Kenneth Lum
Title
Cited by
Cited by
Year
Proteome-wide covalent ligand discovery in native biological systems
KM Backus, BE Correia, KM Lum, S Forli, BD Horning, GE González-Páez, ...
Nature 534 (7608), 570-574, 2016
3132016
Highly selective inhibitors of monoacylglycerol lipase bearing a reactive group that is bioisosteric with endocannabinoid substrates
JW Chang, MJ Niphakis, KM Lum, AB Cognetta III, C Wang, ML Matthews, ...
Chemistry & biology 19 (5), 579-588, 2012
1672012
A global map of lipid-binding proteins and their ligandability in cells
MJ Niphakis, KM Lum, AB Cognetta III, BE Correia, TA Ichu, J Olucha, ...
Cell 161 (7), 1668-1680, 2015
1272015
An LXR-cholesterol axis creates a metabolic co-dependency for brain cancers
GR Villa, JJ Hulce, C Zanca, J Bi, S Ikegami, GL Cahill, Y Gu, KM Lum, ...
Cancer cell 30 (5), 683-693, 2016
1142016
Chemical proteomic profiling of human methyltransferases
BD Horning, RM Suciu, DA Ghadiri, OA Ulanovskaya, ML Matthews, ...
Journal of the American Chemical Society 138 (40), 13335-13343, 2016
472016
Metabolically labile fumarate esters impart kinetic selectivity to irreversible inhibitors
BW Zaro, LR Whitby, KM Lum, BF Cravatt
Journal of the American Chemical Society 138 (49), 15841-15844, 2016
242016
Carbamate compounds and of making and using same
JS Cisar, CA Grice, TK Jones, MJ Niphakis, JW Chang, KM Lum, ...
US Patent 9,133,148, 2015
202015
Multicomponent mapping of boron chemotypes furnishes selective enzyme inhibitors
J Tan, AB Cognetta Iii, DB Diaz, KM Lum, S Adachi, S Kundu, BF Cravatt, ...
Nature communications 8 (1), 1-8, 2017
182017
Stabilized Wittig olefination for bioconjugation
KM Lum, VJ Xavier, MJH Ong, CW Johannes, KP Chan
Chemical Communications 49 (95), 11188-11190, 2013
172013
Mapping protein targets of bioactive small molecules using lipid-based chemical proteomics
KM Lum, Y Sato, BA Beyer, WC Plaisted, JL Anglin, LL Lairson, ...
ACS chemical biology 12 (10), 2671-2681, 2017
142017
Pharmacological convergence reveals a lipid pathway that regulates C. elegans lifespan
AL Chen, KM Lum, P Lara-Gonzalez, D Ogasawara, AB Cognetta, A To, ...
Nature chemical biology 15 (5), 453-462, 2019
122019
Carbamate compounds and of making and using same
JS Cisar, CA Grice, TK Jones, MJ Niphakis, JW Chang, KM Lum, ...
US Patent 9,487,495, 2016
122016
Single-cell profiling and SCOPE-Seq reveal lineage dynamics of adult ventricular-subventricular zone neurogenesis and NOTUM as a key regulator
D Mizrak, NS Bayin, J Yuan, Z Liu, RM Suciu, MJ Niphakis, N Ngo, ...
Cell reports 31 (12), 107805, 2020
92020
AIG1 and ADTRP are endogenous hydrolases of fatty acid esters of hydroxy fatty acids (FAHFAs) in mice
ME Ertunc, BP Kok, WH Parsons, JG Wang, D Tan, CJ Donaldson, ...
Journal of Biological Chemistry 295 (18), 5891-5905, 2020
72020
Carbamate compounds and methods of making and using same
JS Cisar, CA Grice, TK Jones, MJ Niphakis, JW Chang, KM Lum, ...
US Patent 9,957,242, 2018
72018
Lipid probes and uses thereof
BF Cravatt, MJ Niphakis, K Lum, B Correia, A Cognetta, J Hulce
US Patent 10,168,342, 2019
32019
Carbamate compounds and methods of making and using same
JS Cisar, CA Grice, TK Jones, MJ Niphakis, JW Chang, KM Lum, ...
US Patent App. 15/925,517, 2018
32018
An activity-guided map of electrophile-cysteine interactions in primary human T cells
EV Vinogradova, X Zhang, D Remillard, DC Lazar, RM Suciu, Y Wang, ...
Cell 182 (4), 1009-1026. e29, 2020
22020
3-Oxo-β-sultam as a Sulfonylating Chemotype for Inhibition of Serine Hydrolases and Activity-Based Protein Profiling
LAR Carvalho, VT Almeida, JA Brito, KM Lum, TF Oliveira, RC Guedes, ...
ACS Chemical Biology 15 (4), 878-883, 2020
22020
ABHD17 enzymes regulate dynamic plasma membrane palmitoylation and N-Ras-dependent cancer growth
JR Remsberg, RM Suciu, NA Zambetti, TW Hanigan, AJ Firestone, ...
bioRxiv, 2020
12020
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Articles 1–20