Drug absorption interactions between oral targeted anticancer agents and PPIs: is pH‐dependent solubility the Achilles heel of targeted therapy? NR Budha, A Frymoyer, GS Smelick, JY Jin, MR Yago, MJ Dresser, ... Clinical Pharmacology & Therapeutics 92 (2), 203-213, 2012 | 348 | 2012 |
4-methylumbelliferone treatment and hyaluronan inhibition as a therapeutic strategy in inflammation, autoimmunity, and cancer N Nagy, HF Kuipers, AR Frymoyer, HD Ishak, JB Bollyky, TN Wight, ... Frontiers in immunology 6, 123, 2015 | 299 | 2015 |
Prevalence of acid-reducing agents (ARA) in cancer populations and ARA drug–drug interaction potential for molecular targeted agents in clinical development GS Smelick, TP Heffron, L Chu, B Dean, DA West, SL DuVall, BL Lum, ... Molecular pharmaceutics 10 (11), 4055-4062, 2013 | 177 | 2013 |
Current recommended dosing of vancomycin for children with invasive methicillin-resistant Staphylococcus aureus infections is inadequate A Frymoyer, AL Hersh, LZ Benet, BJ Guglielmo The Pediatric infectious disease journal 28 (5), 398-402, 2009 | 174 | 2009 |
Association between vancomycin trough concentration and area under the concentration-time curve in neonates A Frymoyer, AL Hersh, MH El-Komy, S Gaskari, F Su, DR Drover, ... Antimicrobial agents and chemotherapy 58 (11), 6454-6461, 2014 | 143 | 2014 |
Desired vancomycin trough serum concentration for treating invasive methicillin-resistant Staphylococcal infections A Frymoyer, BJ Guglielmo, AL Hersh The Pediatric infectious disease journal 32 (10), 1077-1079, 2013 | 142 | 2013 |
Model‐informed precision dosing at the bedside: scientific challenges and opportunities RJ Keizer, R Ter Heine, A Frymoyer, LJ Lesko, R Mangat, S Goswami CPT: pharmacometrics & systems pharmacology 7 (12), 785-787, 2018 | 102 | 2018 |
Clinical monitoring of well-appearing infants born to mothers with chorioamnionitis NS Joshi, A Gupta, JM Allan, RS Cohen, JL Aby, B Weldon, JL Kim, ... Pediatrics 141 (4), 2018 | 69 | 2018 |
Gentamicin pharmacokinetics and dosing in neonates with hypoxic ischemic encephalopathy receiving hypothermia A Frymoyer, L Meng, SL Bonifacio, D Verotta, BJ Guglielmo Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 33 (7 …, 2013 | 64 | 2013 |
Gastric reacidification with betaine HCl in healthy volunteers with rabeprazole-induced hypochlorhydria MR Yago, AR Frymoyer, GS Smelick, LA Frassetto, NR Budha, ... Molecular pharmaceutics 10 (11), 4032-4037, 2013 | 58 | 2013 |
Predictive performance of a vancomycin population pharmacokinetic model in neonates C Stockmann, AL Hersh, JK Roberts, J Bhongsatiern, EK Korgenski, ... Infectious Diseases and Therapy 4, 187-198, 2015 | 57 | 2015 |
Prediction of vancomycin pharmacodynamics in children with invasive methicillin-resistant Staphylococcus aureus infections: a Monte Carlo simulation A Frymoyer, AL Hersh, Z Coralic, LZ Benet, BJ Guglielmo Clinical therapeutics 32 (3), 534-542, 2010 | 54 | 2010 |
Delayed distribution of active vasodilation and altered vascular conductance in aged skin JM Pierzga, A Frymoyer, WL Kenney Journal of Applied Physiology 94 (3), 1045-1053, 2003 | 53 | 2003 |
Decreased morphine clearance in neonates with hypoxic ischemic encephalopathy receiving hypothermia A Frymoyer, SL Bonifacio, DR Drover, F Su, CJ Wustoff, KP Van Meurs The Journal of Clinical Pharmacology 57 (1), 64-76, 2017 | 52 | 2017 |
Nevirapine pharmacokinetics and risk of rash and hepatitis among HIV-infected sub-Saharan African women BJ Dong, Y Zheng, MD Hughes, A Frymoyer, D Verotta, P Lizak, F Sawe, ... Aids 26 (7), 833-841, 2012 | 52 | 2012 |
Impact of a hospitalwide increase in empiric pediatric vancomycin dosing on initial trough concentrations A Frymoyer, BJ Guglielmo, SD Wilson, SB Scarpace, LZ Benet, AL Hersh Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy 31 (9 …, 2011 | 52 | 2011 |
The use of betaine HCl to enhance dasatinib absorption in healthy volunteers with rabeprazole-induced hypochlorhydria MR Yago, A Frymoyer, LZ Benet, GS Smelick, LA Frassetto, X Ding, ... The AAPS journal 16, 1358-1365, 2014 | 51 | 2014 |
Model-informed precision dosing of vancomycin in hospitalized children: implementation and adoption at an academic children’s hospital A Frymoyer, HT Schwenk, Y Zorn, L Bio, JD Moss, B Chasmawala, ... Frontiers in Pharmacology 11, 551, 2020 | 48 | 2020 |
The pharmacokinetics and dosing of oral 4-methylumbelliferone for inhibition of hyaluronan synthesis in mice HF Kuipers, N Nagy, SM Ruppert, VG Sunkari, PL Marshall, JA Gebe, ... Clinical & Experimental Immunology 185 (3), 372-381, 2016 | 48 | 2016 |
Management of chorioamnionitis-exposed infants in the newborn nursery using a clinical examination–based approach NS Joshi, A Gupta, JM Allan, RS Cohen, JL Aby, JL Kim, WE Benitz, ... Hospital pediatrics 9 (4), 227-233, 2019 | 45 | 2019 |