Downstream processing of monoclonal antibodies—application of platform approaches AA Shukla, B Hubbard, T Tressel, S Guhan, D Low Journal of Chromatography B 848 (1), 28-39, 2007 | 1022 | 2007 |
Recent advances in large-scale production of monoclonal antibodies and related proteins AA Shukla, J Thömmes Trends in biotechnology 28 (5), 253-261, 2010 | 654 | 2010 |
Timing of surgery following SARS‐CoV‐2 infection: an international prospective cohort study H Gacaferi, GS Collaborative, COVIDSurg Collaborative Anaesthesia 76 (6), 2021 | 540* | 2021 |
Comparison of commonly used clinical indicators of hypovolaemia with gastrointestinal tonometry C Hamilton-Davies, MG Mythen, JB Salmon, D Jacobson, A Shukla, ... Intensive care medicine 23, 276-281, 1997 | 385 | 1997 |
Single-use disposable technologies for biopharmaceutical manufacturing AA Shukla, U Gottschalk Trends in biotechnology 31 (3), 147-154, 2013 | 310 | 2013 |
Evolving trends in mAb production processes AA Shukla, LS Wolfe, SS Mostafa, C Norman Bioengineering & Translational Medicine 2 (1), 58-69, 2017 | 233 | 2017 |
Host cell protein clearance during protein A chromatography: development of an improved column wash step AA Shukla, P Hinckley Biotechnology progress 24 (5), 1115-1121, 2008 | 222 | 2008 |
Exploitation of the adsorptive properties of depth filters for host cell protein removal during monoclonal antibody purification Y Yigzaw, R Piper, M Tran, AA Shukla Biotechnology progress 22 (1), 288-296, 2006 | 216 | 2006 |
Protein aggregation kinetics during Protein A chromatography: Case study for an Fc fusion protein AA Shukla, P Gupta, X Han Journal of chromatography A 1171 (1-2), 22-28, 2007 | 140 | 2007 |
Defining process design space for monoclonal antibody cell culture SF Abu‐Absi, LY Yang, P Thompson, C Jiang, S Kandula, B Schilling, ... Biotechnology and bioengineering 106 (6), 894-905, 2010 | 129 | 2010 |
High‐throughput miniaturized bioreactors for cell culture process development: Reproducibility, scalability, and control S Rameez, SS Mostafa, C Miller, AA Shukla Biotechnology progress 30 (3), 718-727, 2014 | 122 | 2014 |
Process scale bioseparations for the biopharmaceutical industry AA Shukla, MR Etzel, S Gadam CRC press, 2006 | 122 | 2006 |
A mechanistic study of Protein A chromatography resin lifetime C Jiang, J Liu, M Rubacha, AA Shukla Journal of Chromatography A 1216 (31), 5849-5855, 2009 | 115 | 2009 |
The need for innovation in biomanufacturing U Gottschalk, K Brorson, AA Shukla Nature biotechnology 30 (6), 489-492, 2012 | 102 | 2012 |
SARS-CoV-2 infection and venous thromboembolism after surgery: an international prospective cohort study. C COVIDSurg, C GlobalSurg Anaesthesia 77 (1), 28-39, 2022 | 101 | 2022 |
Demonstration of robust host cell protein clearance in biopharmaceutical downstream processes AA Shukla, C Jiang, J Ma, M Rubacha, L Flansburg, SS Lee Biotechnology progress 24 (3), 615-622, 2008 | 97 | 2008 |
Multicentre prospective cohort study of body mass index and postoperative complications following gastrointestinal surgery TM Drake, D Nepogodiev, SJ Chapman, JC Glasbey, C Khatri, CY Kong, ... British Journal of Surgery 103 (9), 1157-1172, 2016 | 83 | 2016 |
Defining process design space for a hydrophobic interaction chromatography (HIC) purification step: application of quality by design (QbD) principles C Jiang, L Flansburg, S Ghose, P Jorjorian, AA Shukla Biotechnology and bioengineering 107 (6), 985-997, 2010 | 82 | 2010 |
Multimodal chromatography: characterization of protein binding and selectivity enhancement through mobile phase modulators LS Wolfe, CP Barringer, SS Mostafa, AA Shukla Journal of Chromatography A 1340, 151-156, 2014 | 62 | 2014 |
Synthesis and characterization of high-affinity, low molecular weight displacers for cation-exchange chromatography AA Shukla, SS Bae, JA Moore, KA Barnthouse, SM Cramer Industrial & engineering chemistry research 37 (10), 4090-4098, 1998 | 61 | 1998 |