Mathieu Lupien, Ph.D.
Mathieu Lupien, Ph.D.
Senior Scientist/Professor, Princess Margaret Cancer Centre
Verified email at - Homepage
Cited by
Cited by
FoxA1 translates epigenetic signatures into enhancer-driven lineage-specific transcription
M Lupien, J Eeckhoute, CA Meyer, Q Wang, Y Zhang, W Li, JS Carroll, ...
Cell 132 (6), 958-970, 2008
Androgen receptor regulates a distinct transcription program in androgen-independent prostate cancer
Q Wang, W Li, Y Zhang, X Yuan, K Xu, J Yu, Z Chen, R Beroukhim, ...
Cell 138 (2), 245-256, 2009
Epigenomic alterations define lethal CIMP-positive ependymomas of infancy
SC Mack, H Witt, RM Piro, L Gu, S Zuyderduyn, AM Stütz, X Wang, ...
Nature 506 (7489), 445-450, 2014
Nucleosome dynamics define transcriptional enhancers
HH He, CA Meyer, H Shin, ST Bailey, G Wei, Q Wang, Y Zhang, K Xu, ...
Nature genetics 42 (4), 343-347, 2010
Genomic hallmarks of localized, non-indolent prostate cancer
M Fraser, VY Sabelnykova, TN Yamaguchi, LE Heisler, J Livingstone, ...
Nature 541 (7637), 359-364, 2017
Positive cross-regulatory loop ties GATA-3 to estrogen receptor α expression in breast cancer
J Eeckhoute, EK Keeton, M Lupien, SA Krum, JS Carroll, M Brown
Cancer research 67 (13), 6477-6483, 2007
Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer
SR Setlur, KD Mertz, Y Hoshida, F Demichelis, M Lupien, S Perner, ...
Journal of the National Cancer Institute 100 (11), 815-825, 2008
Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits
O Corradin, A Saiakhova, B Akhtar-Zaidi, L Myeroff, J Willis, ...
Genome research 24 (1), 1-13, 2014
Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy
X Lan, DJ Jörg, FMG Cavalli, LM Richards, LV Nguyen, RJ Vanner, ...
Nature 549 (7671), 227-232, 2017
Epigenomic enhancer profiling defines a signature of colon cancer
B Akhtar-Zaidi, R Cowper-Salˇ lari, O Corradin, A Saiakhova, CF Bartels, ...
Science 336 (6082), 736-739, 2012
Breast cancer risk–associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression
R Cowper-Salˇ lari, X Zhang, JB Wright, SD Bailey, MD Cole, J Eeckhoute, ...
Nature genetics 44 (11), 1191-1198, 2012
Epigenetic switch involved in activation of pioneer factor FOXA1-dependent enhancers
AA Sérandour, S Avner, F Percevault, F Demay, M Bizot, ...
Genome research 21 (4), 555-565, 2011
Intratumor DNA methylation heterogeneity reflects clonal evolution in aggressive prostate cancer
D Brocks, Y Assenov, S Minner, O Bogatyrova, R Simon, C Koop, ...
Cell reports 8 (3), 798-806, 2014
Risk SNP-mediated promoter-enhancer switching drives prostate cancer through lncRNA PCAT19
JT Hua, M Ahmed, H Guo, Y Zhang, S Chen, F Soares, J Lu, S Zhou, ...
Cell 174 (3), 564-575. e18, 2018
CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1
S Frietze, M Lupien, PA Silver, M Brown
Cancer research 68 (1), 301-306, 2008
A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies
C Bahr, L Von Paleske, VV Uslu, S Remeseiro, N Takayama, SW Ng, ...
Nature 553 (7689), 515-520, 2018
Overexpression of activated murine Notch1 and Notch3 in transgenic mice blocks mammary gland development and induces mammary tumors
C Hu, A Diévart, M Lupien, E Calvo, G Tremblay, P Jolicoeur
The American journal of pathology 168 (3), 973-990, 2006
PharmacoGx: an R package for analysis of large pharmacogenomic datasets
P Smirnov, Z Safikhani, N El-Hachem, D Wang, A She, C Olsen, ...
Bioinformatics 32 (8), 1244-1246, 2016
PBX1 genomic pioneer function drives ERα signaling underlying progression in breast cancer
L Magnani, EB Ballantyne, X Zhang, M Lupien
PLoS genetics 7 (11), e1002368, 2011
Growth factor stimulation induces a distinct ERα cistrome underlying breast cancer endocrine resistance
M Lupien, CA Meyer, ST Bailey, J Eeckhoute, J Cook, T Westerling, ...
Genes & development 24 (19), 2219-2227, 2010
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