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Geoffrey G Hesketh
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A proximity-dependent biotinylation map of a human cell
CD Go, JDR Knight, A Rajasekharan, B Rathod, GG Hesketh, KT Abe, ...
Nature 595 (7865), 120-124, 2021
2742021
Dynamic changes in conduction velocity and gap junction properties during development of pacing-induced heart failure
FG Akar, RD Nass, S Hahn, E Cingolani, M Shah, GG Hesketh, ...
American Journal of Physiology-Heart and Circulatory Physiology, 2007
2332007
Electrophysiological consequences of dyssynchronous heart failure and its restoration by resynchronization therapy
T Aiba, GG Hesketh, AS Barth, T Liu, S Daya, K Chakir, VL Dimaano, ...
Circulation 119 (9), 1220-1230, 2009
2312009
Cyclic GMP/PKG-dependent inhibition of TRPC6 channel activity and expression negatively regulates cardiomyocyte NFAT activation: Novel mechanism of cardiac stress modulation by …
N Koitabashi, T Aiba, GG Hesketh, J Rowell, M Zhang, E Takimoto, ...
Journal of molecular and cellular cardiology 48 (4), 713-724, 2010
1982010
Ultrastructure and regulation of lateralized connexin43 in the failing heart
GG Hesketh, MH Shah, VL Halperin, CA Cooke, FG Akar, TE Yen, ...
Circulation research 106 (6), 1153-1163, 2010
1742010
Na+ channel regulation by Ca2+/calmodulin and Ca2+/calmodulin-dependent protein kinase II in guinea-pig ventricular myocytes
T Aiba, GG Hesketh, T Liu, R Carlisle, MC Villa-Abrille, B O'Rourke, ...
Cardiovascular research 85 (3), 454-463, 2010
1352010
VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface
GG Hesketh, I Pérez-Dorado, LP Jackson, L Wartosch, IB Schäfer, ...
Developmental cell 29 (5), 591-606, 2014
1242014
Cap-binding protein 4EHP effects translation silencing by microRNAs
C Chapat, SM Jafarnejad, E Matta-Camacho, GG Hesketh, IA Gelbart, ...
Proceedings of the National Academy of Sciences 114 (21), 5425-5430, 2017
1202017
RME-8 coordinates the activity of the WASH complex with the function of the retromer SNX dimer to control endosomal tubulation
CL Freeman, G Hesketh, MNJ Seaman
Journal of cell science 127 (9), 2053-2070, 2014
1182014
A 14‐3‐3 mode‐1 binding motif initiates gap junction internalization during acute cardiac ischemia
JW Smyth, SS Zhang, JM Sanchez, S Lamouille, JM Vogan, GG Hesketh, ...
Traffic 15 (6), 684-699, 2014
962014
BLOC-1 and BLOC-3 regulate VAMP7 cycling to and from melanosomes via distinct tubular transport carriers
MK Dennis, C Delevoye, A Acosta-Ruiz, I Hurbain, M Romao, GG Hesketh, ...
Journal of Cell Biology 214 (3), 293-308, 2016
842016
The binding of Varp to VAMP7 traps VAMP7 in a closed, fusogenically inactive conformation
IB Schäfer, GG Hesketh, NA Bright, SR Gray, PR Pryor, PR Evans, ...
Nature structural & molecular biology 19 (12), 1300-1309, 2012
832012
IK1 Heterogeneity Affects Genesis and Stability of Spiral Waves in Cardiac Myocyte Monolayers
RB Sekar, E Kizana, HC Cho, JM Molitoris, GG Hesketh, BP Eaton, ...
Circulation research 104 (3), 355-364, 2009
822009
The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9
BT Emmer, GG Hesketh, E Kotnik, VT Tang, PJ Lascuna, J Xiang, ...
Elife 7, e38839, 2018
802018
Parallel exploration of interaction space by BioID and affinity purification coupled to mass spectrometry
GG Hesketh, JY Youn, P Samavarchi-Tehrani, B Raught, AC Gingras
Proteomics: Methods and Protocols, 115-136, 2017
772017
Mechanisms of gap junction traffic in health and disease
GG Hesketh, JE Van Eyk, GF Tomaselli
Journal of cardiovascular pharmacology 54 (4), 263-272, 2009
702009
Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo
R Khoriaty, GG Hesketh, A Bernard, AC Weyand, D Mellacheruvu, G Zhu, ...
Proceedings of the National Academy of Sciences 115 (33), E7748-E7757, 2018
662018
The GATOR–Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids
GG Hesketh, F Papazotos, J Pawling, D Rajendran, JDR Knight, ...
Science 370 (6514), 351-356, 2020
582020
A proximity biotinylation map of a human cell
CD Go, JDR Knight, A Rajasekharan, B Rathod, GG Hesketh, KT Abe, ...
BioRxiv, 796391, 2019
582019
Translational control of ERK signaling through miRNA/4EHP-directed silencing
SM Jafarnejad, C Chapat, E Matta-Camacho, IA Gelbart, GG Hesketh, ...
Elife 7, e35034, 2018
522018
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