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Frederic Couture
Frederic Couture
TransBIOTech
Verified email at usherbrooke.ca
Title
Cited by
Cited by
Year
Therapeutic uses of furin and its inhibitors: a patent review
F Couture, A Kwiatkowska, YL Dory, R Day
Expert opinion on therapeutic patents 25 (4), 379-396, 2015
862015
On the cutting edge of proprotein convertase pharmacology: from molecular concepts to clinical applications
F Couture, F D'Anjou, R Day
Walter de Gruyter 2 (5), 421-438, 2011
792011
Role of proprotein convertases in prostate cancer progression
F Couture, F D'Anjou, R Desjardins, F Boudreau, R Day
Neoplasia 14 (11), 1032-IN6, 2012
672012
The Multi-Leu peptide inhibitor discriminates between PACE4 and furin and exhibits antiproliferative effects on prostate cancer cells
C Levesque, M Fugère, A Kwiatkowska, F Couture, R Desjardins, ...
Journal of Medicinal Chemistry 55 (23), 10501-10511, 2012
572012
PACE4 undergoes an oncogenic alternative splicing switch in cancer
F Couture, R Sabbagh, A Kwiatkowska, R Desjardins, SP Guay, ...
Cancer Research 77 (24), 6863-6879, 2017
492017
Design, synthesis, and structure–activity relationship studies of a potent PACE4 inhibitor
A Kwiatkowska, F Couture, C Levesque, K Ly, R Desjardins, ...
Journal of medicinal chemistry 57 (1), 98-109, 2014
422014
PACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction increased apoptosis and impaired neovascularisation.
C Levesque, F Couture, A Kwiatkowska, R Desjardins, B Guérin, ...
Oncotarget, 2015
372015
Implications of proprotein convertases in ovarian cancer cell proliferation and tumor progression: insights for PACE4 as a therapeutic target
R Longuespée, F Couture, C Levesque, A Kwiatkowska, R Desjardins, ...
Translational Oncology 7 (3), 410-419, 2014
372014
Optimization of furin inhibitors to protect against the activation of influenza hemagglutinin H5 and Shiga toxin
H Gagnon, S Beauchemin, A Kwiatkowska, F Couture, F D’Anjou, ...
Journal of Medicinal Chemistry 57 (1), 29-41, 2014
362014
PACE4 is an important driver of ZR-75-1 estrogen receptor-positive breast cancer proliferation and tumor progression
F Panet, F Couture, A Kwiatkowska, R Desjardins, B Guérin, R Day
European journal of cell biology 96 (5), 469-475, 2017
242017
Gastrointestinal stability and cytotoxicity of bacteriocins from Gram-positive and Gram-negative bacteria: a comparative in vitro study
S Soltani, S Zirah, S Rebuffat, F Couture, Y Boutin, E Biron, M Subirade, ...
Frontiers in Microbiology 12, 780355, 2022
192022
V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss
AH Mohammad, S Assadian, F Couture, KJ Lefebvre, W El-Assaad, ...
Oncotarget 10 (48), 4923, 2019
192019
PACE4-based molecular targeting of prostate cancer using an engineered 64Cu-radiolabeled peptide inhibitor
F Couture, C Levesque, V Dumulon-Perreault, S Ait-Mohand, F D’Anjou, ...
Neoplasia 16 (8), 634-643, 2014
172014
A Naked Eye‐Invisible Ratiometric Fluorescent Microneedle Tattoo for Real‐Time Monitoring of Inflammatory Skin Conditions
S Babity, F Couture, EVR Campos, S Hedtrich, R Hagen, D Fehr, ...
Advanced Healthcare Materials 11 (6), 2102070, 2022
162022
Rational design of a fluorescent microneedle tattoo for minimally invasive monitoring of lymphatic function
S Babity, AK Polomska, F Couture, M Bonmarin, D Fehr, M Detmar, ...
Journal of controlled release 327, 350-359, 2020
162020
Novel Insights into Structure–Activity Relationships of N‐Terminally Modified PACE4 Inhibitors
A Kwiatkowska, F Couture, C Levesque, K Ly, S Beauchemin, ...
ChemMedChem 11 (3), 289-301, 2016
162016
In vitro investigation of gastrointestinal stability and toxicity of 3-hyrdoxypropionaldehyde (reuterin) produced by Lactobacillus reuteri
S Soltani, F Couture, Y Boutin, LB Said, S Cashman-Kadri, M Subirade, ...
Toxicology Reports 8, 740-746, 2021
152021
Knockdown strategies for the study of proprotein convertases and proliferation in prostate cancer cells
F D’Anjou, F Couture, R Desjardins, R Day
Therapeutic Applications of Ribozymes and Riboswitches: Methods and …, 2014
132014
Evaluation of PACE4 isoforms as biomarkers in thyroid cancer
L Fradet, R Temmar, F Couture, M Belzile, PH Fortier, R Day
Journal of Otolaryngology-Head & Neck Surgery 47 (1), 63, 2018
122018
Enhanced anti-tumor activity of the Multi-Leu peptide PACE4 inhibitor transformed into an albumin-bound tumor-targeting prodrug
A Kwiatkowska, F Couture, S Ait-Mohand, R Desjardins, YL Dory, ...
Scientific Reports 9 (1), 2118, 2019
102019
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