| Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels WJ Hadden, JL Young, AW Holle, ML McFetridge, DY Kim, P Wijesinghe, ... Proceedings of the National Academy of Sciences 114 (22), 5647-5652, 2017 | 479 | 2017 |
| Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro JL Young, AJ Engler Biomaterials 32 (4), 1002-1009, 2011 | 407 | 2011 |
| In vitro cancer cell–ECM interactions inform in vivo cancer treatment AW Holle, JL Young, JP Spatz Advanced drug delivery reviews 97, 270-279, 2016 | 217 | 2016 |
| Cell–extracellular matrix mechanobiology: forceful tools and emerging needs for basic and translational research AW Holle, JL Young, KJ Van Vliet, RD Kamm, D Discher, P Janmey, ... Nano letters 18 (1), 1-8, 2018 | 120 | 2018 |
| Stem cell mechanosensation on gelatin methacryloyl (GelMA) stiffness gradient hydrogels C Kim, JL Young, AW Holle, K Jeong, LG Major, JH Jeong, ZM Aman, ... Annals of biomedical engineering 48, 893-902, 2020 | 94 | 2020 |
| Nanoscale and mechanical properties of the physiological cell–ECM microenvironment JL Young, AW Holle, JP Spatz Experimental cell research 343 (1), 3-6, 2016 | 94 | 2016 |
| Mechanosensitive kinases regulate stiffness-induced cardiomyocyte maturation JL Young, K Kretchmer, MG Ondeck, AC Zambon, AJ Engler Scientific reports 4, 6425, 2014 | 86 | 2014 |
| BMP‐2 Signaling and Mechanotransduction Synergize to Drive Osteogenic Differentiation via YAP/TAZ Q Wei, A Holle, J Li, F Posa, F Biagioni, O Croci, AS Benk, J Young, ... Advanced Science, 1902931, 2020 | 83 | 2020 |
| Volume adaptation controls stem cell mechanotransduction LG Major, AW Holle, JL Young, MS Hepburn, K Jeong, IL Chin, ... ACS applied materials & interfaces 11 (49), 45520-45530, 2019 | 67 | 2019 |
| Ligand Diffusion Enables Force‐Independent Cell Adhesion via Activating α5β1 Integrin and Initiating Rac and RhoA Signaling L Yu, Y Hou, W Xie, JLC Camacho, C Cheng, A Holle, J Young, ... Advanced Materials, 2002566, 2020 | 57 | 2020 |
| Soft Hydrogels for Balancing Cell Proliferation and Differentiation Q Wei, J Young, A Holle, J Li, K Bieback, G Inman, JP Spatz, ... ACS Biomaterials Science & Engineering 6 (8), 4687-4701, 2020 | 41 | 2020 |
| In vivo response to dynamic hyaluronic acid hydrogels JL Young, J Tuler, R Braden, P Schüp-Magoffin, J Schaefer, K Kretchmer, ... Acta biomaterialia 9 (7), 7151-7157, 2013 | 39 | 2013 |
| Biointerface design for vertical nanoprobes R Elnathan, MG Barbato, X Guo, A Mariano, Z Wang, F Santoro, P Shi, ... Nature Reviews Materials 7 (12), 953-973, 2022 | 36 | 2022 |
| Integrin subtypes and nanoscale ligand presentation influence drug sensitivity in cancer cells JL Young, X Hua, H Somsel, F Reichart, H Kessler, JP Spatz Nano Letters 20 (2), 1183-1191, 2020 | 32 | 2020 |
| High content image analysis of focal adhesion-dependent mechanosensitive stem cell differentiation AW Holle, AJ McIntyre, J Kehe, P Wijesekara, JL Young, LG Vincent, ... Integrative Biology 8 (10), 1049-1058, 2016 | 25 | 2016 |
| Optically transparent vertical silicon nanowire arrays for live-cell imaging R Elnathan, AW Holle, J Young, MA George, O Heifler, A Goychuk, E Frey, ... Journal of nanobiotechnology 19 (1), 1-6, 2021 | 19 | 2021 |
| Integrin α5β1 nano-presentation regulates collective keratinocyte migration independent of substrate rigidity J Di Russo, JL Young, JWR Wegner, T Steins, H Kessler, JP Spatz eLife, 2021 | 13 | 2021 |
| NTA-Co3+-His6 versus NTA-Ni2+-His6 mediated E-Cadherin surface immobilization enhances cellular traction J Di Russo, JL Young, A Balakrishnan, AS Benk, JP Spatz Biomaterials 192, 171-178, 2019 | 11 | 2019 |
| The cardiac nanoenvironment: form and function at the nanoscale JP Singh, JL Young Biophysical Reviews 13 (5), 625-636, 2021 | 9 | 2021 |
| Hybrid hydrogel-extracellular matrix scaffolds identify distinct ligand and mechanical signatures in cardiac aging AR Sun, MFH Ramli, X Shen, D Chen, RS Foo, J Zhu, M Ackers-Johnson, ... bioRxiv, 2023.10. 06.561048, 2023 | 1 | 2023 |
Andrew HolleNational University of Singapore, Mechanobiology InstituteVerified email at nus.edu.sg
