Ben Sidders
Ben Sidders
Oncology R&D, Astrazeneca
Verified email at
Cited by
Cited by
Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon
N Shimono, L Morici, N Casali, S Cantrell, B Sidders, S Ehrt, LW Riley
Proceedings of the national academy of sciences 100 (26), 15918-15923, 2003
A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis
SL Kendall, M Withers, CN Soffair, NJ Moreland, S Gurcha, B Sidders, ...
Molecular microbiology 65 (3), 684-699, 2007
Ion Channels as Therapeutic Targets: A Drug Discovery Perspective
SK Bagal, AD Brown, PJ Cox, K Omoto, RM Owen, DC Pryde, B Sidders, ...
Journal of Medicinal Chemistry, 2012
Causal reasoning on biological networks: interpreting transcriptional changes
L Chindelevitch, D Ziemek, A Enayetallah, R Randhawa, B Sidders, ...
Bioinformatics 28 (8), 1114-1121, 2012
Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex
B Sidders, C Pirson, PJ Hogarth, RG Hewinson, NG Stoker, ...
Infection and immunity 76 (9), 3932-3939, 2008
Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice
RH Senaratne, B Sidders, P Sequeira, G Saunders, K Dunphy, ...
Journal of medical microbiology 57 (2), 164-170, 2008
5′‐Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice
RH Senaratne, AD De Silva, SJ Williams, JD Mougous, JR Reader, ...
Molecular microbiology 59 (6), 1744-1753, 2006
HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain
F Denk, W Huang, B Sidders, A Bithell, M Crow, J Grist, S Sharma, ...
PAIN« 154 (9), 1668-1679, 2013
Genes contributing to pain sensitivity in the normal population: an exome sequencing study
FMK Williams, S Scollen, D Cao, Y Memari, CL Hyde, B Zhang, B Sidders, ...
PLoS Genet 8 (12), e1003095, 2012
Selection, optimization, and pharmacokinetic properties of a novel, potent antiviral locked nucleic acid-based antisense oligomer targeting hepatitis C virus internal ribosomeá…
C Laxton, K Brady, S Moschos, P Turnpenny, J Rawal, DC Pryde, ...
Antimicrobial agents and chemotherapy 55 (7), 3105-3114, 2011
Quantification of global transcription patterns in prokaryotes using spotted microarrays
B Sidders, M Withers, SL Kendall, J Bacon, SJ Waddell, J Hinds, P Golby, ...
Genome biology 8 (12), 1-13, 2007
Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks
CT Fakhry, P Choudhary, A Gutteridge, B Sidders, P Chen, D Ziemek, ...
BMC bioinformatics 17 (1), 1-15, 2016
The pain interactome: connecting pain-specific protein interactions
DG Jamieson, A Moss, M Kennedy, S Jones, G Nenadic, DL Robertson, ...
PAIN« 155 (11), 2243-2252, 2014
Enhanced mortality despite control of lung infection in mice aerogenically infected with a Mycobacterium tuberculosis mce1 operon mutant
P Lima, B Sidders, L Morici, R Reader, R Senaratne, N Casali, LW Riley
Microbes and infection 9 (11), 1285-1290, 2007
Deep sequencing insights in therapeutic shRNA processing and siRNA target cleavage precision
H Denise, SA Moschos, B Sidders, F Burden, H Perkins, N Carter, ...
Molecular Therapy-Nucleic Acids 3, e145, 2014
PI3Kα/δ inhibition promotes anti-tumor immunity through direct enhancement of effector CD8+ T-cell activity
LS Carnevalli, C Sinclair, MA Taylor, PM Gutierrez, S Langdon, ...
Journal for immunotherapy of cancer 6 (1), 1-14, 2018
Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age‐associated neurogenic decline
G Lupo, PS Nisi, P Esteve, YL Paul, CL Novo, B Sidders, MA Khan, ...
Aging Cell 17 (3), e12745, 2018
An integrated transcriptomic and meta-analysis of hepatoma cells reveals factors that influence susceptibility to HCV infection
JI MacPherson, B Sidders, S Wieland, J Zhong, P Targett-Adams, ...
Plos one 6 (10), e25584, 2011
Precompetitive activity to address the biological data needs of drug discovery
B Sidders, C Brockel, A Gutteridge, L Harland, PG Jansen, R McEwen, ...
Nature Reviews Drug Discovery 13 (2), 83-84, 2014
Network-based drug discovery: coupling network pharmacology with phenotypic screening for neuronal excitability
B Sidders, A Karlsson, L Kitching, R Torella, P Karila, A Phelan
Journal of molecular biology 430 (18), 3005-3015, 2018
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