| Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+–ATPase to inhibit phagosome acidification D Wong, H Bach, J Sun, Z Hmama, Y Av-Gay Proceedings of the National Academy of Sciences 108 (48), 19371-19376, 2011 | 432 | 2011 |
| Mycobacterial nucleoside diphosphate kinase blocks phagosome maturation in murine RAW 264.7 macrophages J Sun, X Wang, A Lau, TYA Liao, C Bucci, Z Hmama PloS one 5 (1), e8769, 2010 | 150 | 2010 |
| NAD+ depletion triggers macrophage necroptosis, a cell death pathway exploited by Mycobacterium tuberculosis D Pajuelo, N Gonzalez-Juarbe, U Tak, J Sun, CJ Orihuela, M Niederweis Cell reports 24 (2), 429-440, 2018 | 141 | 2018 |
| The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD J Sun, A Siroy, RK Lokareddy, A Speer, KS Doornbos, G Cingolani, ... Nature structural & molecular biology 22 (9), 672-678, 2015 | 128 | 2015 |
| An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity O Danilchanka, J Sun, M Pavlenok, C Maueröder, A Speer, A Siroy, ... Proceedings of the National Academy of Sciences 111 (18), 6750-6755, 2014 | 128 | 2014 |
| Mycobacterium bovis BCG disrupts the interaction of Rab7 with RILP contributing to inhibition of phagosome maturation J Sun, AE Deghmane, H Soualhine, T Hong, C Bucci, A Solodkin, ... Journal of Leucocyte Biology 82 (6), 1437-1445, 2007 | 123 | 2007 |
| Mycobacterium tuberculosis Nucleoside Diphosphate Kinase Inactivates Small GTPases Leading to Evasion of Innate Immunity J Sun, V Singh, A Lau, RW Stokes, A Obregón-Henao, IM Orme, D Wong, ... PLoS pathogens 9 (7), e1003499, 2013 | 103 | 2013 |
| Mycobacterium bovis bacillus Calmette-Guerin secreting active cathepsin S stimulates expression of mature MHC class II molecules and antigen presentation in human macrophages H Soualhine, AE Deghmane, J Sun, K Mak, A Talal, Y Av-Gay, Z Hmama The Journal of Immunology 179 (8), 5137-5145, 2007 | 70 | 2007 |
| 8-Hydroxyquinolines are boosting agents of copper-related toxicity in Mycobacterium tuberculosis S Shah, AG Dalecki, AP Malalasekera, CL Crawford, SM Michalek, ... Antimicrobial agents and chemotherapy 60 (10), 5765-5776, 2016 | 69 | 2016 |
| Surface hydrolysis of sphingomyelin by the outer membrane protein Rv0888 supports replication of Mycobacterium tuberculosis in macrophages A Speer, J Sun, O Danilchanka, V Meikle, JL Rowland, K Walter, BR Buck, ... Molecular microbiology 97 (5), 881-897, 2015 | 65 | 2015 |
| Mycobacterium avium subsp. paratuberculosis PtpA Is an Endogenous Tyrosine Phosphatase Secreted during Infection H Bach, J Sun, Z Hmama, Y Av-Gay Infection and immunity 74 (12), 6540-6546, 2006 | 58 | 2006 |
| Mycobacterium tuberculosis exploits the PPM1A signaling pathway to block host macrophage apoptosis K Schaaf, SR Smith, A Duverger, F Wagner, F Wolschendorf, AO Westfall, ... Scientific reports 7 (1), 42101, 2017 | 42 | 2017 |
| The phosphatase PPM1A controls monocyte-to-macrophage differentiation SR Smith, K Schaaf, N Rajabalee, F Wagner, A Duverger, O Kutsch, J Sun Scientific Reports 8 (1), 902, 2018 | 33 | 2018 |
| Protein phosphatase, Mg2+/Mn2+-dependent 1A controls the innate antiviral and antibacterial response of macrophages during HIV-1 and Mycobacterium tuberculosis infection J Sun, K Schaaf, A Duverger, F Wolschendorf, A Speer, F Wagner, ... Oncotarget 7 (13), 15394, 2016 | 27 | 2016 |
| Cytomegalovirus promotes intestinal macrophage-mediated mucosal inflammation through induction of Smad7 EA Dennis, LE Smythies, R Grabski, M Li, ME Ballestas, M Shimamura, ... Mucosal immunology 11 (6), 1694-1704, 2018 | 24 | 2018 |
| A Macrophage Infection Model to Predict Drug Efficacy Against Mycobacterium Tuberculosis K Schaaf, V Hayley, A Speer, F Wolschendorf, M Niederweis, O Kutsch, ... Assay and drug development technologies 14 (6), 345-354, 2016 | 22 | 2016 |
| Detection of activated Rab7 GTPase with an immobilized RILP probe J Sun, AE Deghmane, C Bucci, Z Hmama Macrophages and Dendritic Cells: Methods and Protocols, 57-69, 2009 | 17 | 2009 |
| A broad-range of recombination cloning vectors in mycobacteria J Sun, A Lau, X Wang, TYA Liao, A Zoubeidi, Z Hmama Plasmid 62 (3), 158-165, 2009 | 16 | 2009 |
| Mycobacterium tuberculosis exploits focal adhesion kinase to induce necrotic cell death and inhibit reactive oxygen species production A Afriyie-Asante, A Dabla, A Dagenais, S Berton, R Smyth, J Sun Frontiers in Immunology 12, 742370, 2021 | 12 | 2021 |
| Protein Kinase R Restricts the Intracellular Survival of Mycobacterium tuberculosis by Promoting Selective Autophagy R Smyth, S Berton, N Rajabalee, T Chan, J Sun Frontiers in Microbiology 11, 613963, 2021 | 10 | 2021 |
Michael NiederweisProfessor of Microbiology, University of Alabama at BirminghamVerified email at uab.edu
