Francis Szoka
Francis Szoka
Professor of Bioengineering and therapeutic sciences
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Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation
F Szoka, D Papahadjopoulos
Proceedings of the national academy of sciences 75 (9), 4194-4198, 1978
Designing dendrimers for biological applications
CC Lee, JA MacKay, JMJ Fréchet, FC Szoka
Nature biotechnology 23 (12), 1517-1526, 2005
Comparative properties and methods of preparation of lipid vesicles (liposomes)
F Szoka Jr, D Papahadjopoulos
Annual review of biophysics and bioengineering 9 (1), 467-508, 1980
Polyamidoamine cascade polymers mediate efficient transfection of cells in culture
J Haensler, FC Szoka Jr
Bioconjugate chemistry 4 (5), 372-379, 1993
Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes
F Olson, CA Hunt, FC Szoka, WJ Vail, D Papahadjopoulos
Biochimica et Biophysica Acta (BBA)-Biomembranes 557 (1), 9-23, 1979
Mechanism of DNA Release from Cationic Liposome/DNA Complexes Used in Cell Transfection,
Y Xu, FC Szoka
Biochemistry 35 (18), 5616-5623, 1996
In Vitro Gene Delivery by Degraded Polyamidoamine Dendrimers
MX Tang, CT Redemann, FC Szoka
Bioconjugate chemistry 7 (6), 703-714, 1996
Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes
ND Sonawane, FC Szoka, AS Verkman
Journal of Biological Chemistry 278 (45), 44826-44831, 2003
Method of encapsulating biologically active materials in lipid vesicles
DP Papahadjopoulos, FC Szoka Jr
US Patent 4,235,871, 1980
The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes
MX Tang, FC Szoka
Gene therapy 4 (8), 823-832, 1997
Mechanism of oligonucleotide release from cationic liposomes
O Zelphati, FC Szoka
Proceedings of the National Academy of Sciences 93 (21), 11493-11498, 1996
Activation of the complement system by synthetic DNA complexes: a potential barrier for intravenous gene delivery
C Plank, K Mechtler, FC Szoka Jr, E Wagner
Human gene therapy 7 (12), 1437-1446, 1996
A single dose of doxorubicin-functionalized bow-tie dendrimer cures mice bearing C-26 colon carcinomas
CC Lee, ER Gillies, ME Fox, SJ Guillaudeu, JMJ Fréchet, EE Dy, ...
Proceedings of the National Academy of Sciences 103 (45), 16649-16654, 2006
Soluble polymer carriers for the treatment of cancer: the importance of molecular architecture
ME Fox, FC Szoka, JMJ Fréchet
Accounts of chemical research 42 (8), 1141-1151, 2009
Lipid-based nanoparticles for nucleic acid delivery
W Li, FC Szoka
Pharmaceutical research 24 (3), 438-449, 2007
Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation
OL Padilla De Jesús, HR Ihre, L Gagne, JMJ Fréchet, FC Szoka
Bioconjugate chemistry 13 (3), 453-461, 2002
Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers
TB Wyman, F Nicol, O Zelphati, PV Scaria, C Plank, FC Szoka
Biochemistry 36 (10), 3008-3017, 1997
Nomenclature for synthetic gene delivery systems
PL Felgner, Y Barenholz, JP Behr, SH Cheng, P Cullis, L Huang, ...
Human gene therapy 8 (5), 511-512, 1997
Preparation of unilamellar liposomes of intermediate size (0.1–0.2 μm) by a combination of reverse phase evaporation and extrusion through polycarbonate membranes
F Szoka, F Olson, T Heath, W Vail, E Mayhew, D Papahadjopoulos
Biochimica et Biophysica Acta (BBA)-Biomembranes 601, 559-571, 1980
Chemical approaches to triggerable lipid vesicles for drug and gene delivery
X Guo, FC Szoka
Accounts of chemical research 36 (5), 335-341, 2003
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