| Single-cell analysis of human pancreas reveals transcriptional signatures of aging and somatic mutation patterns M Enge, HE Arda, M Mignardi, J Beausang, R Bottino, SK Kim, SR Quake Cell 171 (2), 321-330. e14, 2017 | 493 | 2017 |
| Diet-induced developmental acceleration independent of TOR and insulin in C. elegans LT MacNeil, E Watson, HE Arda, LJ Zhu, AJM Walhout Cell 153 (1), 240-252, 2013 | 299 | 2013 |
| Age-dependent pancreatic gene regulation reveals mechanisms governing human β cell function HE Arda, L Li, J Tsai, EA Torre, Y Rosli, H Peiris, RC Spitale, C Dai, X Gu, ... Cell metabolism 23 (5), 909-920, 2016 | 234 | 2016 |
| Gene regulatory networks governing pancreas development HE Arda, CM Benitez, SK Kim Developmental cell 25 (1), 5-13, 2013 | 193 | 2013 |
| Integration of metabolic and gene regulatory networks modulates the C. elegans dietary response E Watson, LT MacNeil, HE Arda, LJ Zhu, AJM Walhout Cell 153 (1), 253-266, 2013 | 137 | 2013 |
| Functional modularity of nuclear hormone receptors in a Caenorhabditis elegans metabolic gene regulatory network HE Arda, S Taubert, LT MacNeil, CC Conine, B Tsuda, M Van Gilst, ... Molecular systems biology 6 (1), 2010 | 118 | 2010 |
| Gateway-compatible yeast one-hybrid screens B Deplancke, V Vermeirssen, HE Arda, NJ Martinez, AJM Walhout Cold Spring Harbor Protocols 2006 (5), pdb. prot4590, 2006 | 80 | 2006 |
| Aggressive PDACs show hypomethylation of repetitive elements and the execution of an intrinsic IFN program linked to a ductal cell of origin E Espinet, Z Gu, CD Imbusch, NA Giese, M Büscher, M Safavi, ... Cancer discovery 11 (3), 638-659, 2021 | 79 | 2021 |
| Matrix and Steiner-triple-system smart pooling assays for high-performance transcription regulatory network mapping V Vermeirssen, B Deplancke, MI Barrasa, JS Reece-Hoyes, HE Arda, ... Nature methods 4 (8), 659-664, 2007 | 74 | 2007 |
| Transcription factor activity mapping of a tissue-specific in vivo gene regulatory network LT MacNeil, C Pons, HE Arda, GE Giese, CL Myers, AJM Walhout Cell systems 1 (2), 152-162, 2015 | 68 | 2015 |
| An Integrated Cell Purification and Genomics Strategy Reveals Multiple Regulators of Pancreas Development CM Benitez, K Qu, T Sugiyama, PT Pauerstein, Y Liu, J Tsai, X Gu, ... PLOS Genetics 10 (10), e1004645, 2014 | 67 | 2014 |
| Gene-centered regulatory networks HE Arda, AJM Walhout Briefings in functional genomics 9 (1), 4-12, 2010 | 63 | 2010 |
| The C. elegans Snail homolog CES-1 can activate gene expression in vivo and share targets with bHLH transcription factors JS Reece-Hoyes, B Deplancke, MI Barrasa, J Hatzold, RB Smit, HE Arda, ... Nucleic acids research 37 (11), 3689-3698, 2009 | 48 | 2009 |
| Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease B Hsueh, VM Burns, P Pauerstein, K Holzem, L Ye, K Engberg, AC Wang, ... Scientific reports 7 (1), 5899, 2017 | 38 | 2017 |
| A chromatin basis for cell lineage and disease risk in the human pancreas HE Arda, J Tsai, YR Rosli, P Giresi, R Bottino, WJ Greenleaf, HY Chang, ... Cell systems 7 (3), 310-322. e4, 2018 | 37 | 2018 |
| A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis PT Pauerstein, K Tellez, KB Willmarth, KM Park, B Hsueh, H Efsun Arda, ... Development 144 (20), 3744-3754, 2017 | 24 | 2017 |
| Single-cell transcriptome and accessible chromatin dynamics during endocrine pancreas development E Duvall, CM Benitez, K Tellez, M Enge, PT Pauerstein, L Li, S Baek, ... Proceedings of the National Academy of Sciences 119 (26), e2201267119, 2022 | 20 | 2022 |
| A transcriptionally distinct subpopulation of healthy acinar cells exhibit features of pancreatic progenitors and PDAC V Gopalan, A Singh, F Rashidi Mehrabadi, L Wang, E Ruppin, HE Arda, ... Cancer research 81 (15), 3958-3970, 2021 | 11 | 2021 |
| The methyltransferases METTL7A and METTL7B confer resistance to thiol-based histone deacetylase inhibitors RW Robey, CM Fitzsimmons, WM Guiblet, WJE Frye, ... Molecular Cancer Therapeutics 23 (4), 464-477, 2024 | 3 | 2024 |
| Single cell transcriptome analysis of human pancreas reveals transcriptional signatures of aging and somatic mutation patterns M Enge, HE Arda, M Mignardi, J Beausang, R Bottino, SK Kim, SR Quake bioRxiv, 108043, 2017 | 1 | 2017 |
Albertha J M WalhoutProfessor and Chair, Department of Systems Biology, UMass Medical SchoolVerified email at umassmed.edu
