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Crispin Hiley
Crispin Hiley
Senior Lecturer, University College London
Verified email at ucl.ac.uk
Title
Cited by
Cited by
Year
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
N McGranahan, AJS Furness, R Rosenthal, S Ramskov, R Lyngaa, ...
Science 351 (6280), 1463-1469, 2016
29802016
Tracking the evolution of non–small-cell lung cancer
M Jamal-Hanjani, GA Wilson, N McGranahan, NJ Birkbak, TBK Watkins, ...
New England Journal of Medicine 376 (22), 2109-2121, 2017
21802017
Phylogenetic ctDNA analysis depicts early-stage lung cancer evolution
C Abbosh, NJ Birkbak, GA Wilson, M Jamal-Hanjani, T Constantin, ...
Nature 545 (7655), 446-451, 2017
17022017
Allele-specific HLA loss and immune escape in lung cancer evolution
N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ...
Cell 171 (6), 1259-1271. e11, 2017
11622017
Neoantigen-directed immune escape in lung cancer evolution
R Rosenthal, EL Cadieux, R Salgado, MA Bakir, DA Moore, CT Hiley, ...
Nature 567 (7749), 479-485, 2019
7302019
Fc effector function contributes to the activity of human anti-CTLA-4 antibodies
FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ...
Cancer cell 33 (4), 649-663. e4, 2018
5402018
Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors
FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ...
Immunity 46 (4), 577-586, 2017
4132017
Deciphering intratumor heterogeneity and temporal acquisition of driver events to refine precision medicine
C Hiley, EC de Bruin, N McGranahan, C Swanton
Genome biology 15, 1-10, 2014
2282014
Geospatial immune variability illuminates differential evolution of lung adenocarcinoma
K AbdulJabbar, SEA Raza, R Rosenthal, M Jamal-Hanjani, S Veeriah, ...
Nature medicine 26 (7), 1054-1062, 2020
2272020
Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse
F Chemi, DG Rothwell, N McGranahan, S Gulati, C Abbosh, SP Pearce, ...
Nature medicine 25 (10), 1534-1539, 2019
1732019
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer
K Joshi, MR de Massy, M Ismail, JL Reading, I Uddin, A Woolston, ...
Nature medicine 25 (10), 1549-1559, 2019
1672019
Challenges in molecular testing in non-small-cell lung cancer patients with advanced disease
CT Hiley, J Le Quesne, G Santis, R Sharpe, DG de Castro, G Middleton, ...
The Lancet 388 (10048), 1002-1011, 2016
1632016
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma
L Au, E Hatipoglu, MR de Massy, K Litchfield, G Beattie, A Rowan, ...
Cancer cell 39 (11), 1497-1518. e11, 2021
1522021
Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer
Z Kos, E Roblin, RS Kim, S Michiels, BD Gallas, W Chen, KK van de Vijver, ...
NPJ breast cancer 6 (1), 17, 2020
1312020
Expression of vascular endothelial growth factor (VEGF) in locally invasive prostate cancer is prognostic for radiotherapy outcome
MML Green, CT Hiley, JH Shanks, IC Bottomley, CML West, RA Cowan, ...
International Journal of Radiation Oncology* Biology* Physics 67 (1), 84-90, 2007
1082007
A clonal expression biomarker associates with lung cancer mortality
D Biswas, NJ Birkbak, R Rosenthal, CT Hiley, EL Lim, K Papp, S Boeing, ...
Nature medicine 25 (10), 1540-1548, 2019
882019
PRSS3 promotes tumour growth and metastasis of human pancreatic cancer
G Jiang, F Cao, G Ren, D Gao, V Bhakta, Y Zhang, H Cao, Z Dong, ...
Gut 59 (11), 1535-1544, 2010
872010
The T cell differentiation landscape is shaped by tumour mutations in lung cancer
E Ghorani, JL Reading, JY Henry, MR Massy, R Rosenthal, V Turati, ...
Nature cancer 1 (5), 546-561, 2020
862020
Antibodies against endogenous retroviruses promote lung cancer immunotherapy
KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ...
Nature 616 (7957), 563-573, 2023
842023
Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA
C Abbosh, AM Frankell, T Harrison, J Kisistok, A Garnett, L Johnson, ...
Nature 616 (7957), 553-562, 2023
832023
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