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Doug Grosenbach
Doug Grosenbach
Senior Director Virus Research, SIGA Technologies, Inc.
Verified email at siga.com
Title
Cited by
Cited by
Year
Oral tecovirimat for the treatment of smallpox
DW Grosenbach, K Honeychurch, EA Rose, J Chinsangaram, A Frimm, ...
New England Journal of Medicine 379 (1), 44-53, 2018
3692018
Phase I study of sequential vaccinations with fowlpox-CEA (6D)-TRICOM alone and sequentially with vaccinia-CEA (6D)-TRICOM, with and without granulocyte-macrophage colony …
JL Marshall, JL Gulley, PM Arlen, PK Beetham, KY Tsang, R Slack, ...
Journal of Clinical Oncology 23 (4), 720-731, 2005
3532005
A randomized phase II study of concurrent docetaxel plus vaccine versus vaccine alone in metastatic androgen-independent prostate cancer.
PM Arlen, JL Gulley, C Parker, L Skarupa, M Pazdur, D Panicali, ...
Clinical cancer research: an official journal of the American Association …, 2006
3432006
IL-2 immunotoxin denileukin diftitox reduces regulatory T cells and enhances vaccine-mediated T-cell immunity
MT Litzinger, R Fernando, TJ Curiel, DW Grosenbach, J Schlom, ...
Blood, The Journal of the American Society of Hematology 110 (9), 3192-3201, 2007
2182007
Synergy of vaccine strategies to amplify antigen-specific immune responses and antitumor effects
DW Grosenbach, JC Barrientos, J Schlom, JW Hodge
Cancer research 61 (11), 4497-4505, 2001
1852001
A novel inhibitor of dengue virus replication that targets the capsid protein
CM Byrd, D Dai, DW Grosenbach, A Berhanu, KF Jones, KB Cardwell, ...
Antimicrobial agents and chemotherapy 57 (1), 15-25, 2013
1562013
An overview of tecovirimat for smallpox treatment and expanded anti-orthopoxvirus applications
AT Russo, DW Grosenbach, J Chinsangaram, KM Honeychurch, PG Long, ...
Expert review of anti-infective therapy 19 (3), 331-344, 2021
1502021
Chlamydia psittaci IncA is phosphorylated by the host cell and is exposed on the cytoplasmic face of the developing inclusion
DD Rockey, D Grosenbach, DE Hruby, MG Peacock, RA Heinzen, ...
Molecular microbiology 24 (1), 217-228, 1997
1481997
Vaccine therapy of established tumors in the absence of autoimmunity
JW Hodge, DW Grosenbach, WM Aarts, DJ Poole, J Schlom
Clinical cancer research 9 (5), 1837-1849, 2003
1392003
Clinical safety of a viral vector based prostate cancer vaccine strategy
PM Arlen, L Skarupa, M Pazdur, M Seetharam, KY Tsang, ...
The Journal of urology 178 (4), 1515-1520, 2007
1362007
Antiandrogen, vaccine and combination therapy in patients with nonmetastatic hormone refractory prostate cancer
PM Arlen, JL Gulley, N Todd, R Lieberman, SM Steinberg, S Morin, ...
The Journal of urology 174 (2), 539-546, 2005
1282005
Enhanced activation of T cells by dendritic cells engineered to hyperexpress a triad of costimulatory molecules
JW Hodge, AN Rad, DW Grosenbach, H Sabzevari, AG Yafal, L Gritz, ...
Journal of the National Cancer Institute 92 (15), 1228-1239, 2000
1122000
Novel benzoxazole inhibitor of dengue virus replication that targets the NS3 helicase
CM Byrd, DW Grosenbach, A Berhanu, D Dai, KF Jones, KB Cardwell, ...
Antimicrobial agents and chemotherapy 57 (4), 1902-1912, 2013
1082013
Development of the small-molecule antiviral ST-246® as a smallpox therapeutic
DW Grosenbach, R Jordan, DE Hruby
Future Virology 6 (5), 653-671, 2011
1062011
Efficacy of tecovirimat (ST-246) in nonhuman primates infected with variola virus (Smallpox)
EM Mucker, AJ Goff, JD Shamblin, DW Grosenbach, IK Damon, JM Mehal, ...
Antimicrobial agents and chemotherapy 57 (12), 6246-6253, 2013
1022013
Vaccination of BALB/c Mice with Escherichia coli-Expressed Vaccinia Virus Proteins A27L, B5R, and D8L Protects Mice from Lethal Vaccinia Virus Challenge
A Berhanu, RL Wilson, DL Kirkwood-Watts, DS King, TK Warren, SA Lund, ...
Journal of virology 82 (7), 3517-3529, 2008
982008
Treatment with the smallpox antiviral tecovirimat (ST-246) alone or in combination with ACAM2000 vaccination is effective as a postsymptomatic therapy for monkeypox virus infection
A Berhanu, JT Prigge, PM Silvera, KM Honeychurch, DE Hruby, ...
Antimicrobial agents and chemotherapy 59 (7), 4296-4300, 2015
972015
Co-administration of tecovirimat and ACAM2000™ in non-human primates: Effect of tecovirimat treatment on ACAM2000 immunogenicity and efficacy versus lethal monkeypox virus …
AT Russo, A Berhanu, CB Bigger, J Prigge, PM Silvera, DW Grosenbach, ...
Vaccine 38 (3), 644-654, 2020
892020
Palmitylation of the vaccinia virus 37-kDa major envelope antigen: identification of a conserved acceptor motif and biological relevance
DW Grosenbach, DO Ulaeto, DE Hruby
Journal of Biological Chemistry 272 (3), 1956-1964, 1997
851997
ST-246 is a key antiviral to inhibit the viral F13L phospholipase, one of the essential proteins for orthopoxvirus wrapping
S Duraffour, MM Lorenzo, G Zöller, D Topalis, D Grosenbach, DE Hruby, ...
Journal of Antimicrobial Chemotherapy 70 (5), 1367-1380, 2015
822015
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