| Role for Runx1 in the proliferation and neuronal differentiation of selected progenitor cells in the mammalian nervous system FM Theriault, HN Nuthall, Z Dong, R Lo, F Barnabe-Heider, FD Miller, ... Journal of Neuroscience 25 (8), 2050-2061, 2005 | 135 | 2005 |
| Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation … M Keatinge, H Bui, A Menke, YC Chen, AM Sokol, Q Bai, F Ellett, ... Human molecular genetics 24 (23), 6640-6652, 2015 | 132 | 2015 |
| A Regulatory Element in Intron 1 of the Cystic Fibrosis Transmembrane Conductance Regulator Gene (∗) AN Smith, ML Barth, TL McDowell, DS Moulin, HN Nuthall, ... Journal of Biological Chemistry 271 (17), 9947-9954, 1996 | 95 | 1996 |
| Phosphorylation of serine 239 of Groucho/TLE1 by protein kinase CK2 is important for inhibition of neuronal differentiation HN Nuthall, K Joachim, S Stifani Molecular and cellular biology 24 (19), 8395-8407, 2004 | 74 | 2004 |
| Role for Hes1-induced phosphorylation in Groucho-mediated transcriptional repression HN Nuthall, J Husain, KW McLarren, S Stifani Molecular and cellular biology 22 (2), 389-399, 2002 | 73 | 2002 |
| Multiple potential intragenic regulatory elements in the CFTR gene DJ Smith, HN Nuthall, ME Majetti, A Harris Genomics 64 (1), 90-96, 2000 | 63 | 2000 |
| Analysis of DNase-I-hypersensitive sites at the 3′ end of the cystic fibrosis transmembrane conductance regulator gene (CFTR) HN Nuthall, DS Moulin, C Huxley, A Harris Biochemical Journal 341 (3), 601-611, 1999 | 58 | 1999 |
| Evidence for an enhancement of excitatory transmission in adult CNS by Wnt signaling pathway modulation V Beaumont, SA Thompson, F Choudhry, H Nuthall, H Glantschnig, ... Molecular and Cellular Neuroscience 35 (4), 513-524, 2007 | 57 | 2007 |
| Evaluation of potential regulatory elements identified as DNase I hypersensitive sites in the CFTR gene M Phylactides, R Rowntree, H Nuthall, D Ussery, A Wheeler, A Harris European journal of biochemistry 269 (2), 553-559, 2002 | 52 | 2002 |
| A role for cell cycle-regulated phosphorylation in Groucho-mediated transcriptional repression HN Nuthall, K Joachim, A Palaparti, S Stifani Journal of Biological Chemistry 277 (52), 51049-51057, 2002 | 39 | 2002 |
| The microglial P2Y6 receptor mediates neuronal loss and memory deficits in neurodegeneration M Puigdellívol, S Milde, A Vilalta, TOJ Cockram, DH Allendorf, JY Lee, ... Cell Reports 37 (13), 2021 | 37 | 2021 |
| Analysis of a DNase I hypersensitive site located −20.9 kb upstream of the CFTR gene HN Nuthall, G Vassaux, C Huxley, A Harris European journal of biochemistry 266 (2), 431-443, 1999 | 33 | 1999 |
| Development of a characterised tool kit for the interrogation of NLRP3 inflammasome-dependent responses E Redondo-Castro, D Faust, S Fox, AG Baldwin, S Osborne, MJ Haley, ... Scientific reports 8 (1), 5667, 2018 | 29 | 2018 |
| Evaluation of a PET radioligand to image O-GlcNAcase in brain and periphery of rhesus monkey and knock-out mouse S Paul, MB Haskali, JS Liow, SS Zoghbi, VN Barth, MC Kolodrubetz, ... Journal of Nuclear Medicine 60 (1), 129-134, 2019 | 28 | 2019 |
| Triazoles as γ-secretase modulators C Fischer, SL Zultanski, H Zhou, JL Methot, WC Brown, DM Mampreian, ... Bioorganic & medicinal chemistry letters 21 (13), 4083-4087, 2011 | 25 | 2011 |
| Inhibition of IL-34 unveils tissue-selectivity and is sufficient to reduce microglial proliferation in a model of chronic neurodegeneration J Obst, E Simon, M Martin-Estebane, E Pipi, LM Barkwill, ... Frontiers in immunology 11, 579000, 2020 | 24 | 2020 |
| PET ligands [18F]LSN3316612 and [11C]LSN3316612 quantify O-linked-β-N-acetyl-glucosamine hydrolase in the brain S Lu, MB Haskali, KM Ruley, NJF Dreyfus, SL DuBois, S Paul, JS Liow, ... Science translational medicine 12 (543), eaau2939, 2020 | 23 | 2020 |
| In Vivo Analysis of DNase I Hypersensitive Sites in the Human CFTR Gene DS Moulin, AL Manson, HN Nuthall, DJ Smith, C Huxley, A Harris Molecular Medicine 5, 211-223, 1999 | 23 | 1999 |
| PET quantification of brain O-GlcNAcase with [18F]LSN3316612 in healthy human volunteers JH Lee, JS Liow, S Paul, CL Morse, MB Haskali, L Manly, S Shcherbinin, ... EJNMMI research 10, 1-12, 2020 | 18 | 2020 |
| Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors JD Katz, A Haidle, KK Childers, AA Zabierek, JP Jewell, Y Hou, ... Bioorganic & medicinal chemistry letters 27 (1), 114-120, 2017 | 18 | 2017 |
