Nathanael Gray

Cited by

	All	Since 2018
Citations	81840	46295
h-index	137	106
i10-index	516	460

9000

4500

2250

6750

200020012002200320042005200620072008200920102011201220132014201520162017201820192020202120222023244 298 373 471 508 550 604 659 707 1023 1608 2290 2970 3585 3880 4588 4931 5378 5845 6425 8006 8965 8972 7998

Public access

View all

382 articles

14 articles

available

not available

Based on funding mandates

Co-authors

Richard YoungProfessor of Biology, MITVerified email at wi.mit.edu
Ken WestoverAssociate Professor of Biochemistry and Radiation Oncology, UT SouthwesternVerified email at utsouthwestern.edu
Laurent MeijerVerified email at manros-therapeutics.com
Peter K. SorgerHarvard Medical SchoolVerified email at hms.harvard.edu
Stefan KnappUniversity of FrankfurtVerified email at pharmchem.uni-frankfurt.de
Young-Tae ChangPOSTECHVerified email at postech.ac.kr
Zachary Hunter, PhDDana-Farber Cancer Institute - Bing Center for WMVerified email at dfci.harvard.edu
Lyn JonesDana-Farber Cancer InstituteVerified email at dfci.harvard.edu
Mario NiepelRibon TherapeuticsVerified email at ribontx.com
John R. EngenJames L. Waters Chair & Distinguished Professor of Chemistry, Northeastern UniversityVerified email at neu.edu
Ultan McDermottFaculty, Wellcome Trust Sanger InstituteVerified email at sanger.ac.uk
Elizabeth A. WinzelerProfessor, University of California San Diego, School of MedicineVerified email at ucsd.edu
Badry BursulayaGNFVerified email at gnf.org
Daniel LimMIT Koch InstituteVerified email at mit.edu
Craig MermelPresident and Chief Product Officer, Precision NeuroscienceVerified email at precisionneuro.io
Simon ArthurUniversity of DundeeVerified email at dundee.ac.uk
Roxana IacobResearch Associate Professor, Northeastern UniversityVerified email at neu.edu
Neal RosenProfessor of Pharmacology, Memorial Sloan-Kettering Cancer CenterVerified email at mskcc.org
Thorold W. TheunissenAssociate Professor of Developmental Biology at Washington University in St. LouisVerified email at wustl.edu
Gad GetzMassachusetts General Hospital and Broad Institute of Harvard and MITVerified email at broadinstitute.org

Nathanael Gray

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Verified email at dfci.harvard.edu

medicinal chemistry cancer research structure-based drug design kinase inhibitors chemical biology


Title Sort by citations Sort by year Sort by title	Cited by Cited by	Year
Targeting cancer with small molecule kinase inhibitors J Zhang, PL Yang, NS Gray Nature reviews cancer 9 (1), 28-39, 2009	3191	2009
Systematic identification of genomic markers of drug sensitivity in cancer cells MJ Garnett, EJ Edelman, SJ Heidorn, CD Greenman, A Dastur, KW Lau, ... Nature 483 (7391), 570-575, 2012	2472	2012
A next generation connectivity map: L1000 platform and the first 1,000,000 profiles A Subramanian, R Narayan, SM Corsello, DD Peck, TE Natoli, X Lu, ... Cell 171 (6), 1437-1452. e17, 2017	2331	2017
An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1 CC Thoreen, SA Kang, JW Chang, Q Liu, J Zhang, Y Gao, LJ Reichling, ... Journal of Biological Chemistry 284 (12), 8023-8032, 2009	1977	2009
A landscape of pharmacogenomic interactions in cancer F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ... Cell 166 (3), 740-754, 2016	1583	2016
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival TR Peterson, M Laplante, CC Thoreen, Y Sancak, SA Kang, WM Kuehl, ... Cell 137 (5), 873-886, 2009	1523	2009
A unifying model for mTORC1-mediated regulation of mRNA translation CC Thoreen, L Chantranupong, HR Keys, T Wang, NS Gray, DM Sabatini Nature 485 (7396), 109-113, 2012	1516	2012
Rational design of inhibitors that bind to inactive kinase conformations Y Liu, NS Gray Nature chemical biology 2 (7), 358-364, 2006	1291	2006
A chemical switch for inhibitor-sensitive alleles of any protein kinase AC Bishop, JA Ubersax, DT Petsch, DP Matheos, NS Gray, J Blethrow, ... nature 407 (6802), 395-401, 2000	1230	2000
EML4-ALK Fusion Gene and Efficacy of an ALK Kinase Inhibitor in Lung Cancer JP Koivunen, C Mermel, K Zejnullahu, C Murphy, E Lifshits, AJ Holmes, ... Clinical cancer research 14 (13), 4275-4283, 2008	1196	2008
The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling PP Hsu, SA Kang, J Rameseder, Y Zhang, KA Ottina, D Lim, TR Peterson, ... science 332 (6035), 1317-1322, 2011	1174	2011
Novel mutant-selective EGFR kinase inhibitors against EGFR T790M W Zhou, D Ercan, L Chen, CH Yun, D Li, M Capelletti, AB Cortot, ... Nature 462 (7276), 1070-1074, 2009	1144	2009
Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors NS Gray, L Wodicka, AMWH Thunnissen, TC Norman, S Kwon, ... Science 281 (5376), 533-538, 1998	1136	1998
Activating mutations in ALK provide a therapeutic target in neuroblastoma RE George, T Sanda, M Hanna, S Fröhling, WL Ii, J Zhang, Y Ahn, ... Nature 455 (7215), 975-978, 2008	982	2008
Systematic identification of culture conditions for induction and maintenance of naive human pluripotency TW Theunissen, BE Powell, H Wang, M Mitalipova, DA Faddah, J Reddy, ... Cell stem cell 15 (4), 471-487, 2014	891	2014
The promise and peril of chemical probes CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ... Nature chemical biology 11 (8), 536-541, 2015	801	2015
YY1 is a structural regulator of enhancer-promoter loops AS Weintraub, CH Li, AV Zamudio, AA Sigova, NM Hannett, DS Day, ... Cell 171 (7), 1573-1588. e28, 2017	793	2017
Kinase inhibitors: the road ahead FM Ferguson, NS Gray Nature reviews Drug discovery 17 (5), 353-377, 2018	783	2018
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor N Kwiatkowski, T Zhang, PB Rahl, BJ Abraham, J Reddy, SB Ficarro, ... Nature 511 (7511), 616-620, 2014	780	2014
MEK1 mutations confer resistance to MEK and B-RAF inhibition CM Emery, KG Vijayendran, MC Zipser, AM Sawyer, L Niu, JJ Kim, ... Proceedings of the National Academy of Sciences 106 (48), 20411-20416, 2009	750	2009

The system can't perform the operation now. Try again later.

Articles 1–20

Citations per year

Duplicate citations

Merged citations

Add co-authorsCo-authors

Follow

Cited by

Co-authors