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David J. Segal
David J. Segal
Verified email at ucdavis.edu
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Cited by
Year
Stimulation of homologous recombination through targeted cleavage by chimeric nucleases
M Bibikova, D Carroll, DJ Segal, JK Trautman, J Smith, YG Kim, ...
Molecular and cellular biology 21 (1), 289-297, 2001
8662001
Toward controlling gene expression at will: Specific regulation of the erbB-2/HER-2 promoter by using polydactyl zinc finger proteins constructed from modular …
RR Beerli, DJ Segal, B Dreier, CF Barbas III
Proceedings of the National Academy of Sciences 95 (25), 14628-14633, 1998
7991998
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases
M Szczepek, V Brondani, J Büchel, L Serrano, DJ Segal, T Cathomen
Nature biotechnology 25 (7), 786-793, 2007
6422007
Toward controlling gene expression at will: selection and design of zinc finger domains recognizing each of the 5′-GNN-3′ DNA target sequences
DJ Segal, B Dreier, RR Beerli, CF Barbas III
Proceedings of the National Academy of Sciences 96 (6), 2758-2763, 1999
5971999
Methods and compositions for using zinc finger endonucleases to enhance homologous recombination
M Liljedahl, S Aspland, D Segal
US Patent App. 10/395,816, 2003
5042003
Design of polydactyl zinc-finger proteins for unique addressing within complex genomes
Q Liu, DJ Segal, JB Ghiara, CF Barbas III
Proceedings of the National Academy of Sciences 94 (11), 5525-5530, 1997
4801997
Development of zinc finger domains for recognition of the 5′-ANN-3′ family of DNA sequences and their use in the construction of artificial transcription factors
B Dreier, RR Beerli, DJ Segal, JD Flippin, CF Barbas
Journal of Biological Chemistry 276 (31), 29466-29478, 2001
3952001
Keep your fingers off my DNA: protein–protein interactions mediated by C2H2 zinc finger domains
KJ Brayer, DJ Segal
Cell biochemistry and biophysics 50, 111-131, 2008
3792008
SRA-and SET-domain-containing proteins link RNA polymerase V occupancy to DNA methylation
LM Johnson, J Du, CJ Hale, S Bischof, S Feng, RK Chodavarapu, ...
Nature 507 (7490), 124-128, 2014
3222014
Development of zinc finger domains for recognition of the 5′-CNN-3′ family DNA sequences and their use in the construction of artificial transcription factors
B Dreier, RP Fuller, DJ Segal, CV Lund, P Blancafort, A Huber, B Koksch, ...
Journal of Biological Chemistry 280 (42), 35588-35597, 2005
2572005
Targeted DNA demethylation of the Arabidopsis genome using the human TET1 catalytic domain
J Gallego-Bartolomé, J Gardiner, W Liu, A Papikian, B Ghoshal, HY Kuo, ...
Proceedings of the National Academy of Sciences 115 (9), E2125-E2134, 2018
2542018
A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture
H O'Geen, IM Henry, MS Bhakta, JF Meckler, DJ Segal
Nucleic acids research 43 (6), 3389-3404, 2015
2522015
Design, construction and in vitro testing of zinc finger nucleases
D Carroll, JJ Morton, KJ Beumer, DJ Segal
Nature protocols 1 (3), 1329-1341, 2006
2492006
Evaluation of a modular strategy for the construction of novel polydactyl zinc finger DNA-binding proteins
DJ Segal, RR Beerli, P Blancafort, B Dreier, K Effertz, A Huber, B Koksch, ...
Biochemistry 42 (7), 2137-2148, 2003
2462003
Designing transcription factor architectures for drug discovery
P Blancafort, DJ Segal, CF Barbas
Molecular pharmacology 66 (6), 1361-1371, 2004
2262004
Custom zinc-finger nucleases for use in human cells
S Alwin, MB Gere, E Guhl, K Effertz, CF Barbas, DJ Segal, MD Weitzman, ...
Molecular Therapy 12 (4), 610-617, 2005
2162005
Quantitative analysis of TALE–DNA interactions suggests polarity effects
JF Meckler, MS Bhakta, MS Kim, R Ovadia, CH Habrian, A Zykovich, A Yu, ...
Nucleic acids research 41 (7), 4118-4128, 2013
2142013
Insights into the molecular recognition of the 5′-GNN-3′ family of DNA sequences by zinc finger domains
B Dreier, DJ Segal, CF Barbas III
Journal of molecular biology 303 (4), 489-502, 2000
2132000
dCas9-based epigenome editing suggests acquisition of histone methylation is not sufficient for target gene repression
H O’Geen, C Ren, CM Nicolet, AA Perez, J Halmai, VM Le, JP Mackay, ...
Nucleic acids research 45 (17), 9901-9916, 2017
2102017
Fusion proteins consisting of human immunodeficiency virus type 1 integrase and the designed polydactyl zinc finger protein E2C direct integration of viral DNA into specific sites
W Tan, K Zhu, DJ Segal, CF Barbas III, SA Chow
Journal of virology 78 (3), 1301-1313, 2004
1772004
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