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Michael C Gregory
Michael C Gregory
Verified email at merck.com
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Cited by
Cited by
Year
Maturation and diversity of the VRC01-antibody lineage over 15 years of chronic HIV-1 infection
X Wu, Z Zhang, CA Schramm, MG Joyce, Y Do Kwon, T Zhou, Z Sheng, ...
Cell 161 (3), 470-485, 2015
2592015
Anti–transforming growth factor β receptor II antibody has therapeutic efficacy against primary tumor growth and metastasis through multieffects on cancer, stroma, and immune cells
Z Zhong, KD Carroll, D Policarpio, C Osborn, M Gregory, R Bassi, ...
Clinical Cancer Research 16 (4), 1191-1205, 2010
1332010
Unveiling the crucial intermediates in androgen production
PJ Mak, MC Gregory, IG Denisov, SG Sligar, JR Kincaid
Proceedings of the National Academy of Sciences 112 (52), 15856-15861, 2015
772015
Nanodiscs: a controlled bilayer surface for the study of membrane proteins
MA McLean, MC Gregory, SG Sligar
Annual review of biophysics 47, 107-124, 2018
762018
A neutralizing antibody recognizing primarily N-linked glycan targets the silent face of the HIV envelope
T Zhou, A Zheng, U Baxa, GY Chuang, IS Georgiev, R Kong, S O’Dell, ...
Immunity 48 (3), 500-513. e6, 2018
762018
Differential hydrogen bonding in human CYP17 dictates hydroxylation versus lyase chemistry
M Gregory, PJ Mak, SG Sligar, JR Kincaid
Angewandte Chemie (International ed. in English) 52 (20), 5342, 2013
752013
Kinetic solvent isotope effect in human P450 CYP17A1-mediated androgen formation: evidence for a reactive peroxoanion intermediate
MC Gregory, IG Denisov, YV Grinkova, Y Khatri, SG Sligar
Journal of the American Chemical Society 135 (44), 16245-16247, 2013
742013
Nanodiscs in the studies of membrane-bound cytochrome P450 enzymes
A Luthra, M Gregory, YV Grinkova, IG Denisov, SG Sligar
Cytochrome P450 Protocols, 115-127, 2013
662013
Active site proton delivery and the lyase activity of human CYP17A1
Y Khatri, MC Gregory, YV Grinkova, IG Denisov, SG Sligar
Biochemical and biophysical research communications 443 (1), 179-184, 2014
652014
Interaction of KRas4b with anionic membranes: A special role for PIP2
MC Gregory, MA McLean, SG Sligar
Biochemical and biophysical research communications 487 (2), 351-355, 2017
522017
Evidence that cytochrome b5 acts as a redox donor in CYP17A1 mediated androgen synthesis
R Duggal, Y Liu, MC Gregory, IG Denisov, JR Kincaid, SG Sligar
Biochemical and biophysical research communications 477 (2), 202-208, 2016
422016
Human cytochrome CYP17A1: The structural basis for compromised lyase activity with 17-hydroxyprogesterone
PJ Mak, R Duggal, IG Denisov, MC Gregory, SG Sligar, JR Kincaid
Journal of the American Chemical Society 140 (23), 7324-7331, 2018
392018
Influence of transmembrane helix mutations on cytochrome P450-membrane interactions and function
G Mustafa, PP Nandekar, TJ Camp, NJ Bruce, MC Gregory, SG Sligar, ...
Biophysical journal 116 (3), 419-432, 2019
322019
Resonance Raman spectroscopy reveals that substrate structure selectively impacts the heme-bound diatomic ligands of CYP17
PJ Mak, MC Gregory, SG Sligar, JR Kincaid
Biochemistry 53 (1), 90-100, 2014
262014
Studies of : Gamma Rays, Lifetimes, and Mössbauer Effect
MC Gregory, BL Robinson, S Jha
Physical Review 180 (4), 1158, 1969
161969
Human P450 CYP17A1: control of substrate preference by asparagine 202
MC Gregory, PJ Mak, Y Khatri, JR Kincaid, SG Sligar
Biochemistry 57 (5), 764-771, 2018
92018
Importance of Asparagine 202 in manipulating active site structure and substrate preference for human CYP17A1
Y Liu, I Denisov, M Gregory, SG Sligar, JR Kincaid
Biochemistry 61 (7), 583-594, 2022
42022
Mechanism of the clinically relevant E305G mutation in human P450 CYP17A1
Y Liu, Y Grinkova, MC Gregory, IG Denisov, JR Kincaid, SG Sligar
Biochemistry 60 (43), 3262-3271, 2021
42021
The Mössbauer effect in 191Ir and 189Os
S Jha, WR Owens, MC Gregory, BL Robinson
Physics Letters B 25 (2), 115-117, 1967
41967
Understanding the mechanism of androgen biosynthesis
MC Gregory
University of Illinois at Urbana-Champaign, 2016
12016
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