Measurement of lactate levels in postmortem brain, iPSCs, and animal models of schizophrenia CR Sullivan, CA Mielnik, A Funk, SM O’Donovan, E Bentea, M Pletnikov, ... Scientific reports 9 (1), 5087, 2019 | 62 | 2019 |
Prefrontal Cortex-Mediated Impairments in a Genetic Model of NMDA Receptor Hypofunction Are Reversed by the Novel M1 PAM VU6004256 MD Grannan, CA Mielnik, SP Moran, RW Gould, J Ball, Z Lu, M Bubser, ... ACS chemical neuroscience 7 (12), 1706-1716, 2016 | 49 | 2016 |
NMDA receptor‐deficient mice display sexual dimorphism in the onset and severity of behavioural abnormalities M Milenkovic, CA Mielnik, AJ Ramsey Genes, Brain and Behavior 13 (8), 850-862, 2014 | 47 | 2014 |
Connectivity analyses of bioenergetic changes in schizophrenia: identification of novel treatments CR Sullivan, CA Mielnik, SM O’Donovan, AJ Funk, E Bentea, ... Molecular neurobiology 56, 4492-4517, 2019 | 42 | 2019 |
Consequences of NMDA receptor deficiency can be rescued in the adult brain CA Mielnik, MA Binko, Y Chen, AJ Funk, EM Johansson, K Intson, ... Molecular Psychiatry 26 (7), 2929-2942, 2021 | 41 | 2021 |
Postsynaptic density-95 isoform abnormalities in schizophrenia AJ Funk, CA Mielnik, R Koene, E Newburn, AJ Ramsey, BK Lipska, ... Schizophrenia bulletin 43 (4), 891-899, 2017 | 34 | 2017 |
Sustained N‐methyl‐d‐aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling MJ Ferris, M Milenkovic, S Liu, CA Mielnik, P Beerepoot, CE John, ... European Journal of Neuroscience 40 (1), 2255-2263, 2014 | 25 | 2014 |
Diazepam improves aspects of social behaviour and neuron activation in NMDA receptor‐deficient mice CA Mielnik, W Horsfall, AJ Ramsey Genes, Brain and Behavior 13 (7), 592-602, 2014 | 22 | 2014 |
CB1 allosteric modulators and their therapeutic potential in CNS disorders CA Mielnik, VM Lam, RA Ross Progress in Neuro-Psychopharmacology and Biological Psychiatry 106, 110163, 2021 | 20 | 2021 |
A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models CA Mielnik, KS Sugamori, DB Finlay, HHA Thorpe, M Schapira, ... Neuropsychopharmacology 46 (2), 413-422, 2021 | 11 | 2021 |
Behavioral effects of a potential novel TAAR1 antagonist VM Lam, CA Mielnik, C Baimel, P Beerepoot, S Espinoza, I Sukhanov, ... Frontiers in pharmacology 9, 953, 2018 | 9 | 2018 |
Deficits in integrative NMDA receptors caused by Grin1 disruption can be rescued in adulthood S Venkatesan, MA Binko, CA Mielnik, AJ Ramsey, EK Lambe Neuropsychopharmacology 48 (12), 1742-1751, 2023 | 3 | 2023 |
12.2 metabolic consequences of developmental NMDA receptor hypofunction A Funk, C Mielnik, S O’Donovan, C Sullivan, Y Chen, R McCullumsmith, ... Schizophrenia Bulletin 44 (Suppl 1), S19, 2018 | 2 | 2018 |
Cannabidiol, but not Δ9-tetrahydrocannabinol, has strain-and genotype-specific effects in models of psychosis CA Mielnik, CK Li, AJ Ramsey, A Salahpour, WMI Burnham, RA Ross Cannabis and Cannabinoid Research 9 (1), 174-187, 2024 | 1 | 2024 |
P475. Acute Monoacylglycerol Lipase (MAGL) Inhibition Exacerbates Hyperdopaminergic Behavioural Domains: Implications for 2-AG Modulation in Psychosis C Mielnik, C Lutelmowski, C Johnson, J Zebarth, M Milenkovic, W Horsfall, ... Biological Psychiatry 91 (9), S281, 2022 | 1 | 2022 |
The behavioral effects of CBD and THC in mouse models of psychosis CK Li, CA Mielnik, AJ Ramsey, RA Ross, WM Burnham Clinical Neurophysiology 130 (8), e119, 2019 | 1 | 2019 |
The Bidirectional Effect of 2-AG on Hyperdopaminergic States: Implications for Therapeutic 2-AG Modulation in Psychosis C Mielnik, C Lutelmowski, C Johnson, J Zebarth, J Tong, A Pees, ... NEUROPSYCHOPHARMACOLOGY 48, 389-389, 2023 | | 2023 |
Connecting NMDA Receptor Disruption to a Specific Aberration in Prefrontal Cortical Neurophysiology Essential for Executive Function M Binko, C Mielnik, A Ramsey, E Lambe NEUROPSYCHOPHARMACOLOGY 42, S432-S432, 2017 | | 2017 |
GluN1 Hypomorph Disrupts Synaptic Protein-Protein Interactions A Funk, G Labilloy, C Mielnik, R Meeks, K Greis, J Meller, A Ramsey, ... NEUROPSYCHOPHARMACOLOGY 43, S229-S230, 2017 | | 2017 |
Inducible Rescue of N-methyl-d-Aspartate Receptor Deficiency to Study Brain Plasticity C Mielnik University of Toronto (Canada), 2017 | | 2017 |