| Cognate memory CD4+ T cells generated with dendritic cell priming influence the expansion, trafficking, and differentiation of secondary CD8+ T cells and enhance tumor control ML Hwang, JR Lukens, TNJ Bullock The Journal of Immunology 179 (9), 5829-5838, 2007 | 729 | 2007 |
| CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature A Louveau, J Herz, MN Alme, AF Salvador, MQ Dong, KE Viar, SG Herod, ... Nature neuroscience 21 (10), 1380-1391, 2018 | 697 | 2018 |
| NLRP6 negatively regulates innate immunity and host defence against bacterial pathogens PK Anand, RKS Malireddi, JR Lukens, P Vogel, J Bertin, M Lamkanfi, ... Nature 488 (7411), 389-393, 2012 | 433 | 2012 |
| Mitochondria: diversity in the regulation of the NLRP3 inflammasome P Gurung, JR Lukens, TD Kanneganti Trends in molecular medicine 21 (3), 193-201, 2015 | 376 | 2015 |
| Dealing with danger in the CNS: the response of the immune system to injury SP Gadani, JT Walsh, JR Lukens, J Kipnis Neuron 87 (1), 47-62, 2015 | 312 | 2015 |
| Dietary modulation of the microbiome affects autoinflammatory disease JR Lukens, P Gurung, P Vogel, GR Johnson, RA Carter, DJ McGoldrick, ... Nature 516 (7530), 246-249, 2014 | 298 | 2014 |
| Emerging roles for the immune system in traumatic brain injury CA McKee, JR Lukens Frontiers in immunology 7, 231380, 2016 | 248 | 2016 |
| MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4 JT Walsh, S Hendrix, F Boato, I Smirnov, J Zheng, JR Lukens, S Gadani, ... The Journal of clinical investigation 125 (2), 699-714, 2015 | 216 | 2015 |
| Meningeal lymphatic dysfunction exacerbates traumatic brain injury pathogenesis AC Bolte, AB Dutta, ME Hurt, I Smirnov, MA Kovacs, CA McKee, ... Nature communications 11 (1), 4524, 2020 | 211 | 2020 |
| IL-1 family cytokines trigger sterile inflammatory disease JR Lukens, JM Gross, TD Kanneganti Frontiers in immunology 3, 33180, 2012 | 210 | 2012 |
| RIP1-driven autoinflammation targets IL-1α independently of inflammasomes and RIP3 JR Lukens, P Vogel, GR Johnson, MA Kelliher, Y Iwakura, M Lamkanfi, ... Nature 498 (7453), 224-227, 2013 | 173 | 2013 |
| Protective roles for caspase-8 and cFLIP in adult homeostasis R Weinlich, A Oberst, CP Dillon, LJ Janke, S Milasta, JR Lukens, ... Cell reports 5 (2), 340-348, 2013 | 166 | 2013 |
| Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis PJ Shaw, JR Lukens, S Burns, H Chi, MA McGargill, TD Kanneganti The Journal of Immunology 184 (9), 4610-4614, 2010 | 163 | 2010 |
| AIM2 inflammasome surveillance of DNA damage shapes neurodevelopment CR Lammert, EL Frost, CE Bellinger, AC Bolte, CA McKee, ME Hurt, ... Nature 580 (7805), 647-652, 2020 | 150 | 2020 |
| Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity PJ Shaw, MJ Barr, JR Lukens, MA McGargill, H Chi, TW Mak, ... Immunity 34 (1), 75-84, 2011 | 144 | 2011 |
| Innate immunity at the crossroads of healthy brain maturation and neurodevelopmental disorders KE Zengeler, JR Lukens Nature Reviews Immunology 21 (7), 454-468, 2021 | 142 | 2021 |
| Inflammasome-derived IL-1β regulates the production of GM-CSF by CD4+ T cells and γδ T cells JR Lukens, MJ Barr, DD Chaplin, H Chi, TD Kanneganti The Journal of Immunology 188 (7), 3107-3115, 2012 | 137 | 2012 |
| Intrahepatic IL-10 maintains NKG2A+ Ly49− liver NK cells in a functionally hyporesponsive state MG Lassen, JR Lukens, JS Dolina, MG Brown, YS Hahn The Journal of Immunology 184 (5), 2693-2701, 2010 | 134 | 2010 |
| Critical role for inflammasome-independent IL-1β production in osteomyelitis JR Lukens, JM Gross, C Calabrese, Y Iwakura, M Lamkanfi, P Vogel, ... Proceedings of the National Academy of Sciences 111 (3), 1066-1071, 2014 | 129 | 2014 |
| The NLRP12 sensor negatively regulates autoinflammatory disease by modulating interleukin-4 production in T cells JR Lukens, P Gurung, PJ Shaw, MJ Barr, MH Zaki, SA Brown, P Vogel, ... Immunity 42 (4), 654-664, 2015 | 115 | 2015 |
