Macromolecular modeling and design in Rosetta: recent methods and frameworks JK Leman, BD Weitzner, SM Lewis, J Adolf-Bryfogle, N Alam, RF Alford, ... Nature methods 17 (7), 665-680, 2020 | 570 | 2020 |
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors L Cao, I Goreshnik, B Coventry, JB Case, L Miller, L Kozodoy, RE Chen, ... Science 370 (6515), 426-431, 2020 | 562 | 2020 |
Design of protein-binding proteins from the target structure alone L Cao, B Coventry, I Goreshnik, B Huang, W Sheffler, JS Park, KM Jude, ... Nature 605 (7910), 551-560, 2022 | 223 | 2022 |
De novo design of luciferases using deep learning AHW Yeh, C Norn, Y Kipnis, D Tischer, SJ Pellock, D Evans, P Ma, ... Nature 614 (7949), 774-780, 2023 | 161 | 2023 |
Perturbing the energy landscape for improved packing during computational protein design JB Maguire, HK Haddox, D Strickland, SF Halabiya, B Coventry, JR Griffin, ... Proteins: Structure, Function, and Bioinformatics 89 (4), 436-449, 2021 | 96 | 2021 |
Improving de novo protein binder design with deep learning NR Bennett, B Coventry, I Goreshnik, B Huang, A Allen, D Vafeados, ... Nature Communications 14 (1), 2625, 2023 | 88 | 2023 |
Protein sequence optimization with a pairwise decomposable penalty for buried unsatisfied hydrogen bonds B Coventry, D Baker PLoS computational biology 17 (3), e1008061, 2021 | 24 | 2021 |
Robust de novo design of protein binding proteins from target structural information alone L Cao, B Coventry, I Goreshnik, B Huang, JS Park, KM Jude, I Marković, ... BioRxiv, 2021.09. 04.459002, 2021 | 14 | 2021 |
Computational design of a neutralizing antibody with picomolar binding affinity for all concerning SARS-CoV-2 variants BS Jeong, JS Cha, I Hwang, U Kim, J Adolf-Bryfogle, B Coventry, HS Cho, ... MAbs 14 (1), 2021601, 2022 | 13 | 2022 |
De novo design of protein homodimers containing tunable symmetric protein pockets DR Hicks, MA Kennedy, KA Thompson, M DeWitt, B Coventry, A Kang, ... Proceedings of the National Academy of Sciences 119 (30), e2113400119, 2022 | 13 | 2022 |
Randomized gates eliminate bias in sort‐seq assays BL Trippe, B Huang, EA DeBenedictis, B Coventry, N Bhattacharya, ... Protein Science 31 (9), e4401, 2022 | 7 | 2022 |
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors. bioRxiv [Preprint]. 2020 Aug 3. DOI: 10.1101/2020.08. 03.234914. Science 23 October 2020: Vol. 370, Issue 6515 L Cao, I Goreshnik, B Coventry, JB Case, L Miller, L Kozodoy, RE Chen, ... DOI 10, 426-431, 0 | 7 | |
Computational design of sequence-specific DNA-binding proteins CJ Glasscock, R Pecoraro, R McHugh, LA Doyle, W Chen, O Boivin, ... bioRxiv, 2023 | 6 | 2023 |
Designed Endocytosis-Triggering Proteins mediate Targeted Degradation B Huang, M Abedi, G Ahn, B Coventry, I Sappington, R Wang, ... BioRxiv, 2023 | 5 | 2023 |
Modulation of FGF pathway signaling and vascular differentiation using designed oligomeric assemblies NI Edman, RL Redler, A Phal, T Schlichthaerle, SR Srivatsan, A Etemadi, ... bioRxiv, 2023 | 4 | 2023 |
Small-molecule binding and sensing with a designed protein family GR Lee, SJ Pellock, C Norn, D Tischer, J Dauparas, I Anishchenko, ... bioRxiv, 2023.11. 01.565201, 2023 | 4 | 2023 |
De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles L An, M Said, L Tran, S Majumder, I Goreshnik, GR Lee, D Juergens, ... bioRxiv, 2023 | 3 | 2023 |
Design of Diverse Asymmetric Pockets in De Novo Homo-oligomeric Proteins SR Gerben, AJ Borst, DR Hicks, I Moczygemba, D Feldman, B Coventry, ... Biochemistry 62 (2), 358-368, 2023 | 3 | 2023 |
Blueprinting extendable nanomaterials with standardized protein blocks TF Huddy, Y Hsia, RD Kibler, J Xu, N Bethel, D Nagarajan, R Redler, ... Nature 627 (8005), 898-904, 2024 | 2 | 2024 |
De novo design of picomolar SARS-CoV-2 miniprotein inhibitors D Baker, L Cao, I Goreshnik, B Coventry, JB Case, L Miller, L Kozodoy, ... | 2 | 2020 |