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Rene Quevedo
Rene Quevedo
University Health Network
Verified email at uhnresearch.ca
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Year
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity
K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ...
Immunity 55 (2), 324-340. e8, 2022
2062022
Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling
SK Loganathan, K Schleicher, A Malik, R Quevedo, E Langille, K Teng, ...
Science 367 (6483), 1264-1269, 2020
1562020
Revisiting inconsistency in large pharmacogenomic studies
Z Safikhani, P Smirnov, M Freeman, N El-Hachem, A She, Q Rene, ...
F1000Research 5, 2016
1152016
Somatic BRCA1/2 Recovery as a Resistance Mechanism After Exceptional Response to Poly (ADP-ribose) Polymerase Inhibition
S Lheureux, JP Bruce, JV Burnier, K Karakasis, PA Shaw, BA Clarke, ...
Journal of clinical oncology 35 (11), 1240-1249, 2017
922017
Activating mutations affecting the Dbl homology domain of SOS2 cause Noonan syndrome
V Cordeddu, JC Yin, C Gunnarsson, C Virtanen, S Drunat, F Lepri, ...
Human mutation 36 (11), 1080-1087, 2015
872015
Landscape of genomic alterations in high-grade serous ovarian cancer from exceptional long-and short-term survivors
SYC Yang, S Lheureux, K Karakasis, JV Burnier, JP Bruce, DL Clouthier, ...
Genome medicine 10, 1-17, 2018
822018
Gene isoforms as expression-based biomarkers predictive of drug response in vitro
Z Safikhani, P Smirnov, KL Thu, J Silvester, N El-Hachem, R Quevedo, ...
Nature communications 8 (1), 1126, 2017
702017
Assessment of pharmacogenomic agreement
Z Safikhani, N El-Hachem, R Quevedo, P Smirnov, A Goldenberg, ...
F1000Research 5, 2016
382016
The transcription factor IRF2 drives interferon-mediated CD8+ T cell exhaustion to restrict anti-tumor immunity
S Lukhele, D Abd Rabbo, M Guo, J Shen, HJ Elsaesser, R Quevedo, ...
Immunity 55 (12), 2369-2385. e10, 2022
372022
Pre-encoded responsiveness to type I interferon in the peripheral immune system defines outcome of PD1 blockade therapy
GM Boukhaled, R Gadalla, HJ Elsaesser, D Abd-Rabbo, R Quevedo, ...
Nature immunology 23 (8), 1273-1283, 2022
232022
Assessment of genetic drift in large pharmacogenomic studies
R Quevedo, P Smirnov, D Tkachuk, C Ho, N El-Hachem, Z Safikhani, ...
Cell systems 11 (4), 393-401. e2, 2020
192020
An integrative DNA sequencing and methylation panel to assess mismatch repair deficiency
LE Oldfield, T Li, A Tone, M Aronson, M Edwards, S Holter, R Quevedo, ...
The Journal of Molecular Diagnostics 23 (2), 242-252, 2021
132021
Centromeric cohesion failure invokes a conserved choreography of chromosomal mis-segregations in pancreatic neuroendocrine tumor
R Quevedo, A Spreafico, J Bruce, A Danesh, S El Ghamrasni, A Giesler, ...
Genome Medicine 12, 1-15, 2020
122020
Heterogeneous alteration of the ERBB3–MYC axis associated with MEK inhibitor resistance in a KRAS-mutated low-grade serous ovarian cancer patient
I Colombo, S Garg, A Danesh, J Bruce, P Shaw, Q Tan, R Quevedo, ...
Molecular Case Studies 5 (6), a004341, 2019
72019
Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer
S El Ghamrasni, R Quevedo, J Hawley, P Mazrooei, Y Hanna, I Cirlan, ...
Molecular Cancer Research 20 (1), 102-113, 2022
32022
EHMT2/G9a-Inhibition Reprograms Cancer-Associated Fibroblasts (CAFs) to a More Differentiated, Less Proliferative and Invasive State
NC Wu, R Quevedo, M Nurse, K Hezaveh, H Liu, F Sun, J Muffat, Y Sun, ...
bioRxiv, 2023.07. 17.549300, 2023
12023
Chronic Cochlear Implantation with and without Electric Stimulation in a Mouse Model Induces Robust Cochlear Influx of CX3CR1+/GFP Macrophages
AD Claussen, RV Quevedo, T Higgins, B Mostaert, MT Rahman, J Kirk, ...
bioRxiv, 2021.10. 31.466540, 2021
12021
Author Correction: Gene isoforms as expression-based biomarkers predictive of drug response in vitro
Z Safikhani, P Smirnov, KL Thu, J Silvester, N El-Hachem, R Quevedo, ...
Nature communications 9 (1), 166, 2018
12018
KSR1 knockout mouse model demonstrates MAPK pathway's key role in cisplatin-and noise-induced hearing loss
MA Ingersoll, RD Lutze, RG Kelmann, DF Kresock, JD Marsh, ...
Journal of Neuroscience, 2024
2024
Dabrafenib alters MDSC differentiation and function by activation of GCN2
MT Ciudad, R Quevedo, S Lamorte, R Jin, N Nzirorera, M Koritzinsky, ...
Cancer Research Communications, 2024
2024
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