Cytochrome P4501A1 Is Required for Vascular Dysfunction and Hypertension Induced by 2,3,7,8-Tetrachlorodibenzo-p-Dioxin PG Kopf, JA Scott, LN Agbor, JR Boberg, KM Elased, JK Huwe, ... Toxicological Sciences 117 (2), 537-546, 2010 | 97 | 2010 |
Arginine vasopressin infusion is sufficient to model clinical features of preeclampsia in mice JA Sandgren, G Deng, DW Linggonegoro, SM Scroggins, ... JCI insight 3 (19), 2018 | 70 | 2018 |
Hypertension-causing mutations in Cullin3 protein impair RhoA protein ubiquitination and augment the association with substrate adaptors SRC Ibeawuchi, LN Agbor, FW Quelle, CD Sigmund Journal of Biological Chemistry 290 (31), 19208-19217, 2015 | 70 | 2015 |
Elevated blood pressure in cytochrome P4501A1 knockout mice is associated with reduced vasodilation to omega− 3 polyunsaturated fatty acids LN Agbor, MT Walsh, JR Boberg, MK Walker Toxicology and applied pharmacology 264 (3), 351-360, 2012 | 65 | 2012 |
Cullin-3 mutation causes arterial stiffness and hypertension through a vascular smooth muscle mechanism LN Agbor, SRC Ibeawuchi, C Hu, J Wu, DR Davis, HL Keen, FW Quelle, ... JCI insight 1 (19), 2016 | 64 | 2016 |
Endothelial cell-specific aryl hydrocarbon receptor knockout mice exhibit hypotension mediated, in part, by an attenuated angiotensin II responsiveness LN Agbor, KM Elased, MK Walker Biochemical pharmacology 82 (5), 514-523, 2011 | 53 | 2011 |
Loss of the aryl hydrocarbon receptor induces hypoxemia, endothelin-1, and systemic hypertension at modest altitude AK Lund, LN Agbor, N Zhang, A Baker, H Zhao, GD Fink, NL Kanagy, ... Hypertension 51 (3), 803-809, 2008 | 51 | 2008 |
Mutant Cullin 3 causes familial hyperkalemic hypertension via dominant effects MZ Ferdaus, LN Miller, LN Agbor, T Saritas, JD Singer, CD Sigmund, ... JCI insight 2 (24), 2017 | 41 | 2017 |
An activated renin–angiotensin system maintains normal blood pressure in aryl hydrocarbon receptor heterozygous mice but not in null mice N Zhang, LN Agbor, JA Scott, T Zalobowski, KM Elased, A Trujillo, ... Biochemical pharmacology 80 (2), 197-204, 2010 | 40 | 2010 |
RhoBTB1 protects against hypertension and arterial stiffness by restraining phosphodiesterase 5 activity M Mukohda, S Fang, J Wu, LN Agbor, AR Nair, SRC Ibeawuchi, C Hu, ... The Journal of clinical investigation 129 (6), 2318-2332, 2019 | 37 | 2019 |
New point mutation in Golga3 causes multiple defects in spermatogenesis LF Bentson, VA Agbor, LN Agbor, AC Lopez, LE Nfonsam, SS Bornstein, ... Andrology 1 (3), 440-450, 2013 | 29 | 2013 |
Conditional deletion of smooth muscle Cullin-3 causes severe progressive hypertension LN Agbor, AR Nair, J Wu, KT Lu, DR Davis, HL Keen, FW Quelle, ... JCI insight 4 (14), 2019 | 28 | 2019 |
Role of CYP1A1 in modulating the vascular and blood pressure benefits of omega-3 polyunsaturated fatty acids LN Agbor, EF Wiest, M Rothe, WH Schunck, MK Walker Journal of Pharmacology and Experimental Therapeutics 351 (3), 688-698, 2014 | 28 | 2014 |
Failure to vasodilate in response to salt loading blunts renal blood flow and causes salt-sensitive hypertension J Wu, LN Agbor, S Fang, M Mukohda, AR Nair, P Nakagawa, A Sharma, ... Cardiovascular research 117 (1), 308-319, 2021 | 23 | 2021 |
Endothelial PPARγ (Peroxisome Proliferator–Activated Receptor-γ) Protects From Angiotensin II–Induced Endothelial Dysfunction in Adult Offspring Born From Pregnancies … AR Nair, SD Silva Jr, LN Agbor, J Wu, P Nakagawa, M Mukohda, KT Lu, ... Hypertension 74 (1), 173-183, 2019 | 21 | 2019 |
Interference with endothelial PPAR (Peroxisome Proliferator–Activated Receptor)-γ causes accelerated cerebral vascular dysfunction in response to Endogenous Renin-Angiotensin … AR Nair, LN Agbor, M Mukohda, X Liu, C Hu, J Wu, CD Sigmund Hypertension 72 (5), 1227-1235, 2018 | 21 | 2018 |
Dual gain and loss of cullin 3 function mediates familial hyperkalemic hypertension RJ Cornelius, C Zhang, KJ Erspamer, LN Agbor, CD Sigmund, JD Singer, ... American Journal of Physiology-Renal Physiology 315 (4), F1006-F1018, 2018 | 21 | 2018 |
Cul3 regulates cyclin E1 protein abundance via a degron located within the N-terminal region of cyclin E B Davidge, KGO Rebola, LN Agbor, CD Sigmund, JD Singer Journal of cell science 132 (21), jcs233049, 2019 | 16 | 2019 |
Increased Susceptibility of Mice Lacking Renin-b to Angiotensin II–Induced Organ Damage P Nakagawa, AR Nair, LN Agbor, J Gomez, J Wu, SY Zhang, KT Lu, ... Hypertension 76 (2), 468-477, 2020 | 9 | 2020 |
819 McCormick JA MZ Ferdaus, LN Miller, LN Agbor, T Saritas, JD Singer, CD Sigmund Mutant Cullin 3, 0 | 9 | |