in enzymology 470, 145-179, 2010
1462010
Computationally driven, quantitative experiments discover genes required for mitochondrial biogenesis
DC Hess, CL Myers, C Huttenhower, MA Hibbs, AP Hayes, J Paw, ...
PLoS genetics 5 (3), e1000407, 2009
1372009
Bringing order to protein disorder through comparative genomics and genetic interactions
J Bellay, S Han, M Michaut, TH Kim, M Costanzo, BJ Andrews, C Boone, ...
Genome biology 12 (2), R14, 2011
1192011
Charting the genetic interaction map of a cell
M Costanzo, A Baryshnikova, CL Myers, B Andrews, C Boone
Current opinion in biotechnology 22 (1), 66-74, 2011
1102011
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Articles 1–20