James Carothers
James Carothers
Verified email at uw.edu - Homepage
Cited by
Cited by
Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids
F Zhang, JM Carothers, JD Keasling
Nature biotechnology 30 (4), 354-359, 2012
ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway
E Kopp, R Medzhitov, J Carothers, C Xiao, I Douglas, CA Janeway, ...
Genes & development 13 (16), 2059-2071, 1999
Informational complexity and functional activity of RNA structures
JM Carothers, SC Oestreich, JH Davis, JW Szostak
Journal of the American Chemical Society 126 (16), 5130-5137, 2004
Model-driven engineering of RNA devices to quantitatively program gene expression
JM Carothers, JA Goler, D Juminaga, JD Keasling
Science 334 (6063), 1716-1719, 2011
Measurement and modeling of intrinsic transcription terminators
G Cambray, JC Guimaraes, VK Mutalik, C Lam, QA Mai, T Thimmaiah, ...
Nucleic acids research 41 (9), 5139-5148, 2013
Functional information and the emergence of biocomplexity
RM Hazen, PL Griffin, JM Carothers, JW Szostak
Proceedings of the National Academy of Sciences 104 (suppl 1), 8574-8581, 2007
Aptamers selected for higher-affinity binding are not more specific for the target ligand
JM Carothers, SC Oestreich, JW Szostak
Journal of the American Chemical Society 128 (24), 7929-7937, 2006
Chemical synthesis using synthetic biology
JM Carothers, JA Goler, JD Keasling
Current opinion in biotechnology 20 (4), 498-503, 2009
Digital logic circuits in yeast with CRISPR-dCas9 NOR gates
MW Gander, JD Vrana, WE Voje, JM Carothers, E Klavins
Nature communications 8 (1), 1-11, 2017
Selecting RNA aptamers for synthetic biology: investigating magnesium dependence and predicting binding affinity
JM Carothers, JA Goler, Y Kapoor, L Lara, JD Keasling
Nucleic acids research 38 (8), 2736-2747, 2010
Synthetic CRISPR-Cas gene activators for transcriptional reprogramming in bacteria
C Dong, J Fontana, A Patel, JM Carothers, JG Zalatan
Nature communications 9 (1), 1-11, 2018
Solution structure of an informationally complex high-affinity RNA aptamer to GTP
JM Carothers, JH Davis, JJ Chou, JW Szostak
Rna 12 (4), 567-579, 2006
Data science: Accelerating innovation and discovery in chemical engineering
DAC Beck, JM Carothers, VR Subramanian, J Pfaendtner
AIChE Journal 62 (5), 1402-1416, 2016
Designing RNA-based genetic control systems for efficient production from engineered metabolic pathways
JT Stevens, JM Carothers
ACS synthetic biology 4 (2), 107-115, 2015
Regulated Expression of sgRNAs Tunes CRISPRi in E. coli
J Fontana, C Dong, JY Ham, JG Zalatan, JM Carothers
Biotechnology journal 13 (9), 1800069, 2018
Effective CRISPRa-mediated control of gene expression in bacteria must overcome strict target site requirements
J Fontana, C Dong, C Kiattisewee, VP Chavali, BI Tickman, JM Carothers, ...
Nature communications 11 (1), 1-11, 2020
Design-driven, multi-use research agendas to enable applied synthetic biology for global health
JM Carothers
Systems and synthetic biology 7 (3), 79-86, 2013
In vitro selection of RNA aptamers against a composite small molecule-protein surface
KA Plummer, JM Carothers, M Yoshimura, JW Szostak, GL Verdine
Nucleic acids research 33 (17), 5602-5610, 2005
In vitro selection of functional oligonucleotides and the origins of biochemical activity
JM Carothers, JW Szostak
The Aptamer Handbook, Functional Oligonuleotides and Their Applications, Ed …, 2006
Dual-selection for evolution of in vivo functional aptazymes as riboswitch parts
JA Goler, JM Carothers, JD Keasling
Artificial Riboswitches, 221-235, 2014
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