Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ... Immunity 55 (2), 324-340. e8, 2022 | 206 | 2022 |
Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling SK Loganathan, K Schleicher, A Malik, R Quevedo, E Langille, K Teng, ... Science 367 (6483), 1264-1269, 2020 | 156 | 2020 |
Revisiting inconsistency in large pharmacogenomic studies Z Safikhani, P Smirnov, M Freeman, N El-Hachem, A She, Q Rene, ... F1000Research 5, 2016 | 115 | 2016 |
Somatic BRCA1/2 Recovery as a Resistance Mechanism After Exceptional Response to Poly (ADP-ribose) Polymerase Inhibition S Lheureux, JP Bruce, JV Burnier, K Karakasis, PA Shaw, BA Clarke, ... Journal of clinical oncology 35 (11), 1240-1249, 2017 | 92 | 2017 |
Activating mutations affecting the Dbl homology domain of SOS2 cause Noonan syndrome V Cordeddu, JC Yin, C Gunnarsson, C Virtanen, S Drunat, F Lepri, ... Human mutation 36 (11), 1080-1087, 2015 | 87 | 2015 |
Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long-and short-term survivors SYC Yang, S Lheureux, K Karakasis, JV Burnier, JP Bruce, DL Clouthier, ... Genome medicine 10, 1-17, 2018 | 82 | 2018 |
Gene isoforms as expression-based biomarkers predictive of drug response in vitro Z Safikhani, P Smirnov, KL Thu, J Silvester, N El-Hachem, R Quevedo, ... Nature communications 8 (1), 1126, 2017 | 70 | 2017 |
Assessment of pharmacogenomic agreement Z Safikhani, N El-Hachem, R Quevedo, P Smirnov, A Goldenberg, ... F1000Research 5, 2016 | 38 | 2016 |
The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity S Lukhele, D Abd Rabbo, M Guo, J Shen, HJ Elsaesser, R Quevedo, ... Immunity 55 (12), 2369-2385. e10, 2022 | 37 | 2022 |
Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy GM Boukhaled, R Gadalla, HJ Elsaesser, D Abd-Rabbo, R Quevedo, ... Nature immunology 23 (8), 1273-1283, 2022 | 23 | 2022 |
Assessment of genetic drift in large pharmacogenomic studies R Quevedo, P Smirnov, D Tkachuk, C Ho, N El-Hachem, Z Safikhani, ... Cell systems 11 (4), 393-401. e2, 2020 | 19 | 2020 |
An integrative DNA sequencing and methylation panel to assess mismatch repair deficiency LE Oldfield, T Li, A Tone, M Aronson, M Edwards, S Holter, R Quevedo, ... The Journal of Molecular Diagnostics 23 (2), 242-252, 2021 | 13 | 2021 |
Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor R Quevedo, A Spreafico, J Bruce, A Danesh, S El Ghamrasni, A Giesler, ... Genome Medicine 12, 1-15, 2020 | 12 | 2020 |
Heterogeneous alteration of the ERBB3–MYC axis associated with MEK inhibitor resistance in a KRAS-mutated low-grade serous ovarian cancer patient I Colombo, S Garg, A Danesh, J Bruce, P Shaw, Q Tan, R Quevedo, ... Molecular Case Studies 5 (6), a004341, 2019 | 7 | 2019 |
Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer S El Ghamrasni, R Quevedo, J Hawley, P Mazrooei, Y Hanna, I Cirlan, ... Molecular Cancer Research 20 (1), 102-113, 2022 | 3 | 2022 |
EHMT2/G9a-Inhibition Reprograms Cancer-Associated Fibroblasts (CAFs) to a More Differentiated, Less Proliferative and Invasive State NC Wu, R Quevedo, M Nurse, K Hezaveh, H Liu, F Sun, J Muffat, Y Sun, ... bioRxiv, 2023.07. 17.549300, 2023 | 1 | 2023 |
Chronic Cochlear Implantation with and without Electric Stimulation in a Mouse Model Induces Robust Cochlear Influx of CX3CR1+/GFP Macrophages AD Claussen, RV Quevedo, T Higgins, B Mostaert, MT Rahman, J Kirk, ... bioRxiv, 2021.10. 31.466540, 2021 | 1 | 2021 |
Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro Z Safikhani, P Smirnov, KL Thu, J Silvester, N El-Hachem, R Quevedo, ... Nature communications 9 (1), 166, 2018 | 1 | 2018 |
KSR1 knockout mouse model demonstrates MAPK pathway's key role in cisplatin-and noise-induced hearing loss MA Ingersoll, RD Lutze, RG Kelmann, DF Kresock, JD Marsh, ... Journal of Neuroscience, 2024 | | 2024 |
Dabrafenib alters MDSC differentiation and function by activation of GCN2 MT Ciudad, R Quevedo, S Lamorte, R Jin, N Nzirorera, M Koritzinsky, ... Cancer Research Communications, 2024 | | 2024 |