| Targeting CD39 in cancer reveals an extracellular ATP-and inflammasome-driven tumor immunity XY Li, AK Moesta, C Xiao, K Nakamura, M Casey, H Zhang, J Madore, ... Cancer discovery 9 (12), 1754-1773, 2019 | 206 | 2019 |
| Hormonal control of T-cell development in health and disease W Savino, DA Mendes-da-Cruz, A Lepletier, M Dardenne Nature Reviews Endocrinology 12 (2), 77-89, 2016 | 135 | 2016 |
| CD155 loss enhances tumor suppression via combined host and tumor-intrinsic mechanisms XY Li, I Das, A Lepletier, V Addala, T Bald, K Stannard, D Barkauskas, ... The Journal of clinical investigation 128 (6), 2613-2625, 2018 | 114 | 2018 |
| CD155 on tumor cells drives resistance to immunotherapy by inducing the degradation of the activating receptor CD226 in CD8+ T cells M Braun, AR Aguilera, A Sundarrajan, D Corvino, K Stannard, S Krumeich, ... Immunity 53 (4), 805-823. e15, 2020 | 95 | 2020 |
| CD96 Is an Immune Checkpoint That Regulates CD8+ T-cell Antitumor Function D Mittal, A Lepletier, J Madore, AR Aguilera, K Stannard, SJ Blake, ... Cancer immunology research 7 (4), 559-571, 2019 | 90 | 2019 |
| Tumor CD155 expression is associated with resistance to anti-PD1 immunotherapy in metastatic melanoma A Lepletier, J Madore, JS O'Donnell, RL Johnston, XY Li, E McDonald, ... Clinical Cancer Research 26 (14), 3671-3681, 2020 | 68 | 2020 |
| Interplay between follistatin, activin A, and BMP4 signaling regulates postnatal thymic epithelial progenitor cell differentiation during aging A Lepletier, ML Hun, MV Hammett, K Wong, H Naeem, M Hedger, ... Cell reports 27 (13), 3887-3901. e4, 2019 | 56 | 2019 |
| TNF-α is involved in the abnormal thymocyte migration during experimental Trypanosoma cruzi infection and favors the export of immature cells AR Pérez, LR Berbert, A Lepletier, S Revelli, O Bottasso, ... PLoS One 7 (3), e34360, 2012 | 46 | 2012 |
| The immune checkpoint CD96 defines a distinct lymphocyte phenotype and is highly expressed on tumor‐infiltrating T cells A Lepletier, VP Lutzky, D Mittal, K Stannard, TS Watkins, CN Ratnatunga, ... Immunology and cell biology 97 (2), 152-164, 2019 | 38 | 2019 |
| Tumor Necrosis Factor-α Regulates Glucocorticoid Synthesis in the Adrenal Glands of Trypanosoma cruzi Acutely-Infected Mice. The Role of TNF-R1 SR Villar, MT Ronco, R Fernández Bussy, E Roggero, A Lepletier, ... PLoS One 8 (5), e63814, 2013 | 38 | 2013 |
| Thymic atrophy in acute experimental Chagas disease is associated with an imbalance of stress hormones A Lepletier, V de Frias Carvalho, A Morrot, W Savino Annals of the New York Academy of Sciences 1262 (1), 45-50, 2012 | 38 | 2012 |
| Trypanosoma cruzi Disrupts Thymic Homeostasis by Altering Intrathymic and Systemic Stress-Related Endocrine Circuitries A Lepletier, VF de Carvalho, PMR e Silva, S Villar, AR Perez, W Savino, ... PLoS Neglected Tropical Diseases 7 (11), e2470, 2013 | 35 | 2013 |
| Perspectives for improvement of the thymic microenvironment through manipulation of thymic epithelial cells: a mini-review A Lepletier, AP Chidgey, W Savino Gerontology 61 (6), 504-514, 2015 | 33 | 2015 |
| Early Double-Negative Thymocyte Export in Trypanosoma cruzi Infection Is Restricted by Sphingosine Receptors and Associated with Human Chagas Disease A Lepletier, L de Almeida, L Santos, L da Silva Sampaio, B Paredes, ... PLoS Neglected Tropical Diseases 8 (10), e3203, 2014 | 33 | 2014 |
| A novel Foxn1eGFP/+ mouse model identifies Bmp4‐induced maintenance of Foxn1 expression and thymic epithelial progenitor populations M Barsanti, JMC Lim, ML Hun, N Lister, K Wong, MV Hammett, A Lepletier, ... European Journal of Immunology 47 (2), 291-304, 2017 | 30 | 2017 |
| Inflammation and thymus ageing A Lepletier, A Alsharif, AP Chidgey Endocrine Immunology 48, 19-36, 2017 | 22 | 2017 |
| CD96 is an immune checkpoint that regulates CD8 (+) T-cell antitumor function. Cancer Immunol Res. 2019; 7: 559–571. doi: 10.1158/2326-6066 D Mittal, A Lepletier, J Madore, AR Aguilera, K Stannard, SJ Blake, ... CIR-18-0637.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0 | 19 | |
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| A primary human T-cell spectral library to facilitate large scale quantitative T-cell proteomics H Weerakoon, J Potriquet, AK Shah, S Reed, B Jayakody, C Kapil, ... Scientific data 7 (1), 412, 2020 | 12 | 2020 |
| Small interference ITGA6 gene targeting in the human thymic epithelium differentially regulates the expression of immunological synapse-related genes DCF Golbert, E Santana-Van-Vliet, M Ribeiro-Alves, MMB Fonsêca, ... Cell adhesion & migration 12 (2), 152-167, 2018 | 10 | 2018 |
