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Susanne Bäck
Susanne Bäck
Senior Scientist, R&D Therapy Area CNS, Disease Biology - Neurodegeneration, Orion Pharma, Turku
Verified email at orionpharma.com
Title
Cited by
Cited by
Year
Mesencephalic astrocyte-derived neurotrophic factor is neurorestorative in rat model of Parkinson's disease
MH Voutilainen, S Bäck, E Pörsti, L Toppinen, L Lindgren, P Lindholm, ...
Journal of Neuroscience 29 (30), 9651-9659, 2009
3352009
Chronic infusion of CDNF prevents 6-OHDA-induced deficits in a rat model of Parkinson's disease
MH Voutilainen, S Bäck, J Peränen, P Lindholm, A Raasmaja, ...
Experimental neurology 228 (1), 99-108, 2011
1682011
Gene therapy with AAV 2‐CDNF provides functional benefits in a rat model of P arkinson's disease
S Bäck, J Peränen, E Galli, P Pulkkila, L Lonka‐Nevalaita, T Tamminen, ...
Brain and behavior 3 (2), 75-88, 2013
1042013
KDEL receptors are differentially regulated to maintain the ER proteome under calcium deficiency
KA Trychta, S Bäck, MJ Henderson, BK Harvey
Cell reports 25 (7), 1829-1840. e6, 2018
1022018
Neuron-specific genome modification in the adult rat brain using CRISPR-Cas9 transgenic rats
S Bäck, J Necarsulmer, LR Whitaker, LM Coke, P Koivula, EJ Heathward, ...
Neuron 102 (1), 105-119. e8, 2019
772019
Update of neurotrophic factors in neurobiology of addiction and future directions
M Koskela, S Bäck, V Võikar, CT Richie, A Domanskyi, BK Harvey, ...
Neurobiology of disease 97, 189-200, 2017
742017
High fat diet disrupts endoplasmic reticulum calcium homeostasis in the rat liver
ES Wires, KA Trychta, S Bäck, A Sulima, KC Rice, BK Harvey
Journal of hepatology 67 (5), 1009-1017, 2017
542017
Evidence for an additive neurorestorative effect of simultaneously administered CDNF and GDNF in hemiparkinsonian rats: implications for different mechanism of action
MH Voutilainen, F De Lorenzo, P Stepanova, S Bäck, LY Yu, P Lindholm, ...
Eneuro 4 (1), 2017
532017
Pre-α-pro-GDNF and pre-β-pro-GDNF isoforms are neuroprotective in the 6-hydroxydopamine rat model of Parkinson's disease
AM Penttinen, I Parkkinen, MH Voutilainen, M Koskela, S Bäck, A Their, ...
Frontiers in neurology 9, 371449, 2018
322018
Combination of CDNF and deep brain stimulation decreases neurological deficits in late-stage model Parkinson’s disease
A Huotarinen, AM Penttinen, S Bäck, MH Voutilainen, U Julku, ...
Neuroscience 374, 250-263, 2018
302018
High correlation between in vivo [123I]β-CIT SPECT/CT imaging and post-mortem immunohistochemical findings in the evaluation of lesions induced by 6-OHDA …
S Bäck, M Raki, RK Tuominen, A Raasmaja, K Bergström, PT Männistö
EJNMMI research 3, 1-10, 2013
302013
Surge of peripheral arginine vasopressin in a rat model of birth asphyxia
M Summanen, S Bäck, J Voipio, K Kaila
Frontiers in Cellular Neuroscience 12, 2, 2018
292018
A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome
MJ Henderson, KA Trychta, SM Yang, S Bäck, A Yasgar, ES Wires, ...
Cell reports 35 (4), 2021
162021
Mesencephalic astrocyte-derived neurotrophic factor (MANF) elevates stimulus-evoked release of dopamine in freely-moving rats
JM Renko, S Bäck, MH Voutilainen, TP Piepponen, I Reenilä, M Saarma, ...
Molecular neurobiology 55, 6755-6768, 2018
152018
Longitudinal monitoring of Gaussia and Nano luciferase activities to concurrently assess ER calcium homeostasis and ER stress in vivo
ES Wires, MJ Henderson, X Yan, S Bäck, KA Trychta, MH Lutrey, ...
PLoS One 12 (4), e0175481, 2017
142017
Neuronal activation stimulates cytomegalovirus promoter-driven transgene expression
S Bäck, A Dossat, I Parkkinen, P Koivula, M Airavaara, CT Richie, ...
Molecular Therapy-Methods & Clinical Development 14, 180-188, 2019
112019
Extracellular esterase activity as an indicator of endoplasmic reticulum calcium depletion
KA Trychta, EJ Heathward, A Sulima, S Bäck, M Farokhnia, CT Richie, ...
Biomarkers 23 (8), 756-765, 2018
102018
Synthesis and biological evaluation of novel 123I-labeled 4-(4-iodophenyl) butanoyl-l-prolyl-(2S)-pyrrolidines for imaging prolyl oligopeptidase in vivo
A Kallinen, B Todorov, R Kallionpää, S Bäck, M Sarparanta, M Raki, ...
European Journal of Medicinal Chemistry 79, 436-445, 2014
32014
Activation of the CMV promoter: Considerations for viral vector-mediated transgene expression
D Howard, S Back, A Dossat, YH Chen, Y Wang, BK Harvey
MOLECULAR THERAPY 27 (4), 161-161, 2019
2019
Loss of ER resident proteins in response to calcium depletion is counteracted by KDEL receptor upregulation.
K Trychta, S Back, M Henderson, BK Harvey
MOLECULAR BIOLOGY OF THE CELL 29 (26), 2018
2018
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