Raamesh Deshpande
Raamesh Deshpande
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The genetic landscape of a cell
M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ...
science 327 (5964), 425-431, 2010
A global genetic interaction network maps a wiring diagram of cellular function
M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ...
Science 353 (6306), aaf1420, 2016
Systematic analysis of complex genetic interactions
E Kuzmin, B VanderSluis, W Wang, G Tan, R Deshpande, Y Chen, M Usaj, ...
Science 360 (6386), eaao1729, 2018
Forazoline A: marine‐derived polyketide with antifungal in vivo efficacy
TP Wyche, JS Piotrowski, Y Hou, D Braun, R Deshpande, S McIlwain, ...
Angewandte Chemie International Edition 53 (43), 11583-11586, 2014
Plant-derived antifungal agent poacic acid targets β-1, 3-glucan
JS Piotrowski, H Okada, F Lu, SC Li, L Hinchman, A Ranjan, DL Smith, ...
Proceedings of the National Academy of Sciences 112 (12), E1490-E1497, 2015
Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model
HAF Stessman, LB Baughn, A Sarver, T Xia, R Deshpande, A Mansoor, ...
Molecular cancer therapeutics 12 (6), 1140-1150, 2013
Unraveling the biology of a fungal meningitis pathogen using chemical genetics
JCS Brown, J Nelson, B VanderSluis, R Deshpande, A Butts, S Kagan, ...
Cell 159 (5), 1168-1187, 2014
Functional annotation of chemical libraries across diverse biological processes
JS Piotrowski, SC Li, R Deshpande, SW Simpkins, J Nelson, Y Yashiroda, ...
Nature Chemical Biology 13 (9), 982-993, 2017
A comparative genomic approach for identifying synthetic lethal interactions in human cancer
R Deshpande, MK Asiedu, M Klebig, S Sutor, E Kuzmin, J Nelson, ...
Cancer research 73 (20), 6128-6136, 2013
Conserved rules govern genetic interaction degree across species
EN Koch, M Costanzo, J Bellay, R Deshpande, K Chatfield-Reed, G Chua, ...
Genome biology 13, 1-15, 2012
A global genetic interaction network maps a wiring diagram of cellular function. Science 353: aaf1420
M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ...
Padanamides A and B, Highly Modified Linear Tetrapeptides Produced in Culture by a Streptomyces sp. Isolated from a Marine Sediment
DE Williams, DS Dalisay, BO Patrick, T Matainaho, K Andrusiak, ...
Organic letters 13 (15), 3936-3939, 2011
Chemical genomic profiling via barcode sequencing to predict compound mode of action
JS Piotrowski, SW Simpkins, SC Li, R Deshpande, SJ McIlwain, IM Ong, ...
Chemical Biology: Methods and Protocols, 299-318, 2015
Comparison of profile similarity measures for genetic interaction networks
R Deshpande, B VanderSluis, CL Myers
PloS one 8 (7), e68664, 2013
Unbiased screening of marine sponge extracts for anti-inflammatory agents combined with chemical genomics identifies girolline as an inhibitor of protein synthesis
SY Fung, V Sofiyev, J Schneiderman, AF Hirschfeld, RE Victor, K Woods, ...
ACS chemical biology 9 (1), 247-257, 2014
A scalable approach for discovering conserved active subnetworks across species
R Deshpande, S Sharma, CM Verfaillie, WS Hu, CL Myers
PLoS computational biology 6 (12), e1001028, 2010
A general biological simulator: the multiscale object oriented simulation environment, MOOSE
S Ray, R Deshpande, N Dudani, US Bhalla
BMC Neuroscience 9, 1-2, 2008
Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions
SW Simpkins, J Nelson, R Deshpande, SC Li, JS Piotrowski, EH Wilson, ...
PLoS computational biology 14 (10), e1006532, 2018
Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments
SW Simpkins, R Deshpande, J Nelson, SC Li, JS Piotrowski, HN Ward, ...
Nature protocols 14 (2), 415-440, 2019
Efficient strategies for screening large-scale genetic interaction networks
R Deshpande, J Nelson, SW Simpkins, M Costanzo, JS Piotrowski, SC Li, ...
BioRxiv, 159632, 2017
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