Modelling of the blood–brain barrier in drug discovery and development R Cecchelli, V Berezowski, S Lundquist, M Culot, M Renftel, MP Dehouck, ... Nature reviews Drug discovery 6 (8), 650-661, 2007 | 794 | 2007 |
In vitro models of the blood–brain barrier: an overview of commonly used brain endothelial cell culture models and guidelines for their use HC Helms, NJ Abbott, M Burek, R Cecchelli, PO Couraud, MA Deli, ... Journal of Cerebral Blood Flow & Metabolism 36 (5), 862-890, 2016 | 745 | 2016 |
A new function for the LDL receptor: transcytosis of LDL across the blood–brain barrier B Dehouck, L Fenart, MP Dehouck, A Pierce, G Torpier, R Cecchelli The Journal of cell biology 138 (4), 877-889, 1997 | 676 | 1997 |
An easier, reproducible, and mass‐production method to study the blood–brain barrier in vitro MP Dehouck, S Méresse, P Delorme, JC Fruchart, R Cecchelli Journal of neurochemistry 54 (5), 1798-1801, 1990 | 674 | 1990 |
In vitro models for the blood–brain barrier P Garberg, M Ball, N Borg, R Cecchelli, L Fenart, RD Hurst, T Lindmark, ... Toxicology in vitro 19 (3), 299-334, 2005 | 493 | 2005 |
In vitro model for evaluating drug transport across the blood–brain barrier R Cecchelli, B Dehouck, L Descamps, L Fenart, V Buée-Scherrer, ... Advanced drug delivery reviews 36 (2-3), 165-178, 1999 | 439 | 1999 |
Receptor-mediated transcytosis of lactoferrin through the blood-brain barrier C Fillebeen, L Descamps, MP Dehouck, L Fenart, M Benaı̈ssa, G Spik, ... Journal of Biological Chemistry 274 (11), 7011-7017, 1999 | 419 | 1999 |
Drug transfer across the blood‐brain barrier: correlation between in vitro and in vivo models MP Dehouck, P Jolliet‐Riant, F Brée, JC Fruchart, R Cecchelli, ... Journal of neurochemistry 58 (5), 1790-1797, 1992 | 350 | 1992 |
Peroxisome proliferator-activated receptor-α activation as a mechanism of preventive neuroprotection induced by chronic fenofibrate treatment D Deplanque, P Gelé, O Pétrault, I Six, C Furman, M Bouly, S Nion, ... Journal of Neuroscience 23 (15), 6264-6271, 2003 | 319 | 2003 |
A stable and reproducible human blood-brain barrier model derived from hematopoietic stem cells R Cecchelli, S Aday, E Sevin, C Almeida, M Culot, L Dehouck, C Coisne, ... PloS one 9 (6), e99733, 2014 | 317 | 2014 |
Indirect evidence that drug brain targeting using polysorbate 80-coated polybutylcyanoacrylate nanoparticles is related to toxicity JC Olivier, L Fenart, R Chauvet, C Pariat, R Cecchelli, W Couet Pharmaceutical research 16, 1836-1842, 1999 | 294 | 1999 |
Differential roles for endothelial ICAM-1, ICAM-2, and VCAM-1 in shear-resistant T cell arrest, polarization, and directed crawling on blood–brain barrier endothelium O Steiner, C Coisne, R Cecchelli, R Boscacci, U Deutsch, B Engelhardt, ... The Journal of Immunology 185 (8), 4846-4855, 2010 | 277 | 2010 |
Upregulation of the low density lipoprotein receptor at the blood-brain barrier: intercommunications between brain capillary endothelial cells and astrocytes B Dehouck, MP Dehouck, JC Fruchart, R Cecchelli Review & Expositor 84 (1), 465-473, 1987 | 273 | 1987 |
High transcytosis of melanotransferrin (P97) across the blood–brain barrier M Demeule, J Poirier, J Jodoin, Y Bertrand, RR Desrosiers, C Dagenais, ... Journal of neurochemistry 83 (4), 924-933, 2002 | 270 | 2002 |
Evaluation of effect of charge and lipid coating on ability of 60-nm nanoparticles to cross an in vitro model of the blood-brain barrier L Fenart, A Casanova, B Dehouck, C Duhem, S Slupek, R Cecchelli, ... Journal of Pharmacology and Experimental Therapeutics 291 (3), 1017-1022, 1999 | 269 | 1999 |
Bovine brain endothelial cells express tight junctions and monoamine oxidase activity in long‐term culture S Méresse, MP Dehouck, P Delorme, M Bensaïd, JP Tauber, C Delbart, ... Journal of neurochemistry 53 (5), 1363-1371, 1989 | 261 | 1989 |
VEGF-induced BBB permeability is associated with an MMP-9 activity increase in cerebral ischemia: both effects decreased by Ang-1 S Valable, J Montaner, A Bellail, V Berezowski, J Brillault, R Cecchelli, ... Journal of Cerebral Blood Flow & Metabolism 25 (11), 1491-1504, 2005 | 255 | 2005 |
Ca2+ regulation of connexin 43 hemichannels in C6 glioma and glial cells E De Vuyst, N Wang, E Decrock, M De Bock, M Vinken, M Van Moorhem, ... Cell calcium 46 (3), 176-187, 2009 | 239 | 2009 |
Prediction of Drug Transport Through the Blood-Brain Barrier in Vivo: A Comparison Between Two in Vitro Cell Models S Lundquist, M Renftel, J Brillault, L Fenart, R Cecchelli, MP Dehouck Pharmaceutical research 19, 976-981, 2002 | 226 | 2002 |
Tissue-type plasminogen activator crosses the intact blood-brain barrier by low-density lipoprotein receptor–related protein-mediated transcytosis K Benchenane, V Berezowski, C Ali, M Fernández-Monreal, ... Circulation 111 (17), 2241-2249, 2005 | 225 | 2005 |