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Kalliopi Tsafou
Kalliopi Tsafou
Data Sciences & Quantitative Biology, AstraZeneca
Adresse e-mail validée de astrazeneca.com
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STRING v10: protein–protein interaction networks, integrated over the tree of life
D Szklarczyk, A Franceschini, S Wyder, K Forslund, D Heller, ...
Nucleic acids research 43 (D1), D447-D452, 2015
99442015
DISEASES: Text mining and data integration of disease–gene associations
S Pletscher-Frankild, A Pallejà, K Tsafou, JX Binder, LJ Jensen
Methods 74, 83-89, 2015
5932015
COMPARTMENTS: unification and visualization of protein subcellular localization evidence
JX Binder, S Pletscher-Frankild, K Tsafou, C Stolte, SI O’Donoghue, ...
Database 2014, 2014
5762014
Autism genes converge on asynchronous development of shared neuron classes
B Paulsen, S Velasco, AJ Kedaigle, M Pigoni, G Quadrato, AJ Deo, ...
Nature 602 (7896), 268-273, 2022
2012022
Targeting intrinsically disordered transcription factors: changing the paradigm
K Tsafou, PB Tiwari, JD Forman-Kay, SJ Metallo, JA Toretsky
Journal of molecular biology 430 (16), 2321-2341, 2018
982018
Comprehensive comparison of large-scale tissue expression datasets
A Santos, K Tsafou, C Stolte, S Pletscher-Frankild, SI O’Donoghue, ...
PeerJ 3, e1054, 2015
942015
Phosphoproteomics of primary cells reveals druggable kinase signatures in ovarian cancer
C Francavilla, M Lupia, K Tsafou, A Villa, K Kowalczyk, ...
Cell reports 18 (13), 3242-3256, 2017
932017
Temporal proteomics of NGF-TrkA signaling identifies an inhibitory role for the E3 ligase Cbl-b in neuroblastoma cell differentiation
KB Emdal, AK Pedersen, DB Bekker-Jensen, KP Tsafou, H Horn, ...
Science signaling 8 (374), ra40-ra40, 2015
812015
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
R Pourhaghighi, PEA Ash, S Phanse, F Goebels, LZM Hu, S Chen, ...
Cell systems 10 (4), 333-350. e14, 2020
592020
The second European interdisciplinary Ewing sarcoma research summit–A joint effort to deconstructing the multiple layers of a complex disease
H Kovar, J Amatruda, E Brunet, S Burdach, F Cidre-Aranaz, E De Alava, ...
Oncotarget 7 (8), 8613, 2016
512016
Reconstruction of the experimentally supported human protein interactome: what can we learn?
MI Klapa, K Tsafou, E Theodoridis, A Tsakalidis, NK Moschonas
BMC systems biology 7, 1-14, 2013
392013
Lapatinib potentiates cytotoxicity of YM155 in neuroblastoma via inhibition of the ABCB1 efflux transporter
B Radic-Sarikas, M Halasz, KVM Huber, GE Winter, KP Tsafou, ...
Scientific Reports 7 (1), 3091, 2017
382017
Combinatorial drug screening identifies Ewing sarcoma–specific sensitivities
B Radic-Sarikas, KP Tsafou, KB Emdal, T Papamarkou, KVM Huber, ...
Molecular Cancer Therapeutics 16 (1), 88-101, 2017
212017
Protein interaction studies in human induced neurons indicate convergent biology underlying autism spectrum disorders
G Pintacuda, YHH Hsu, K Tsafou, KW Li, JM Martín, J Riseman, ...
Cell Genomics 3 (3), 2023
152023
Human brain organoids reveal accelerated development of cortical neuron classes as a shared feature of autism risk genes
B Paulsen, S Velasco, AJ Kedaigle, M Pigoni, G Quadrato, A Deo, ...
BioRxiv, 2020.11. 10.376509, 2020
122020
Identifying the druggable interactome of EWS-FLI1 reveals MCL-1 dependent differential sensitivities of Ewing sarcoma cells to apoptosis inducers
K Tsafou, AM Katschnig, B Radic-Sarikas, CN Mutz, K Iljin, R Schwentner, ...
Oncotarget 9 (57), 31018, 2018
122018
Interaction studies of risk proteins in human induced neurons reveal convergent biology and novel mechanisms underlying autism spectrum disorders
G Pintacuda, YHH Hsu, K Tsafou, KW Li, JM Martín, J Riseman, ...
MedRxiv, 2021.10. 07.21264575, 2021
52021
Using brain cell-type-specific protein interactomes to interpret neurodevelopmental genetic signals in schizophrenia
YHH Hsu, G Pintacuda, R Liu, E Nacu, A Kim, K Tsafou, N Petrossian, ...
Iscience 26 (5), 2023
22023
Using brain cell-type-specific protein interactomes to interpret genetic data in schizophrenia
YHH Hsu, E Nacu, R Liu, G Pintacuda, A Kim, K Tsafou, N Petrossian, ...
medRxiv, 2021.10. 07.21264568, 2021
22021
cGAS-STING signalling regulates microglial chemotaxis in genome instability
EJ Talbot, L Joshi, P Thornton, M Dezfouli, K Tsafou, M Perkinton, ...
Nucleic Acids Research 52 (3), 1188-1206, 2024
12024
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