Shamil Sunyaev
Shamil Sunyaev
Professor of Biomedical Informatics and of Medicine (BWH), Harvard Medical School
Adresse e-mail validée de rics.bwh.harvard.edu - Page d'accueil
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A method and server for predicting damaging missense mutations
IA Adzhubei, S Schmidt, L Peshkin, VE Ramensky, A Gerasimova, P Bork, ...
Nature methods 7 (4), 248-249, 2010
100022010
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project
ENCODE Project Consortium
nature 447 (7146), 799, 2007
52022007
Mutational heterogeneity in cancer and the search for new cancer-associated genes
MS Lawrence, P Stojanov, P Polak, GV Kryukov, K Cibulskis, ...
Nature 499 (7457), 214-218, 2013
38092013
Integrative analysis of 111 reference human epigenomes
A Kundaje, W Meuleman, J Ernst, M Bilenky, A Yen, A Heravi-Moussavi, ...
Nature 518 (7539), 317-330, 2015
35302015
Systematic localization of common disease-associated variation in regulatory DNA
MT Maurano, R Humbert, E Rynes, RE Thurman, E Haugen, H Wang, ...
Science 337 (6099), 1190-1195, 2012
24732012
Human non‐synonymous SNPs: server and survey
V Ramensky, P Bork, S Sunyaev
Nucleic acids research 30 (17), 3894-3900, 2002
24382002
The accessible chromatin landscape of the human genome
RE Thurman, E Rynes, R Humbert, J Vierstra, MT Maurano, E Haugen, ...
Nature 489 (7414), 75-82, 2012
22502012
Predicting functional effect of human missense mutations using PolyPhen‐2
I Adzhubei, DM Jordan, SR Sunyaev
Current protocols in human genetics 76 (1), 7.20. 1-7.20. 41, 2013
19182013
Patterns and rates of exonic de novo mutations in autism spectrum disorders
BM Neale, Y Kou, L Liu, A Ma’Ayan, KE Samocha, A Sabo, CF Lin, ...
Nature 485 (7397), 242-245, 2012
16322012
Evolution and functional impact of rare coding variation from deep sequencing of human exomes
JA Tennessen, AW Bigham, TD O’Connor, W Fu, EE Kenny, S Gravel, ...
science 337 (6090), 64-69, 2012
15442012
The mystery of missing heritability: Genetic interactions create phantom heritability
O Zuk, E Hechter, SR Sunyaev, ES Lander
Proceedings of the National Academy of Sciences 109 (4), 1193-1198, 2012
14912012
Prediction of deleterious human alleles
S Sunyaev, V Ramensky, I Koch, W Lathe III, AS Kondrashov, P Bork
Human molecular genetics 10 (6), 591-597, 2001
12052001
The ‘Shp'ing news: SH2 domain-containing tyrosine phosphatases in cell signaling
BG Neel, H Gu, L Pao
Trends in biochemical sciences 28 (6), 284-293, 2003
12002003
Guidelines for investigating causality of sequence variants in human disease
DG MacArthur, TA Manolio, DP Dimmock, HL Rehm, J Shendure, ...
Nature 508 (7497), 469-476, 2014
10352014
Pooled association tests for rare variants in exon-resequencing studies
AL Price, GV Kryukov, PIW de Bakker, SM Purcell, J Staples, LJ Wei, ...
The American Journal of Human Genetics 86 (6), 832-838, 2010
7942010
Charting the proteomes of organisms with unsequenced genomes by MALDI-quadrupole time-of-flight mass spectrometry and BLAST homology searching
A Shevchenko, S Sunyaev, A Loboda, A Shevchenko, P Bork, W Ens, ...
Analytical chemistry 73 (9), 1917-1926, 2001
6702001
Most rare missense alleles are deleterious in humans: implications for complex disease and association studies
GV Kryukov, LA Pennacchio, SR Sunyaev
The American Journal of Human Genetics 80 (4), 727-739, 2007
6042007
Genomic variation landscape of the human gut microbiome
S Schloissnig, M Arumugam, S Sunagawa, M Mitreva, J Tap, A Zhu, ...
Nature 493 (7430), 45-50, 2013
5902013
Assessing the evolutionary impact of amino acid mutations in the human genome
AR Boyko, SH Williamson, AR Indap, JD Degenhardt, RD Hernandez, ...
PLoS Genet 4 (5), e1000083, 2008
5802008
Searching for missing heritability: designing rare variant association studies
O Zuk, SF Schaffner, K Samocha, R Do, E Hechter, S Kathiresan, MJ Daly, ...
Proceedings of the National Academy of Sciences 111 (4), E455-E464, 2014
5252014
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