| Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1 EL Mills, DG Ryan, HA Prag, D Dikovskaya, D Menon, Z Zaslona, ... Nature 556 (7699), 113-117, 2018 | 1273 | 2018 |
| The production of reactive oxygen species by complex I J Hirst, MS King, KR Pryde Biochemical Society Transactions 36 (5), 976-980, 2008 | 385 | 2008 |
| The molecular mechanism of transport by the mitochondrial ADP/ATP carrier JJ Ruprecht, MS King, T Zögg, AA Aleksandrova, E Pardon, PG Crichton, ... Cell 176 (3), 435-447. e15, 2019 | 237 | 2019 |
| The transport mechanism of the mitochondrial ADP/ATP carrier ERS Kunji, A Aleksandrova, MS King, H Majd, VL Ashton, E Cerson, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1863 (10), 2379-2393, 2016 | 147 | 2016 |
| Direct assignment of EPR spectra to structurally defined iron-sulfur clusters in complex I by double electron–electron resonance MM Roessler, MS King, AJ Robinson, FA Armstrong, J Harmer, J Hirst Proceedings of the National Academy of Sciences 107 (5), 1930-1935, 2010 | 147 | 2010 |
| Production of reactive oxygen species by complex I (NADH: ubiquinone oxidoreductase) from Escherichia coli and comparison to the enzyme from mitochondria D Esterházy, MS King, G Yakovlev, J Hirst Biochemistry 47 (12), 3964-3971, 2008 | 147 | 2008 |
| Recurrent De Novo Dominant Mutations in SLC25A4 Cause Severe Early-Onset Mitochondrial Disease and Loss of Mitochondrial DNA Copy Number K Thompson, H Majd, C Dallabona, K Reinson, MS King, CL Alston, L He, ... The American Journal of Human Genetics 99 (4), 860-876, 2016 | 129 | 2016 |
| Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH: ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species MS King, MS Sharpley, J Hirst Biochemistry 48 (9), 2053-2062, 2009 | 115 | 2009 |
| The SLC25 carrier family: important transport proteins in mitochondrial physiology and pathology ERS Kunji, MS King, JJ Ruprecht, C Thangaratnarajah Physiology 35 (5), 302-327, 2020 | 95 | 2020 |
| Formation of a cytoplasmic salt bridge network in the matrix state is a fundamental step in the transport mechanism of the mitochondrial ADP/ATP carrier MS King, M Kerr, PG Crichton, R Springett, ERS Kunji Biochimica et Biophysica Acta (BBA)-Bioenergetics 1857 (1), 14-22, 2016 | 75 | 2016 |
| Trends in thermostability provide information on the nature of substrate, inhibitor, and lipid interactions with mitochondrial carriers PG Crichton, Y Lee, JJ Ruprecht, E Cerson, C Thangaratnarajah, MS King, ... Journal of Biological Chemistry 290 (13), 8206-8217, 2015 | 72 | 2015 |
| The mitochondrial dicarboxylate and 2‐oxoglutarate carriers do not transport glutathione LM Booty, MS King, C Thangaratnarajah, H Majd, AM James, ERS Kunji, ... FEBS letters 589 (5), 621-628, 2015 | 72 | 2015 |
| Structural insight into mitochondrial β-barrel outer membrane protein biogenesis KA Diederichs, X Ni, SE Rollauer, I Botos, X Tan, MS King, ERS Kunji, ... Nature communications 11 (1), 3290, 2020 | 57 | 2020 |
| Structure of subcomplex Iβ of mammalian respiratory complex I leads to new supernumerary subunit assignments J Zhu, MS King, M Yu, L Klipcan, AGW Leslie, J Hirst Proceedings of the National Academy of Sciences 112 (39), 12087-12092, 2015 | 57 | 2015 |
| Investigating the properties of Bacillus thuringiensis Cry proteins with novel loop replacements created using combinatorial molecular biology CR Pigott, MS King, DJ Ellar Applied and environmental microbiology 74 (11), 3497-3511, 2008 | 52 | 2008 |
| How detergent impacts membrane proteins: atomic-level views of mitochondrial carriers in dodecylphosphocholine V Kurauskas, A Hessel, P Ma, P Lunetti, K Weinhäupl, L Imbert, ... The journal of physical chemistry letters 9 (5), 933-938, 2018 | 51 | 2018 |
| Screening of candidate substrates and coupling ions of transporters by thermostability shift assays H Majd, MS King, SM Palmer, AC Smith, LDH Elbourne, IT Paulsen, ... eLife 7, e38821, 2018 | 50 | 2018 |
| Mitochondrial oxodicarboxylate carrier deficiency is associated with mitochondrial DNA depletion and spinal muscular atrophy–like disease V Boczonadi, MS King, AC Smith, M Olahova, B Bansagi, A Roos, ... Genetics in Medicine 20 (10), 1224-1235, 2018 | 40 | 2018 |
| Calcium regulation of the human mitochondrial ATP-Mg/Pi carrier SLC25A24 uses a locking pin mechanism SPD Harborne, MS King, PG Crichton, ERS Kunji Scientific Reports 7 (1), 45383, 2017 | 34 | 2017 |
| Pathogenic mutations of the human mitochondrial citrate carrier SLC25A1 lead to impaired citrate export required for lipid, dolichol, ubiquinone and sterol synthesis H Majd, MS King, AC Smith, ERS Kunji Biochimica et Biophysica Acta (BBA)-Bioenergetics 1859 (1), 1-7, 2018 | 33 | 2018 |
Edmund R.S. KunjiProfessor of Biophysics, University of CambridgeVerified email at mrc-mbu.cam.ac.uk
