Navdeep Chandel
Navdeep Chandel
Professor of Medicine, Biochemistry and Molecular Genetics, Northwestern University
Verified email at - Homepage
Cited by
Cited by
ROS function in redox signaling and oxidative stress
M Schieber, NS Chandel
Current biology 24 (10), R453-R462, 2014
Mitochondrial reactive oxygen species trigger hypoxia-induced transcription
NS Chandel, E Maltepe, E Goldwasser, CE Mathieu, MC Simon, ...
Proceedings of the National Academy of Sciences 95 (20), 11715-11720, 1998
Physiological roles of mitochondrial reactive oxygen species
LA Sena, NS Chandel
Molecular cell 48 (2), 158-167, 2012
Reactive oxygen species generated at mitochondrial complex III stabilize hypoxia-inducible factor-1α during hypoxia: a mechanism of O2 sensing
NS Chandel, DS McClintock, CE Feliciano, TM Wood, JA Melendez, ...
Journal of Biological Chemistry 275 (33), 25130-25138, 2000
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ...
Cell Death & Differentiation 25 (3), 486-541, 2018
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
MG Vander Heiden, NS Chandel, EK Williamson, PT Schumacker, ...
Cell 91 (5), 627-637, 1997
Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity
F Weinberg, R Hamanaka, WW Wheaton, S Weinberg, J Joseph, M Lopez, ...
Proceedings of the National Academy of Sciences 107 (19), 8788-8793, 2010
Fundamentals of cancer metabolism
RJ DeBerardinis, NS Chandel
Science advances 2 (5), e1600200, 2016
Reductive carboxylation supports growth in tumour cells with defective mitochondria
AR Mullen, WW Wheaton, ES Jin, PH Chen, LB Sullivan, T Cheng, ...
Nature 481 (7381), 385-388, 2012
AMPK regulates NADPH homeostasis to promote tumour cell survival during energy stress
SM Jeon, NS Chandel, N Hay
Nature 485 (7400), 661-665, 2012
Mitochondrial reactive oxygen species regulate cellular signaling and dictate biological outcomes
RB Hamanaka, NS Chandel
Trends in biochemical sciences 35 (9), 505-513, 2010
Targeting mitochondria metabolism for cancer therapy
SE Weinberg, NS Chandel
Nature chemical biology 11 (1), 9, 2015
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
L Galluzzi, JM Bravo-San Pedro, I Vitale, SA Aaronson, JM Abrams, ...
Cell Death & Differentiation 22 (1), 58-73, 2015
Mitochondria are required for antigen-specific T cell activation through reactive oxygen species signaling
LA Sena, S Li, A Jairaman, M Prakriya, T Ezponda, DA Hildeman, ...
Immunity 38 (2), 225-236, 2013
Oxygen sensing requires mitochondrial ROS but not oxidative phosphorylation
JK Brunelle, EL Bell, NM Quesada, K Vercauteren, V Tiranti, M Zeviani, ...
Cell metabolism 1 (6), 409-414, 2005
Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes
J Duranteau, NS Chandel, A Kulisz, Z Shao, PT Schumacker
Journal of biological chemistry 273 (19), 11619-11624, 1998
Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis
WW Wheaton, SE Weinberg, RB Hamanaka, S Soberanes, LB Sullivan, ...
elife 3, e02242, 2014
Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak
N Majewski, V Nogueira, P Bhaskar, PE Coy, JE Skeen, K Gottlob, ...
Molecular cell 16 (5), 819-830, 2004
ROS-dependent signal transduction
CR Reczek, NS Chandel
Current opinion in cell biology 33, 8-13, 2015
Bcl-xL prevents cell death following growth factor withdrawal by facilitating mitochondrial ATP/ADP exchange
MG Vander Heiden, NS Chandel, PT Schumacker, CB Thompson
Molecular cell 3 (2), 159-167, 1999
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