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Kalpana Ghoshal
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MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
F Meng, R Henson, H Wehbe–Janek, K Ghoshal, ST Jacob, T Patel
Gastroenterology 133 (2), 647-658, 2007
34962007
MicroRNA-221/222 Confers Tamoxifen Resistance in Breast Cancer by Targeting p27Kip1*♦
TE Miller, K Ghoshal, B Ramaswamy, S Roy, J Datta, CL Shapiro, S Jacob, ...
Journal of biological chemistry 283 (44), 29897-29903, 2008
9332008
Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
S Hsu, B Wang, J Kota, J Yu, S Costinean, H Kutay, L Yu, S Bai, ...
The Journal of clinical investigation 122 (8), 2871-2883, 2012
8262012
Downregulation of miR‐122 in the rodent and human hepatocellular carcinomas
H Kutay, S Bai, J Datta, T Motiwala, I Pogribny, W Frankel, ST Jacob, ...
Journal of cellular biochemistry 99 (3), 671-678, 2006
7962006
MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib
S Bai, MW Nasser, B Wang, SH Hsu, J Datta, H Kutay, A Yadav, G Nuovo, ...
Journal of Biological Chemistry 284 (46), 32015-32027, 2009
6352009
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues.
BDP Eichhorn SW, Guo H, McGeary SE, Rodriguez-Mias RA, Shin C, Baek D, Hsu ...
Molecular Cell 56 (1), 104-115, 2014
5952014
mRNA destabilization is the dominant effect of mammalian microRNAs by the time substantial repression ensues.
BDP Eichhorn SW, Guo H, McGeary SE, Rodriguez-Mias RA, Shin C, Baek D, Hsu ...
Molecular Cell 56 (1), 104-115, 2014
5952014
RETRACTED: Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis
J Datta, H Kutay, MW Nasser, GJ Nuovo, B Wang, S Majumder, CG Liu, ...
Cancer research 68 (13), 5049-5058, 2008
5712008
5-Aza-deoxycytidine induces selective degradation of DNA methyltransferase 1 by a proteasomal pathway that requires the KEN box, bromo-adjacent homology domain, and nuclear …
K Ghoshal, J Datta, S Majumder, S Bai, H Kutay, T Motiwala, ST Jacob
Molecular and cellular biology, 2005
5302005
TGFβ-mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3
B Wang, SH Hsu, S Majumder, H Kutay, W Huang, ST Jacob, K Ghoshal
Oncogene 29 (12), 1787-1797, 2010
4772010
CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma
J Chu, Y Deng, DM Benson, S He, T Hughes, J Zhang, Y Peng, H Mao, ...
Leukemia 28 (4), 917-927, 2014
4642014
Down-regulation of micro-RNA-1 (miR-1) in lung cancer: suppression of tumorigenic property of lung cancer cells and their sensitization to doxorubicin-induced apoptosis by miR-1
MW Nasser, J Datta, G Nuovo, H Kutay, T Motiwala, S Majumder, B Wang, ...
Journal of biological chemistry 283 (48), 33394-33406, 2008
4622008
Role of microRNA‐155 at early stages of hepatocarcinogenesis induced by choline‐deficient and amino acid–defined diet in C57BL/6 mice
B Wang, S Majumder, G Nuovo, H Kutay, S Volinia, T Patel, ...
Hepatology 50 (4), 1152-1161, 2009
3712009
A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation
J Datta, K Ghoshal, WA Denny, SA Gamage, DG Brooke, P Phiasivongsa, ...
Cancer research 69 (10), 4277, 2009
3012009
Stat3‐mediated activation of microRNA‐23a suppresses gluconeogenesis in hepatocellular carcinoma by down‐regulating glucose‐6‐phosphatase and peroxisome proliferator‐activated …
B Wang, SH Hsu, W Frankel, K Ghoshal, ST Jacob
Hepatology 56 (1), 186-197, 2012
2492012
miR-122 is a unique molecule with great potential in diagnosis, prognosis of liver disease, and therapy both as miRNA mimic and antimir
S Thakral, K Ghoshal
Current gene therapy 15 (2), 142-150, 2015
2402015
A folate-and methyl-deficient diet alters the expression of DNA methyltransferases and methyl CpG binding proteins involved in epigenetic gene silencing in livers of F344 rats
K Ghoshal, X Li, J Datta, S Bai, I Pogribny, M Pogribny, Y Huang, D Young, ...
The Journal of nutrition 136 (6), 1522-1527, 2006
2392006
Role of human ribosomal RNA (rRNA) promoter methylation and of methyl-CpG-binding protein MBD2 in the suppression of rRNA gene expression
K Ghoshal, S Majumder, J Datta, T Motiwala, S Bai, SM Sharma, ...
Journal of Biological Chemistry 279 (8), 6783-6793, 2004
2262004
An alternative molecular mechanism of action of 5-fluorouracil, a potent anticancer drug
K Ghoshal, ST Jacob
Biochemical pharmacology 53 (11), 1569-1575, 1997
1981997
DNA methyltransferases as targets for cancer therapy.
K Ghoshal, S Bai
Drugs of Today (Barcelona, Spain: 1998) 43 (6), 395-422, 2007
1922007
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