| SIRT1 deacetylates and inhibits SREBP-1C activity in regulation of hepatic lipid metabolism B Ponugoti, DH Kim, Z Xiao, Z Smith, J Miao, M Zang, SY Wu, CM Chiang, ... Journal of Biological Chemistry 285 (44), 33959-33970, 2010 | 567 | 2010 |
| Elevated microRNA‐34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT SE Choi, T Fu, S Seok, DH Kim, E Yu, KW Lee, Y Kang, X Li, B Kemper, ... Aging cell 12 (6), 1062-1072, 2013 | 253 | 2013 |
| Aberrantly elevated microRNA-34a in obesity attenuates hepatic responses to FGF19 by targeting a membrane coreceptor β-Klotho T Fu, SE Choi, DH Kim, S Seok, KM Suino-Powell, HE Xu, JK Kemper Proceedings of the National Academy of Sciences 109 (40), 16137-16142, 2012 | 153 | 2012 |
| A dysregulated acetyl/SUMO switch of FXR promotes hepatic inflammation in obesity DH Kim, Z Xiao, S Kwon, X Sun, D Ryerson, D Tkac, P Ma, SY Wu, ... The EMBO journal 34 (2), 184-199, 2015 | 126 | 2015 |
| The bacterial P450 BM3: a prototype for a biocatalyst with human P450 activities CH Yun, KH Kim, DH Kim, HC Jung, JG Pan Trends in biotechnology 25 (7), 289-298, 2007 | 123 | 2007 |
| Functional expression of human cytochrome P450 enzymes in Escherichia coli CH Yun, SK Yim, DH Kim, T Ahn Current drug metabolism 7 (4), 411-429, 2006 | 109 | 2006 |
| Generation of the human metabolite piceatannol from the anticancer-preventive agent resveratrol by bacterial cytochrome P450 BM3 DH Kim, T Ahn, HC Jung, JG Pan, CH Yun Drug metabolism and disposition 37 (5), 932-936, 2009 | 103 | 2009 |
| Hepatic Deletion of SIRT1 Decreases Hepatocyte Nuclear Factor 1α/Farnesoid X Receptor Signaling and Induces Formation of Cholesterol Gallstones in Mice A Purushotham, Q Xu, J Lu, JF Foley, X Yan, DH Kim, JK Kemper, X Li Molecular and cellular biology 32 (7), 1226-1236, 2012 | 90 | 2012 |
| Postprandial FGF19-induced phosphorylation by Src is critical for FXR function in bile acid homeostasis S Byun, DH Kim, D Ryerson, YC Kim, H Sun, B Kong, P Yau, G Guo, ... Nature communications 9 (1), 2590, 2018 | 72 | 2018 |
| Engineering bacterial cytochrome P450 (P450) BM3 into a prototype with human P450 enzyme activity using indigo formation SH Park, DH Kim, D Kim, DH Kim, HC Jung, JG Pan, T Ahn, D Kim, ... Drug metabolism and disposition 38 (5), 732-739, 2010 | 71 | 2010 |
| Sirtuin 1 deacetylase: a key regulator of hepatic lipid metabolism JK Kemper, SE Choi, DH Kim Vitamins & hormones 91, 385-404, 2013 | 70 | 2013 |
| Generation of human metabolites of 7-ethoxycoumarin by bacterial cytochrome P450 BM3 DH Kim, KH Kim, DH Kim, KH Liu, HC Jung, JG Pan, CH Yun Drug metabolism and disposition 36 (11), 2166-2170, 2008 | 70 | 2008 |
| Surface display of heme-and diflavin-containing cytochrome P450 BM3 in Escherichia coli: A whole-cell biocatalyst for oxidation SK Yim, DH Kim, HC Jung, JG Pan, HS Kang, TH Ahn, CH Yun Journal of microbiology and biotechnology 20 (4), 712-717, 2010 | 65 | 2010 |
| Generation of human chiral metabolites of simvastatin and lovastatin by bacterial CYP102A1 mutants KH Kim, JY Kang, DH Kim, SH Park, SH Park, D Kim, KD Park, YJ Lee, ... Drug metabolism and disposition 39 (1), 140-150, 2011 | 58 | 2011 |
| Farnesoid X receptor protects against cisplatin-induced acute kidney injury by regulating the transcription of ferroptosis-related genes DH Kim, HI Choi, JS Park, CS Kim, EH Bae, SK Ma, SW Kim Redox biology 54, 102382, 2022 | 51 | 2022 |
| FXR primes the liver for intestinal FGF15 signaling by transient induction of β-Klotho T Fu, YC Kim, S Byun, DH Kim, S Seok, K Suino-Powell, HE Xu, B Kemper, ... Molecular Endocrinology 30 (1), 92-103, 2016 | 49 | 2016 |
| Src‐mediated crosstalk between FXR and YAP protects against renal fibrosis DH Kim, HI Choi, JS Park, CS Kim, EH Bae, SK Ma, SW Kim The FASEB Journal 33 (10), 11109-11122, 2019 | 48 | 2019 |
| Chimeric cytochromes P450 engineered by domain swapping and random mutagenesis for producing human metabolites of drugs JY Kang, SH Ryu, SH Park, GS Cha, DH Kim, KH Kim, AW Hong, T Ahn, ... Biotechnology and Bioengineering 111 (7), 1313-1322, 2014 | 47 | 2014 |
| Arginine methylation by PRMT5 at a naturally occurring mutation site is critical for liver metabolic regulation by small heterodimer partner D Kanamaluru, Z Xiao, S Fang, SE Choi, DH Kim, TD Veenstra, ... Molecular and Cellular Biology, 2011 | 45 | 2011 |
| Heterologous expression and characterization of wild-type human cytochrome P450 1A2 without conventional N-terminal modification in Escherichia coli DH Kim, KH Kim, EM Isin, FP Guengerich, HZ Chae, T Ahn, CH Yun Protein expression and purification 57 (2), 188-200, 2008 | 45 | 2008 |
