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Jim Sun
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Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+–ATPase to inhibit phagosome acidification
D Wong, H Bach, J Sun, Z Hmama, Y Av-Gay
Proceedings of the National Academy of Sciences 108 (48), 19371-19376, 2011
4432011
NAD+ depletion triggers macrophage necroptosis, a cell death pathway exploited by Mycobacterium tuberculosis
D Pajuelo, N Gonzalez-Juarbe, U Tak, J Sun, CJ Orihuela, M Niederweis
Cell reports 24 (2), 429-440, 2018
1562018
Mycobacterial nucleoside diphosphate kinase blocks phagosome maturation in murine RAW 264.7 macrophages
J Sun, X Wang, A Lau, TYA Liao, C Bucci, Z Hmama
PloS one 5 (1), e8769, 2010
1562010
The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD
J Sun, A Siroy, RK Lokareddy, A Speer, KS Doornbos, G Cingolani, ...
Nature structural & molecular biology 22 (9), 672-678, 2015
1322015
An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity
O Danilchanka, J Sun, M Pavlenok, C Maueröder, A Speer, A Siroy, ...
Proceedings of the National Academy of Sciences 111 (18), 6750-6755, 2014
1312014
Mycobacterium bovis BCG disrupts the interaction of Rab7 with RILP contributing to inhibition of phagosome maturation
J Sun, AE Deghmane, H Soualhine, T Hong, C Bucci, A Solodkin, ...
Journal of Leucocyte Biology 82 (6), 1437-1445, 2007
1232007
Mycobacterium tuberculosis Nucleoside Diphosphate Kinase Inactivates Small GTPases Leading to Evasion of Innate Immunity
J Sun, V Singh, A Lau, RW Stokes, A Obregón-Henao, IM Orme, D Wong, ...
PLoS pathogens 9 (7), e1003499, 2013
1072013
8-Hydroxyquinolines are boosting agents of copper-related toxicity in Mycobacterium tuberculosis
S Shah, AG Dalecki, AP Malalasekera, CL Crawford, SM Michalek, ...
Antimicrobial agents and chemotherapy 60 (10), 5765-5776, 2016
742016
Mycobacterium bovis bacillus Calmette-Guerin secreting active cathepsin S stimulates expression of mature MHC class II molecules and antigen presentation in human macrophages
H Soualhine, AE Deghmane, J Sun, K Mak, A Talal, Y Av-Gay, Z Hmama
The Journal of Immunology 179 (8), 5137-5145, 2007
712007
Surface hydrolysis of sphingomyelin by the outer membrane protein Rv0888 supports replication of Mycobacterium tuberculosis in macrophages
A Speer, J Sun, O Danilchanka, V Meikle, JL Rowland, K Walter, BR Buck, ...
Molecular microbiology 97 (5), 881-897, 2015
672015
Mycobacterium avium subsp. paratuberculosis PtpA Is an Endogenous Tyrosine Phosphatase Secreted during Infection
H Bach, J Sun, Z Hmama, Y Av-Gay
Infection and immunity 74 (12), 6540-6546, 2006
602006
Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis
K Schaaf, SR Smith, A Duverger, F Wagner, F Wolschendorf, AO Westfall, ...
Scientific reports 7 (1), 42101, 2017
432017
The phosphatase PPM1A controls monocyte-to-macrophage differentiation
SR Smith, K Schaaf, N Rajabalee, F Wagner, A Duverger, O Kutsch, J Sun
Scientific Reports 8 (1), 902, 2018
362018
Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7
EA Dennis, LE Smythies, R Grabski, M Li, ME Ballestas, M Shimamura, ...
Mucosal immunology 11 (6), 1694-1704, 2018
292018
Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection
J Sun, K Schaaf, A Duverger, F Wolschendorf, A Speer, F Wagner, ...
Oncotarget 7 (13), 15394, 2016
272016
A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis
K Schaaf, V Hayley, A Speer, F Wolschendorf, M Niederweis, O Kutsch, ...
Assay and drug development technologies 14 (6), 345-354, 2016
232016
Detection of activated Rab7 GTPase with an immobilized RILP probe
J Sun, AE Deghmane, C Bucci, Z Hmama
Macrophages and Dendritic Cells: Methods and Protocols, 57-69, 2009
192009
A broad-range of recombination cloning vectors in mycobacteria
J Sun, A Lau, X Wang, TYA Liao, A Zoubeidi, Z Hmama
Plasmid 62 (3), 158-165, 2009
162009
TREM2 promotes immune evasion by mycobacterium tuberculosis in human macrophages
A Dabla, YC Liang, N Rajabalee, C Irwin, CGJ Moonen, JV Willis, ...
MBio 13 (4), e01456-22, 2022
152022
Mycobacterium tuberculosis exploits focal adhesion kinase to induce necrotic cell death and inhibit reactive oxygen species production
A Afriyie-Asante, A Dabla, A Dagenais, S Berton, R Smyth, J Sun
Frontiers in Immunology 12, 742370, 2021
152021
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