| Structure-function analysis of STING activation by c [G (2′, 5′) pA (3′, 5′) p] and targeting by antiviral DMXAA P Gao, M Ascano, T Zillinger, W Wang, P Dai, AA Serganov, BL Gaffney, ... Cell 154 (4), 748-762, 2013 | 552 | 2013 |
| Phylogeny of mRNA capping enzymes SP Wang, L Deng, CK Ho, S Shuman Proceedings of the National Academy of Sciences 94 (18), 9573-9578, 1997 | 205 | 1997 |
| Modified vaccinia virus Ankara triggers type I IFN production in murine conventional dendritic cells via a cGAS/STING-mediated cytosolic DNA-sensing pathway P Dai, W Wang, H Cao, F Avogadri, L Dai, I Drexler, JA Joyce, XD Li, ... PLoS pathogens 10 (4), e1003989, 2014 | 192 | 2014 |
| White paper on microbial anti-cancer therapy and prevention NS Forbes, RS Coffin, L Deng, L Evgin, S Fiering, M Giacalone, ... Journal for immunotherapy of cancer 6, 1-24, 2018 | 126 | 2018 |
| Intratumoral delivery of inactivated modified vaccinia virus Ankara (iMVA) induces systemic antitumor immunity via STING and Batf3-dependent dendritic cells P Dai, W Wang, N Yang, C Serna-Tamayo, JM Ricca, D Zamarin, ... Science immunology 2 (11), eaal1713, 2017 | 121 | 2017 |
| Thalidomide inhibits tumor necrosis factor-α production and antigen presentation by Langerhans cells L Deng, W Ding, RD Granstein Journal of investigative dermatology 121 (5), 1060-1065, 2003 | 99 | 2003 |
| Identification of novel antipoxviral agents: mitoxantrone inhibits vaccinia virus replication by blocking virion assembly L Deng, P Dai, A Ciro, DF Smee, H Djaballah, S Shuman Journal of virology 81 (24), 13392-13402, 2007 | 98 | 2007 |
| Binding-pocket and lid-region substitutions render human STING sensitive to the species-specific drug DMXAA P Gao, T Zillinger, W Wang, M Ascano, P Dai, G Hartmann, T Tuschl, ... Cell reports 8 (6), 1668-1676, 2014 | 97 | 2014 |
| Vaccinia NPH-I, a DExH-box ATPase, is the energy coupling factor for mRNA transcription termination L Deng, S Shuman Genes & development 12 (4), 538-546, 1998 | 94 | 1998 |
| Dermoscopic findings in cutaneous metastases KA Chernoff, AA Marghoob, ME Lacouture, L Deng, KJ Busam, ... JAMA dermatology 150 (4), 429-433, 2014 | 77 | 2014 |
| Dermoscopic and reflectance confocal microscope findings of trichoepithelioma M Ardigo, J Zieff, A Scope, M Gill, P Spencer, L Deng, AA Marghoob Dermatology 215 (4), 354-358, 2007 | 76 | 2007 |
| Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells L Deng, P Dai, W Ding, RD Granstein, S Shuman Journal of virology 80 (20), 9977-9987, 2006 | 74 | 2006 |
| The D1 and D12 subunits are both essential for the transcription termination factor activity of vaccinia virus capping enzyme Y Luo, X Mao, L Deng, P Cong, S Shuman Journal of virology 69 (6), 3852-3856, 1995 | 64 | 1995 |
| Myxoma virus induces type I interferon production in murine plasmacytoid dendritic cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-dependent pathway P Dai, H Cao, T Merghoub, F Avogadri, W Wang, T Parikh, CM Fang, ... Journal of virology 85 (20), 10814-10825, 2011 | 59 | 2011 |
| Vaccinia virus subverts a mitochondrial antiviral signaling protein-dependent innate immune response in keratinocytes through its double-stranded RNA binding protein, E3 L Deng, P Dai, T Parikh, H Cao, V Bhoj, Q Sun, Z Chen, T Merghoub, ... Journal of virology 82 (21), 10735-10746, 2008 | 59 | 2008 |
| Structure-function analysis of the triphosphatase component of vaccinia virus mRNA capping enzyme L Yu, A Martins, L Deng, S Shuman Journal of virology 71 (12), 9837-9843, 1997 | 55 | 1997 |
| Innate immune response of human plasmacytoid dendritic cells to poxvirus infection is subverted by vaccinia E3 via its Z-DNA/RNA binding domain H Cao, P Dai, W Wang, H Li, J Yuan, F Wang, CM Fang, PM Pitha, J Liu, ... PLoS One 7 (5), e36823, 2012 | 50 | 2012 |
| A role for the H4 subunit of vaccinia RNA polymerase in transcription initiation at a viral early promoter. L Deng, S Shuman Journal of Biological Chemistry 269 (19), 14323-14328, 1994 | 44 | 1994 |
| Factor-dependent release of nascent RNA by ternary complexes of vaccinia RNA polymerase L Deng, J Hagler, S Shuman Journal of Biological Chemistry 271 (32), 19556-19562, 1996 | 43 | 1996 |
| Altered cutaneous immune parameters in transgenic mice overexpressing viral IL-10 in the epidermis W Ding, S Beissert, L Deng, E Miranda, C Cassetty, K Seiffert, ... The Journal of clinical investigation 111 (12), 1923-1931, 2003 | 38 | 2003 |
Taha MerghoubAssociate Professor, MSKVerified email at mskcc.org
