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Nobuhiko Tokuriki
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Year
Protein dynamism and evolvability
N Tokuriki, DS Tawfik
Science 324 (5924), 203-207, 2009
8332009
Stability effects of mutations and protein evolvability
N Tokuriki, DS Tawfik
Current opinion in structural biology 19 (5), 596-604, 2009
7482009
How protein stability and new functions trade off
N Tokuriki, F Stricher, L Serrano, DS Tawfik
PLoS computational biology 4 (2), e1000002, 2008
4992008
Robustness–epistasis link shapes the fitness landscape of a randomly drifting protein
S Bershtein, M Segal, R Bekerman, N Tokuriki, DS Tawfik
Nature 444 (7121), 929-932, 2006
4242006
The stability effects of protein mutations appear to be universally distributed
N Tokuriki, F Stricher, J Schymkowitz, L Serrano, DS Tawfik
Journal of molecular biology 369 (5), 1318-1332, 2007
3772007
Chaperonin overexpression promotes genetic variation and enzyme evolution
N Tokuriki, DS Tawfik
Nature 459 (7247), 668-673, 2009
3512009
Protein folding by the effects of macromolecular crowding
N Tokuriki, M Kinjo, S Negi, M Hoshino, Y Goto, I Urabe, T Yomo
Protein Science 13 (1), 125-133, 2004
2312004
What makes an enzyme promiscuous?
A Babtie, N Tokuriki, F Hollfelder
Current opinion in chemical biology 14 (2), 200-207, 2010
2222010
Do viral proteins possess unique biophysical features?
N Tokuriki, CJ Oldfield, VN Uversky, IN Berezovsky, DS Tawfik
Trends in biochemical sciences 34 (2), 53-59, 2009
2202009
The role of protein dynamics in the evolution of new enzyme function
E Campbell, M Kaltenbach, GJ Correy, PD Carr, BT Porebski, ...
Nature chemical biology 12 (11), 944-950, 2016
1962016
Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme
N Tokuriki, CJ Jackson, L Afriat-Jurnou, KT Wyganowski, R Tang, ...
Nature Communications 3 (1), 1-10, 2012
1932012
Noise–mean relationship in mutated promoters
G Hornung, R Bar-Ziv, D Rosin, N Tokuriki, DS Tawfik, M Oren, N Barkai
Genome research 22 (12), 2409-2417, 2012
1572012
How mutational epistasis impairs predictability in protein evolution and design
CM Miton, N Tokuriki
Protein Science 25 (7), 1260-1272, 2016
1312016
Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase
CJ Jackson, JL Foo, N Tokuriki, L Afriat, PD Carr, HK Kim, G Schenk, ...
Proceedings of the National Academy of Sciences 106 (51), 21631-21636, 2009
1192009
Connectivity between catalytic landscapes of the metallo-β-lactamase superfamily
F Baier, N Tokuriki
Journal of Molecular Biology 426 (13), 2442-2456, 2014
982014
Evolvability of random polypeptides through functional selection within a small library
A Yamauchi, T Nakashima, N Tokuriki, M Hosokawa, H Nogami, S Arioka, ...
Protein engineering 15 (7), 619-626, 2002
842002
Evolutionary and molecular foundations of multiple contemporary functions of the nitroreductase superfamily
E Akiva, JN Copp, N Tokuriki, PC Babbitt
Proceedings of the National Academy of Sciences 114 (45), E9549-E9558, 2017
822017
Modulating protein stability–directed evolution strategies for improved protein function
RD Socha, N Tokuriki
The FEBS journal 280 (22), 5582-5595, 2013
792013
Dynamics and constraints of enzyme evolution
M Kaltenbach, N Tokuriki
Journal of Experimental Zoology Part B: Molecular and Developmental …, 2014
752014
Reverse evolution leads to genotypic incompatibility despite functional and active site convergence
M Kaltenbach, CJ Jackson, EC Campbell, F Hollfelder, N Tokuriki
Elife 4, e06492, 2015
682015
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