| Design, Synthesis, and in Vitro Biological Evaluation of 1H-1,2,3-Triazole-4-carboxamide Derivatives as New Anti-influenza A Agents Targeting Virus Nucleoprotein H Cheng, J Wan, MI Lin, Y Liu, X Lu, J Liu, Y Xu, J Chen, Z Tu, ... Journal of medicinal chemistry 55 (5), 2144-2153, 2012 | 173 | 2012 |
| Rationally designed BCL6 inhibitors target activated B cell diffuse large B cell lymphoma MG Cardenas, W Yu, W Beguelin, MR Teater, H Geng, RL Goldstein, ... The Journal of clinical investigation 126 (9), 3351-3362, 2016 | 152 | 2016 |
| Design, synthesis and discovery of 5-hydroxyaurone derivatives as growth inhibitors against HUVEC and some cancer cell lines H Cheng, L Zhang, Y Liu, S Chen, H Cheng, X Lu, Z Zheng, GC Zhou European journal of medicinal chemistry 45 (12), 5950-5957, 2010 | 91 | 2010 |
| Synthesis, discovery and preliminary SAR study of benzofuran derivatives as angiogenesis inhibitors Y Chen, S Chen, X Lu, H Cheng, Y Ou, H Cheng, GC Zhou Bioorganic & medicinal chemistry letters 19 (7), 1851-1854, 2009 | 58 | 2009 |
| New benzimidazole-2-urea derivates as tubulin inhibitors W Wang, D Kong, H Cheng, L Tan, Z Zhang, X Zhuang, H Long, Y Zhou, ... Bioorganic & Medicinal Chemistry Letters 24 (17), 4250-4253, 2014 | 52 | 2014 |
| Identification of thiourea-based inhibitors of the B-cell lymphoma 6 BTB domain via NMR-based fragment screening and computer-aided drug design H Cheng, BM Linhares, W Yu, MG Cardenas, Y Ai, W Jiang, A Winkler, ... Journal of medicinal chemistry 61 (17), 7573-7588, 2018 | 41 | 2018 |
| Interferon γ is a STAT1-dependent direct inducer of BCL6 expression in imatinib-treated chronic myeloid leukemia cells HS Madapura, N Nagy, D Ujvari, T Kallas, MCL Kröhnke, S Amu, ... Oncogene 36 (32), 4619-4628, 2017 | 37 | 2017 |
| N-(3-Ethynyl-2,4-difluorophenyl)sulfonamide Derivatives as Selective Raf Inhibitors Y Li, H Cheng, Z Zhang, X Zhuang, J Luo, H Long, Y Zhou, Y Xu, ... ACS Medicinal Chemistry Letters 6 (5), 543-547, 2015 | 36 | 2015 |
| Identification and optimization of new dual inhibitors of B-Raf and epidermal growth factor receptor kinases for overcoming resistance against vemurafenib H Cheng, Y Chang, L Zhang, J Luo, Z Tu, X Lu, Q Zhang, J Lu, X Ren, ... Journal of Medicinal Chemistry 57 (6), 2692-2703, 2014 | 35 | 2014 |
| 2, 4-Diarylamino-pyrimidines as kinase inhibitors co-targeting IGF1R and EGFRL858R/T790M S Chan, K Han, R Qu, L Tong, Y Li, Z Zhang, H Cheng, X Lu, A Patterson, ... Bioorganic & Medicinal Chemistry Letters 25 (19), 4277-4281, 2015 | 20 | 2015 |
| Discovery of isoxazolyl-based inhibitors of Plasmodium falciparum cGMP-dependent protein kinase SU Mahmood, H Cheng, SR Tummalapalli, R Chakrasali, ... RSC Medicinal Chemistry 11 (1), 98-101, 2020 | 11 | 2020 |
| Design and synthesis of N-(4-aminopyridin-2-yl) amides as B-RafV600E inhibitors X Li, J Shen, L Tan, Z Zhang, D Gao, J Luo, H Cheng, X Zhou, J Ma, ... Bioorganic & Medicinal Chemistry Letters 26 (12), 2760-2763, 2016 | 8 | 2016 |
| BCL6 BTB‐specific inhibition via FX1 treatment reduces Tfh cells and reverses lymphoid follicle hyperplasia in Indian rhesus macaque (Macaca mulatta) Y Cai, MA Watkins, F Xue, Y Ai, H Cheng, CC Midkiff, X Wang, X Alvarez, ... Journal of medical primatology 49 (1), 26-33, 2020 | 7 | 2020 |
| Discovery of BRAF/HDAC dual inhibitors suppressing proliferation of human colorectal cancer cells Y Li, Y Huang, H Cheng, F Xu, R Qi, B Dai, Y Yang, Z Tu, L Peng, Z Zhang Frontiers in Chemistry 10, 910353, 2022 | 6 | 2022 |
| Enhanced QM/MM sampling for free energy calculation of chemical reactions: A case study of double proton transfer L Xie, H Cheng, D Fang, ZN Chen, M Yang The Journal of Chemical Physics 150 (4), 2019 | 5 | 2019 |
| Evaluation of benzamide derivatives as new influenza A nucleoprotein inhibitors J Liao, H Cheng, J Wan, P Chen, Y Li, K Ding, MD Tortorella, Z Tu, ... Open Journal of Medicinal Chemistry 6 (03), 43, 2016 | 4 | 2016 |
| Determination of A Novel Selective B-RafV600E Inhibitor (LXK4) in Dog Plasma by HPLC–MS/MS and its Application in a Pharmacokinetic Study E Jiang, J Deng, J Guo, Y Li, L Tan, H Cheng, R Dai Chromatographia 80, 71-76, 2017 | 1 | 2017 |
| Screening and identification of 3‐aryl‐quinolin‐2‐one derivatives as antiviral agents against influenza A H Cheng, L Fu, X Yang, Y Yang, Z Zhang, Y Tao, J Wan, Z Tu, J Chen, ... Journal of Medical Virology 95 (1), e28327, 2023 | | 2023 |
| Targeting HIV/SIV infection of CD4+ T follicular helper (Tfh) Cells: BCL6 inhibition represses HIV infection CD4+ T cells and reduces germinal center hyperplasia in rhesus macaque Y Cai, M Abdel-Mohsen, M Watkins, F Xue, Y Ai, H Cheng, C Midkiff, ... | | 2019 |
| Development of BCL6 protein-protein interaction inhibitors using a fragment-based approach B Linhares, H Cheng, W Yu, M Cardenas, Y Ai, W Jiang, A Melnick, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018 | | 2018 |
