Spencer Phillips Hey
Spencer Phillips Hey
Harvard Medical School
Verified email at hms.harvard.edu
Cited by
Cited by
Are outcome-adaptive allocation trials ethical?
SP Hey, J Kimmelman
Clinical Trials 12 (2), 102-106, 2015
The questionable use of unequal allocation in confirmatory trials
SP Hey, J Kimmelman
Neurology 82 (1), 77-79, 2014
Benefit, risk, and outcomes in drug development: a systematic review of sunitinib
B Carlisle, N Demko, G Freeman, A Hakala, N MacKinnon, T Ramsay, ...
JNCI: Journal of the National Cancer Institute 108 (1), 2016
A systematic review of trial-level meta-analyses measuring the strength of association between surrogate end-points and overall survival in oncology
A Haslam, SP Hey, J Gill, V Prasad
European Journal of Cancer 106, 196-211, 2019
Assessment of the clinical benefit of cancer drugs receiving accelerated approval
B Gyawali, SP Hey, AS Kesselheim
JAMA internal medicine 179 (7), 906-913, 2019
Countering imprecision in precision medicine
SP Hey, AS Kesselheim
Science 353 (6298), 448-449, 2016
The Risk-escalation Model: A Principled Design Strategy for Early-phase Trials
SP Hey, J Kimmelman
Kennedy Institute of Ethics Journal 24 (2), 121, 2014
Accumulating Evidence and Research Organization (AERO) model: a new tool for representing, analyzing, and planning a translational research program
SP Hey, CM Heilig, C Weijer
Trials 14 (1), 159, 2013
A comparison of response patterns for progression-free survival and overall survival following treatment for cancer with pd-1 inhibitors: a meta-analysis of correlation and …
B Gyawali, SP Hey, AS Kesselheim
JAMA network open 1 (2), e180416-e180416, 2018
Heuristics and Meta-heuristics in Scientific Judgement
SP Hey
The British Journal for the Philosophy of Science 67 (2), 471-495, 2014
The Question of Clinical Equipoise and Patients’ Best Interests
SP Hey, RD Truog
AMA Journal of Ethics 17 (12), 1108-1115, 2015
The FDA, Juno Therapeutics, and the ethical imperative of transparency
SP Hey, AS Kesselheim
Bmj 354, i4435, 2016
Assay sensitivity and the epistemic contexts of clinical trials
SP Hey, C Weijer
Perspectives in Biology and Medicine 56 (1), 1-17, 2013
Is the concept of clinical equipoise still relevant to research?
SP Hey, AJ London, C Weijer, A Rid, F Miller
Bmj 359, 2017
Robust and discordant evidence: Methodological lessons from clinical research
SP Hey
Philosophy of Science 82 (1), 55-75, 2015
Reprioritizing Research Activity for the Post‐Antibiotic Era: Ethical, Legal, and Social Considerations
SP Hey, AS Kesselheim
Hastings Center Report 47 (2), 16-20, 2017
Success, failure, and transparency in biomarker-based drug development: a case study of cholesteryl ester transfer protein inhibitors
SP Hey, JM Franklin, J Avorn, AS Kesselheim
Circulation: Cardiovascular Quality and Outcomes 10 (6), e003121, 2017
What Theories Are Tested in Clinical Trials?
SP Hey
Philosophy of Science 82 (5), 1318-1329, 2015
Cell and gene therapy trials: are we facing an ‘evidence crisis’?
M Abou-El-Enein, SP Hey
EClinicalMedicine 7, 13-14, 2019
The Challenges of Validating in Precision Medicine: The Case of Excision Repair Cross‐Complement Group 1 Diagnostic Testing
B Barsanti‐Innes, SP Hey, J Kimmelman
The oncologist 22 (1), 89, 2017
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