Hypervirulent mutant of Mycobacterium tuberculosis resulting from disruption of the mce1 operon N Shimono, L Morici, N Casali, S Cantrell, B Sidders, S Ehrt, LW Riley Proceedings of the national academy of sciences 100 (26), 15918-15923, 2003 | 227 | 2003 |
A highly conserved transcriptional repressor controls a large regulon involved in lipid degradation in Mycobacterium smegmatis and Mycobacterium tuberculosis SL Kendall, M Withers, CN Soffair, NJ Moreland, S Gurcha, B Sidders, ... Molecular microbiology 65 (3), 684-699, 2007 | 213 | 2007 |
Ion Channels as Therapeutic Targets: A Drug Discovery Perspective SK Bagal, AD Brown, PJ Cox, K Omoto, RM Owen, DC Pryde, B Sidders, ... Journal of Medicinal Chemistry, 2012 | 205 | 2012 |
Causal reasoning on biological networks: interpreting transcriptional changes L Chindelevitch, D Ziemek, A Enayetallah, R Randhawa, B Sidders, ... Bioinformatics 28 (8), 1114-1121, 2012 | 118 | 2012 |
Screening of highly expressed mycobacterial genes identifies Rv3615c as a useful differential diagnostic antigen for the Mycobacterium tuberculosis complex B Sidders, C Pirson, PJ Hogarth, RG Hewinson, NG Stoker, ... Infection and immunity 76 (9), 3932-3939, 2008 | 101 | 2008 |
Mycobacterium tuberculosis strains disrupted in mce3 and mce4 operons are attenuated in mice RH Senaratne, B Sidders, P Sequeira, G Saunders, K Dunphy, ... Journal of medical microbiology 57 (2), 164-170, 2008 | 101 | 2008 |
5′‐Adenosinephosphosulphate reductase (CysH) protects Mycobacterium tuberculosis against free radicals during chronic infection phase in mice RH Senaratne, AD De Silva, SJ Williams, JD Mougous, JR Reader, ... Molecular microbiology 59 (6), 1744-1753, 2006 | 100 | 2006 |
HDAC inhibitors attenuate the development of hypersensitivity in models of neuropathic pain F Denk, W Huang, B Sidders, A Bithell, M Crow, J Grist, S Sharma, ... PAIN® 154 (9), 1668-1679, 2013 | 95 | 2013 |
Genes contributing to pain sensitivity in the normal population: an exome sequencing study FMK Williams, S Scollen, D Cao, Y Memari, CL Hyde, B Zhang, B Sidders, ... PLoS Genet 8 (12), e1003095, 2012 | 61 | 2012 |
Selection, optimization, and pharmacokinetic properties of a novel, potent antiviral locked nucleic acid-based antisense oligomer targeting hepatitis C virus internal ribosome … C Laxton, K Brady, S Moschos, P Turnpenny, J Rawal, DC Pryde, ... Antimicrobial agents and chemotherapy 55 (7), 3105-3114, 2011 | 42 | 2011 |
Quantification of global transcription patterns in prokaryotes using spotted microarrays B Sidders, M Withers, SL Kendall, J Bacon, SJ Waddell, J Hinds, P Golby, ... Genome biology 8 (12), 1-13, 2007 | 39 | 2007 |
Interpreting transcriptional changes using causal graphs: new methods and their practical utility on public networks CT Fakhry, P Choudhary, A Gutteridge, B Sidders, P Chen, D Ziemek, ... BMC bioinformatics 17 (1), 1-15, 2016 | 31 | 2016 |
The pain interactome: connecting pain-specific protein interactions DG Jamieson, A Moss, M Kennedy, S Jones, G Nenadic, DL Robertson, ... PAIN® 155 (11), 2243-2252, 2014 | 25 | 2014 |
Enhanced mortality despite control of lung infection in mice aerogenically infected with a Mycobacterium tuberculosis mce1 operon mutant P Lima, B Sidders, L Morici, R Reader, R Senaratne, N Casali, LW Riley Microbes and infection 9 (11), 1285-1290, 2007 | 25 | 2007 |
Deep sequencing insights in therapeutic shRNA processing and siRNA target cleavage precision H Denise, SA Moschos, B Sidders, F Burden, H Perkins, N Carter, ... Molecular Therapy-Nucleic Acids 3, e145, 2014 | 23 | 2014 |
PI3Kα/δ inhibition promotes anti-tumor immunity through direct enhancement of effector CD8+ T-cell activity LS Carnevalli, C Sinclair, MA Taylor, PM Gutierrez, S Langdon, ... Journal for immunotherapy of cancer 6 (1), 1-14, 2018 | 20 | 2018 |
Molecular profiling of aged neural progenitors identifies Dbx2 as a candidate regulator of age‐associated neurogenic decline G Lupo, PS Nisi, P Esteve, YL Paul, CL Novo, B Sidders, MA Khan, ... Aging Cell 17 (3), e12745, 2018 | 19 | 2018 |
An integrated transcriptomic and meta-analysis of hepatoma cells reveals factors that influence susceptibility to HCV infection JI MacPherson, B Sidders, S Wieland, J Zhong, P Targett-Adams, ... Plos one 6 (10), e25584, 2011 | 19 | 2011 |
Precompetitive activity to address the biological data needs of drug discovery B Sidders, C Brockel, A Gutteridge, L Harland, PG Jansen, R McEwen, ... Nature Reviews Drug Discovery 13 (2), 83-84, 2014 | 17 | 2014 |
Network-based drug discovery: coupling network pharmacology with phenotypic screening for neuronal excitability B Sidders, A Karlsson, L Kitching, R Torella, P Karila, A Phelan Journal of molecular biology 430 (18), 3005-3015, 2018 | 16 | 2018 |