Michael Hayden
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Mutations in ABC1 in Tangier disease and familial high-density lipoprotein deficiency
A Brooks-Wilson, M Marcil, SM Clee, LH Zhang, K Roomp, M van Dam, ...
Nature genetics 22 (4), 336-345, 1999
Unified Huntington's disease rating scale: reliability and consistency
K Kieburtz, JB Penney, P Como, N Ranen, A Feigin, D Abwender, ...
Movement disorders 11 (2), 136-142, 1996
Loss of huntingtin-mediated BDNF gene transcription in Huntington's disease
C Zuccato, A Ciammola, D Rigamonti, BR Leavitt, D Goffredo, L Conti, ...
Science 293 (5529), 493-498, 2001
Huntington disease
GP Bates, R Dorsey, JF Gusella, MR Hayden, C Kay, BR Leavitt, M Nance, ...
Nature reviews Disease primers 1 (1), 1-21, 2015
The relationship between trinucleotide (CAG) repeat length and clinical features of Huntington's disease
SE Andrew, Y Paul Goldberg, B Kremer, H Telenius, J Theilmann, ...
Nature genetics 4 (4), 398-403, 1993
Mutations in HFE2 cause iron overload in chromosome 1q–linked juvenile hemochromatosis
G Papanikolaou, ME Samuels, EH Ludwig, MLE MacDonald, ...
Nature genetics 36 (1), 77-82, 2004
Early mitochondrial calcium defects in Huntington's disease are a direct effect of polyglutamines
AV Panov, CA Gutekunst, BR Leavitt, MR Hayden, JR Burke, ...
Nature neuroscience 5 (8), 731-736, 2002
Huntingtin interacts with REST/NRSF to modulate the transcription of NRSE-controlled neuronal genes
C Zuccato, M Tartari, A Crotti, D Goffredo, M Valenza, L Conti, ...
Nature genetics 35 (1), 76-83, 2003
Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes
J Nasir, SB Floresco, JR O'Kusky, VM Diewert, JM Richman, J Zeisler, ...
Cell 81 (5), 811-823, 1995
A YAC mouse model for Huntington’s disease with full-length mutant huntingtin, cytoplasmic toxicity, and selective striatal neurodegeneration
JG Hodgson, N Agopyan, CA Gutekunst, BR Leavitt, F LePiane, DJ Smith, ...
Neuron 23 (1), 181-192, 1999
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
EJ Slow, J van Raamsdonk, D Rogers, SH Coleman, RK Graham, Y Deng, ...
Human molecular genetics 12 (13), 1555-1567, 2003
Detection of Huntington’s disease decades before diagnosis: the Predict-HD study
JS Paulsen, DR Langbehn, JC Stout, E Aylward, CA Ross, M Nance, ...
Journal of Neurology, Neurosurgery & Psychiatry 79 (8), 874-880, 2008
A new model for prediction of the age of onset and penetrance for Huntington's disease based on CAG length
DR Langbehn, RR Brinkman, D Falush, JS Paulsen, MR Hayden, ...
Clinical genetics 65 (4), 267-277, 2004
A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2
S Hadano, CK Hand, H Osuga, Y Yanagisawa, A Otomo, RS Devon, ...
Nature genetics 29 (2), 166-173, 2001
Cleavage of huntingtin by apopain, a proapoptotic cysteine protease, is modulated by the polyglutamine tract
YP Goldberg, DW Nicholson, DM Rasper, MA Kalchman, HB Koide, ...
Nature genetics 13 (4), 442-449, 1996
Cleavage at the caspase-6 site is required for neuronal dysfunction and degeneration due to mutant huntingtin
RK Graham, Y Deng, EJ Slow, B Haigh, N Bissada, G Lu, J Pearson, ...
Cell 125 (6), 1179-1191, 2006
A worldwide study of the Huntington's disease mutation: the sensitivity and specificity of measuring CAG repeats
B Kremer, P Goldberg, SE Andrew, J Theilmann, H Telenius, J Zeisler, ...
New England Journal of Medicine 330 (20), 1401-1406, 1994
Increased sensitivity to N-methyl-D-aspartate receptor-mediated excitotoxicity in a mouse model of Huntington's disease
MM Zeron, O Hansson, N Chen, CL Wellington, BR Leavitt, P Brundin, ...
Neuron 33 (6), 849-860, 2002
Caspase cleavage of gene products associated with triplet expansion disorders generates truncated fragments containing the polyglutamine tract
CL Wellington, LM Ellerby, AS Hackam, RL Margolis, MA Trifiro, ...
Journal of Biological Chemistry 273 (15), 9158-9167, 1998
A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease
M Björkqvist, EJ Wild, J Thiele, A Silvestroni, R Andre, N Lahiri, ...
The Journal of experimental medicine 205 (8), 1869-1877, 2008
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