Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease MH Voutilainen, S Bäck, E Pörsti, L Toppinen, L Lindgren, P Lindholm, ... Journal of Neuroscience 29 (30), 9651-9659, 2009 | 335 | 2009 |
Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease MH Voutilainen, S Bäck, J Peränen, P Lindholm, A Raasmaja, ... Experimental neurology 228 (1), 99-108, 2011 | 168 | 2011 |
Gene therapy with AAV 2‐CDNF provides functional benefits in a rat model of P arkinson's disease S Bäck, J Peränen, E Galli, P Pulkkila, L Lonka‐Nevalaita, T Tamminen, ... Brain and behavior 3 (2), 75-88, 2013 | 104 | 2013 |
KDEL receptors are differentially regulated to maintain the ER proteome under calcium deficiency KA Trychta, S Bäck, MJ Henderson, BK Harvey Cell reports 25 (7), 1829-1840. e6, 2018 | 102 | 2018 |
Neuron-specific genome modification in the adult rat brain using CRISPR-Cas9 transgenic rats S Bäck, J Necarsulmer, LR Whitaker, LM Coke, P Koivula, EJ Heathward, ... Neuron 102 (1), 105-119. e8, 2019 | 77 | 2019 |
Update of neurotrophic factors in neurobiology of addiction and future directions M Koskela, S Bäck, V Võikar, CT Richie, A Domanskyi, BK Harvey, ... Neurobiology of disease 97, 189-200, 2017 | 74 | 2017 |
High fat diet disrupts endoplasmic reticulum calcium homeostasis in the rat liver ES Wires, KA Trychta, S Bäck, A Sulima, KC Rice, BK Harvey Journal of hepatology 67 (5), 1009-1017, 2017 | 54 | 2017 |
Evidence for an additive neurorestorative effect of simultaneously administered CDNF and GDNF in hemiparkinsonian rats: implications for different mechanism of action MH Voutilainen, F De Lorenzo, P Stepanova, S Bäck, LY Yu, P Lindholm, ... Eneuro 4 (1), 2017 | 53 | 2017 |
Pre-α-pro-GDNF and pre-β-pro-GDNF isoforms are neuroprotective in the 6-hydroxydopamine rat model of Parkinson's disease AM Penttinen, I Parkkinen, MH Voutilainen, M Koskela, S Bäck, A Their, ... Frontiers in neurology 9, 371449, 2018 | 32 | 2018 |
Combination of CDNF and deep brain stimulation decreases neurological deficits in late-stage model Parkinson’s disease A Huotarinen, AM Penttinen, S Bäck, MH Voutilainen, U Julku, ... Neuroscience 374, 250-263, 2018 | 30 | 2018 |
High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA … S Bäck, M Raki, RK Tuominen, A Raasmaja, K Bergström, PT Männistö EJNMMI research 3, 1-10, 2013 | 30 | 2013 |
Surge of peripheral arginine vasopressin in a rat model of birth asphyxia M Summanen, S Bäck, J Voipio, K Kaila Frontiers in Cellular Neuroscience 12, 2, 2018 | 29 | 2018 |
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome MJ Henderson, KA Trychta, SM Yang, S Bäck, A Yasgar, ES Wires, ... Cell reports 35 (4), 2021 | 16 | 2021 |
Mesencephalic astrocyte-derived neurotrophic factor (MANF) elevates stimulus-evoked release of dopamine in freely-moving rats JM Renko, S Bäck, MH Voutilainen, TP Piepponen, I Reenilä, M Saarma, ... Molecular neurobiology 55, 6755-6768, 2018 | 15 | 2018 |
Longitudinal monitoring of Gaussia and Nano luciferase activities to concurrently assess ER calcium homeostasis and ER stress in vivo ES Wires, MJ Henderson, X Yan, S Bäck, KA Trychta, MH Lutrey, ... PLoS One 12 (4), e0175481, 2017 | 14 | 2017 |
Neuronal activation stimulates cytomegalovirus promoter-driven transgene expression S Bäck, A Dossat, I Parkkinen, P Koivula, M Airavaara, CT Richie, ... Molecular Therapy-Methods & Clinical Development 14, 180-188, 2019 | 11 | 2019 |
Extracellular esterase activity as an indicator of endoplasmic reticulum calcium depletion KA Trychta, EJ Heathward, A Sulima, S Bäck, M Farokhnia, CT Richie, ... Biomarkers 23 (8), 756-765, 2018 | 10 | 2018 |
Synthesis and biological evaluation of novel 123I-labeled 4-(4-iodophenyl) butanoyl-l-prolyl-(2S)-pyrrolidines for imaging prolyl oligopeptidase in vivo A Kallinen, B Todorov, R Kallionpää, S Bäck, M Sarparanta, M Raki, ... European Journal of Medicinal Chemistry 79, 436-445, 2014 | 3 | 2014 |
Activation of the CMV promoter: Considerations for viral vector-mediated transgene expression D Howard, S Back, A Dossat, YH Chen, Y Wang, BK Harvey MOLECULAR THERAPY 27 (4), 161-161, 2019 | | 2019 |
Loss of ER resident proteins in response to calcium depletion is counteracted by KDEL receptor upregulation. K Trychta, S Back, M Henderson, BK Harvey MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018 | | 2018 |