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Professor Neil Q. Mcdonald
Professor Neil Q. Mcdonald
Senior Group Leader, The Francis Crick Institute
Verified email at crick.ac.uk
Title
Cited by
Cited by
Year
Intratumor heterogeneity and branched evolution revealed by multiregion sequencing
M Gerlinger, AJ Rowan, S Horswell, J Larkin, D Endesfelder, E Gronroos, ...
New England journal of medicine 366 (10), 883-892, 2012
84882012
A structural superfamily of growth factors containing a cystine knot motif
NQ McDonald, WA Hendrickson
Cell 73 (3), 421-424, 1993
8321993
New protein fold revealed by a 2.3-Å resolution crystal structure of nerve growth factor
NQ McDonald, R Lapatto, JM Rust, J Gunning, A Wlodawer, TL Blundell
Nature 354 (6352), 411-414, 1991
6961991
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1
H Plun-Favreau, K Klupsch, N Moisoi, S Gandhi, S Kjaer, D Frith, ...
Nature cell biology 9 (11), 1243-1252, 2007
5722007
Disruption of methylarginine metabolism impairs vascular homeostasis
J Leiper, M Nandi, B Torondel, J Murray-Rust, M Malaki, B O'Hara, ...
Nature medicine 13 (2), 198-203, 2007
4762007
Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM
A Ciccia, C Ling, R Coulthard, Z Yan, Y Xue, AR Meetei, EH Laghmani, ...
Molecular cell 25 (3), 331-343, 2007
4172007
S-nitrosylation of dimethylarginine dimethylaminohydrolase regulates enzyme activity: Further interactions between nitric oxide synthase and dimethylarginine …
J Leiper, J Murray-Rust, N McDonald, P Vallance
Proceedings of the National Academy of Sciences 99 (21), 13527-13532, 2002
3952002
Structure and chemical inhibition of the RET tyrosine kinase domain
PP Knowles, J Murray-Rust, S Kjær, RP Scott, S Hanrahan, M Santoro, ...
Journal of biological chemistry 281 (44), 33577-33587, 2006
3472006
Structural and functional relationships of the XPF/MUS81 family of proteins
A Ciccia, N McDonald, SC West
Annu. Rev. Biochem. 77, 259-287, 2008
3392008
Structural insights into the hydrolysis of cellular nitric oxide synthase inhibitors by dimethylarginine dimethylaminohydrolase
J Murray-Rust, J Leiper, M McAlister, J Phelan, S Tilley, JS Maria, ...
Nature structural biology 8 (8), 679-683, 2001
3172001
The solution structure of the Josephin domain of ataxin-3: structural determinants for molecular recognition
G Nicastro, RP Menon, L Masino, PP Knowles, NQ McDonald, A Pastore
Proceedings of the National Academy of Sciences 102 (30), 10493-10498, 2005
2392005
Epidermal growth factor binding induces a conformational change in the external domain of its receptor.
C Greenfield, I Hiles, MD Waterfield, M Federwisch, A Wollmer, ...
The EMBO journal 8 (13), 4115-4123, 1989
2361989
Topological similarities in TGF-β2, PDGF-BB and NGF define a superfamily of polypeptide growth factors
J Murray-Rust, NQ McDonald, TL Blundell, M Hosang, C Oefner, ...
Structure 1 (2), 153-159, 1993
2181993
A heterozygous effect for PINK1 mutations in Parkinson's disease?
PM Abou‐Sleiman, MMK Muqit, NQ McDonald, YX Yang, S Gandhi, ...
Annals of neurology 60 (4), 414-419, 2006
2062006
The dual mechanism of separase regulation by securin
NCD Hornig, PP Knowles, NQ McDonald, F Uhlmann
Current biology 12 (12), 973-982, 2002
1942002
Crystal structure of the MAPK phosphatase Pyst1 catalytic domain and implications for regulated activation
AE Stewart, S Dowd, SM Keyse, NQ McDonald
Nature structural biology 6 (2), 174-181, 1999
1941999
Crystal structure of dimeric human ciliary neurotrophic factor determined by MAD phasing.
NQ McDonald, N Panayotatos, WA Hendrickson
The EMBO journal 14 (12), 2689-2699, 1995
1941995
Crystal structure of the C2 domain from protein kinase C-δ
H Pappa, J Murray-Rust, LV Dekker, PJ Parker, NQ McDonald
Structure 6 (7), 885-894, 1998
1661998
A small-molecule inhibitor for phosphatase and tensin homologue deleted on chromosome 10 (PTEN)
E Rosivatz, JG Matthews, NQ McDonald, X Mulet, KK Ho, N Lossi, ...
ACS chemical biology 1 (12), 780-790, 2006
1592006
Functional analysis of mutant neurotrophins deficient in low‐affinity binding reveals a role for p75LNGFR in NT‐4 signalling.
M Ryden, J Murray‐Rust, D Glass, LL Ilag, M Trupp, GD Yancopoulos, ...
The EMBO Journal 14 (9), 1979-1990, 1995
1571995
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