Shuobing Chen

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Citations	980	676
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Alvin LuTango Therapeutics LLC, Harvard UniversityVerified email at alumni.harvard.edu
Hao WuAsa and Patricia Springer Professor, Boston Children's Hospital and Harvard Medical SchoolVerified email at crystal.harvard.edu
Marc KirschnerProfessor of Systems Biology, Harvard Medical SchoolVerified email at hms.harvard.edu
Haoqian M. ZhangBluepha Co. Ltd.Verified email at bluepha.com
Liman ZhangOregon Health and Science UniversityVerified email at ohsu.edu
Handuo ShiStanford UniversityVerified email at stanford.edu
Jingchen FengMachine Learning Engineer, SnapVerified email at snapchat.com
Yang GuangZhengzhou UniversityVerified email at zzu.edu.cn
Ying LuProfessor of Biostatistics, Department of Biomedical Data Science and Radiology (Courtesy), StanfordVerified email at stanford.edu

Shuobing Chen

Department of Biochemistry and Molecular Biophysics, Columbia University Medical Center

Verified email at cumc.columbia.edu

structure biology cryo-EM synthetic biology system biology


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Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization L Zhang, S Chen, J Ruan, J Wu, AB Tong, Q Yin, Y Li, L David, A Lu, ... Science 350 (6259), 404-409, 2015	406	2015
Structural basis for dynamic regulation of the human 26S proteasome S Chen, J Wu, Y Lu, YB Ma, BH Lee, Z Yu, Q Ouyang, DJ Finley, ... Proceedings of the National Academy of Sciences 113 (46), 12991-12996, 2016	166	2016
Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism A Lu, Y Li, FI Schmidt, Q Yin, S Chen, TM Fu, AB Tong, HL Ploegh, Y Mao, ... Nature structural & molecular biology 23 (5), 416-425, 2016	157	2016
Design, construction, and characterization of a set of biosensors for aromatic compounds H Xue, H Shi, Z Yu, S He, S Liu, Y Hou, X Pan, H Wang, P Zheng, C Cui, ... ACS synthetic biology 3 (12), 1011-1014, 2014	51	2014
Massively parallel unsupervised single-particle cryo-EM data clustering via statistical manifold learning J Wu, YB Ma, C Congdon, B Brett, S Chen, Y Xu, Q Ouyang, Y Mao PLoS One 12 (8), e0182130, 2017	49*	2017
Folding DNA into a lipid‐conjugated nanobarrel for controlled reconstitution of membrane Proteins Y Dong, S Chen, S Zhang, J Sodroski, Z Yang, D Liu, Y Mao Angewandte Chemie 130 (8), 2094-2098, 2018	42	2018
Conformational landscape of the p28-bound human proteasome regulatory particle Y Lu, J Wu, Y Dong, S Chen, S Sun, YB Ma, Q Ouyang, D Finley, ... Molecular cell 67 (2), 322-333. e6, 2017	42	2017
Automated design of genetic toggle switches with predetermined bistability S Chen, H Zhang, H Shi, W Ji, J Feng, Y Gong, Z Yang, Q Ouyang ACS synthetic Biology 1 (7), 284-290, 2012	36	2012
Asymmetric structures and conformational plasticity of the uncleaved full-length human immunodeficiency virus envelope glycoprotein trimer S Zhang, K Wang, WL Wang, HT Nguyen, S Chen, M Lu, EP Go, H Ding, ... Journal of virology 95 (24), 10.1128/jvi. 00529-21, 2021	16	2021
Measurements of gene expression at steady state improve the predictability of part assembly HM Zhang, S Chen, H Shi, W Ji, Y Zong, Q Ouyang, C Lou ACS Synthetic Biology 5 (3), 269-273, 2016	15	2016

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